NL7503344A - Werkwijze voor het bereiden van nieuwe indeno- furanen en indenothiofenen; werkwijze ter be- reiding van farmaceutische preparaten alsmede de aldus verkregen voorwerpen. - Google Patents
Werkwijze voor het bereiden van nieuwe indeno- furanen en indenothiofenen; werkwijze ter be- reiding van farmaceutische preparaten alsmede de aldus verkregen voorwerpen.Info
- Publication number
- NL7503344A NL7503344A NL7503344A NL7503344A NL7503344A NL 7503344 A NL7503344 A NL 7503344A NL 7503344 A NL7503344 A NL 7503344A NL 7503344 A NL7503344 A NL 7503344A NL 7503344 A NL7503344 A NL 7503344A
- Authority
- NL
- Netherlands
- Prior art keywords
- indenothiophens
- furans
- objects
- preparation
- pharmaceutical preparations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/10—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring unsubstituted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C07C45/75—Reactions with formaldehyde
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
- C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/94—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/457,662 US3931239A (en) | 1974-04-03 | 1974-04-03 | 6-Oxo-7-substituted-6H-indeno-[5,4-b]furan(and thiophene)-carboxylic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
NL7503344A true NL7503344A (nl) | 1975-10-07 |
Family
ID=23817642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL7503344A NL7503344A (nl) | 1974-04-03 | 1975-03-20 | Werkwijze voor het bereiden van nieuwe indeno- furanen en indenothiofenen; werkwijze ter be- reiding van farmaceutische preparaten alsmede de aldus verkregen voorwerpen. |
Country Status (9)
Country | Link |
---|---|
US (1) | US3931239A (xx) |
JP (1) | JPS5946232B2 (xx) |
CH (1) | CH618166A5 (xx) |
DE (1) | DE2514389C2 (xx) |
DK (1) | DK114975A (xx) |
FR (1) | FR2274293A1 (xx) |
GB (1) | GB1479823A (xx) |
NL (1) | NL7503344A (xx) |
SE (1) | SE7503276L (xx) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3984552A (en) * | 1975-02-24 | 1976-10-05 | Merck & Co., Inc. | 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids |
US6858615B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
US20090253714A1 (en) * | 2003-08-20 | 2009-10-08 | Johnson Michael R | Methods of reducing risk of infection from pathogens |
US7517471B2 (en) * | 2004-04-26 | 2009-04-14 | Merck Patent Gmbh | As-indacen derivatives |
US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
EP3428153A1 (en) | 2012-12-17 | 2019-01-16 | Parion Sciences, Inc. | 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds |
WO2014099676A1 (en) | 2012-12-17 | 2014-06-26 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration |
US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3483226A (en) * | 1967-06-12 | 1969-12-09 | Searle & Co | 16-oxa and 17 - oxa - d - homoestra - 1,3,5(10)-trien-3-ols and d-nor-seco-diols corresponding,ethers and esters thereof |
-
1974
- 1974-04-03 US US05/457,662 patent/US3931239A/en not_active Expired - Lifetime
-
1975
- 1975-03-20 DK DK114975A patent/DK114975A/da unknown
- 1975-03-20 NL NL7503344A patent/NL7503344A/xx not_active Application Discontinuation
- 1975-03-21 CH CH367575A patent/CH618166A5/de not_active IP Right Cessation
- 1975-03-21 SE SE7503276A patent/SE7503276L/xx unknown
- 1975-03-26 GB GB12696/75A patent/GB1479823A/en not_active Expired
- 1975-03-27 FR FR7509647A patent/FR2274293A1/fr active Granted
- 1975-04-02 DE DE2514389A patent/DE2514389C2/de not_active Expired
- 1975-04-03 JP JP50039895A patent/JPS5946232B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2514389A1 (de) | 1975-10-09 |
CH618166A5 (xx) | 1980-07-15 |
DK114975A (xx) | 1975-10-04 |
FR2274293A1 (fr) | 1976-01-09 |
GB1479823A (en) | 1977-07-13 |
DE2514389C2 (de) | 1984-05-24 |
SE7503276L (sv) | 1975-10-06 |
