NL7103459A - - Google Patents

Info

Publication number
NL7103459A
NL7103459A NL7103459A NL7103459A NL7103459A NL 7103459 A NL7103459 A NL 7103459A NL 7103459 A NL7103459 A NL 7103459A NL 7103459 A NL7103459 A NL 7103459A NL 7103459 A NL7103459 A NL 7103459A
Authority
NL
Netherlands
Application number
NL7103459A
Other versions
NL180835C (nl
NL180835B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7103459A publication Critical patent/NL7103459A/xx
Publication of NL180835B publication Critical patent/NL180835B/nl
Application granted granted Critical
Publication of NL180835C publication Critical patent/NL180835C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NLAANVRAGE7103459,A 1970-03-14 1971-03-15 Werkwijze voor het bereiden van 5-aza-pyrimidine-nucleosiden. NL180835C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2012888A DE2012888C3 (de) 1970-03-14 1970-03-14 Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden

Publications (3)

Publication Number Publication Date
NL7103459A true NL7103459A (nl) 1971-09-16
NL180835B NL180835B (nl) 1986-12-01
NL180835C NL180835C (nl) 1987-05-04

Family

ID=5765475

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7103459,A NL180835C (nl) 1970-03-14 1971-03-15 Werkwijze voor het bereiden van 5-aza-pyrimidine-nucleosiden.

Country Status (19)

Country Link
US (1) US3817980A (nl)
JP (1) JPS5527077B1 (nl)
AT (1) AT313481B (nl)
BE (1) BE764179A (nl)
CA (1) CA946379A (nl)
CH (1) CH552606A (nl)
CS (1) CS162741B2 (nl)
DE (1) DE2012888C3 (nl)
DK (1) DK152134C (nl)
ES (1) ES388193A1 (nl)
FI (1) FI56018C (nl)
FR (1) FR2085707B1 (nl)
GB (1) GB1351003A (nl)
HU (1) HU164144B (nl)
IL (1) IL36363A (nl)
NL (1) NL180835C (nl)
PL (1) PL81543B1 (nl)
SE (1) SE405253B (nl)
ZA (1) ZA711084B (nl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1531469A (en) * 1975-12-18 1978-11-08 Farmaceutici Italia Daunosamine nucleosides
US4171431A (en) * 1976-08-19 1979-10-16 The Upjohn Company Nucleosides and process
DE2721466A1 (de) * 1977-05-12 1978-11-16 Robugen Gmbh Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden
DE2757365A1 (de) * 1977-12-20 1979-06-21 Schering Ag Neues verfahren zur herstellung von nucleosiden
GB1601020A (en) 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
US4423212A (en) * 1980-12-18 1983-12-27 The Upjohn Company Nucleosides and process
US5099010A (en) * 1983-01-17 1992-03-24 Research Corporation Intermediates in the preparation of 3'-amino-2',3'-dideoxycytidine and the pharmacologically acceptable salts thereof
JPS60193997A (ja) * 1984-03-14 1985-10-02 Sumitomo Chem Co Ltd 新規シアノイミダゾ−ルリボヌクレオシド誘導体およびその製造法
US4730512A (en) * 1984-10-23 1988-03-15 Toyota Jidosha Kabushiki Kaisha Engine crankshaft structure
CA1301166C (en) * 1987-07-21 1992-05-19 John Nicholas Freskos Process for preparing 2-deoxynucleosides
US6982253B2 (en) * 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
CA2499036A1 (en) * 2002-09-24 2004-04-08 Koronis Pharmaceuticals, Incorporated 1,3,5-triazines for treatment of viral diseases
AU2013200662B2 (en) * 2003-03-17