JPS50135072A (xx) | 1975-10-25 |
JPS5946232B2 (ja) | 1984-11-10 |
FR2274293B1 (xx) | 1979-06-29 |
US3931239A (en) | 1976-01-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NL7414947A (nl) | Werkwijze voor het bereiden van farmaceutische smetische preparaten. | |
NL7503696A (nl) | Werkwijze ter vervaardiging van farmaceutische preparaten, alsmede de aldus gevormde voort- brengselen. | |
NL149210B (nl) | Werkwijze voor de bereiding van poederlakpreparaten. | |
NL7416609A (nl) | Werkwijze ter bereiding van farmaceutische pre- paraten alsmede aldus verkregen preparaten en een werkwijze voor het bereiden van cefalospo- rinederivaten. | |
NL7506675A (nl) | Werkwijze ter bereiding van alkanolaminederivaten, werkwijze ter vervaardiging van farmaceutische pre- paraten hiermede, alsmede de aldus vervaardigde voortbrengselen. | |
NL7500560A (nl) | Werkwijze voor de bereiding van candicidine be- vattende schuimpreparaten. | |
NL7510535A (nl) | Werkwijze ter bereiding van nieuwe arylpiperi- dinen, alsmede werkwijze ter bereiding van farmaceutische preparaten. | |
NL7506584A (nl) | Werkwijze ter bereiding van farmaceutische prepa- raten en werkwijze ter bereiding van nieuwe ergo- linederivaten. | |
NL7512848A (nl) | Werkwijze voor de bereiding van contraceptieve stoffen en preparaten. | |
NL7501542A (nl) | Werkwijze ter bereiding van nieuwe preparaten. | |
NL7415174A (nl) | Werkwijze ter bereiding van nieuwe verbindingen, werkwijze ter vervaardiging van farmaceutische preparaten hiermede, alsmede de aldus gevormde voortbrengselen. | |
NL7503344A (nl) | Werkwijze voor het bereiden van nieuwe indeno- furanen en indenothiofenen; werkwijze ter be- reiding van farmaceutische preparaten alsmede de aldus verkregen voorwerpen. | |
NL7510486A (nl) | Werkwijze ter bereiding van nieuwe n-acylamino- -(alpha)-arylacetamido cephalosporine, werkwijze ter bereiding van farmaceutische preparaten hier- mede, alsmede de aldus gevormde voortbrengselen. | |
NL7503885A (nl) | Werkwijze ter bereiding van farmaceutische preparaten en werkwijze ter bereiding van nieuwe cefalosporineverbindingen. | |
NL7509053A (nl) | Werkwijze ter bereiding van farmaceutische pre- paraten en werkwijze ter bereiding van nieuwe cefalosporineverbindingen. | |
NL7501914A (nl) | Werkwijze voor het bereiden van cefalosporinen, alsmede de toepassing daarvan als farmaceutische preparaten. | |
NL7500645A (nl) | Werkwijze voor het bereiden van nieuwe anti- biotica; werkwijze ter bereiding van farmaceu- tische preparaten en de door toepassing daarvan verkregen voorwerpen. | |
NL7508073A (nl) | Werkwijze voor het bereiden van fungicide preparaten alsmede aldus verkregen gevormde preparaten. | |
NL7500224A (nl) | Werkwijze voor het bereiden van prostaglandine- oga; werkwijze ter bereiding van farmaceu- e preparaten, alsmede de door toepassing an vervaardigde voorwerpen. | |
NL7504588A (nl) | Werkwijze voor het bereiden van 5-oxo-5h-diben- zo(a.d.)cycloheptenen. werkwijze ter bereiding van farmaceutische preparaten, alsmede de aldus vervaardigde voorwerpen. | |
NL7512847A (nl) | Werkwijze voor de bereiding van contraceptieve stoffen en preparaten. | |
NL7507460A (nl) | Nieuwe cefalosporinederivaten, werkwijze voor het bereiden van deze derivaten, alsmede preparaten, die deze derivaten bevatten. | |
NL7613398A (nl) | Werkwijze voor de bereiding van nieuwe genees- middelen en aldus verkregen geneesmiddelen. | |
NL7514113A (nl) | Werkwijze ter bereiding van farmaceutische prepa- raten, gevormde farmaceutische preparaten, alsme- de werkwijze ter bereiding van nieuwe cefemverbin- dingen. | |
NL7514429A (nl) | Werkwijze ter bereiding van farmaceutische pre- paraten en werkwijze ter bereiding van nieuwe cefemverbindingen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BV | The patent application has lapsed |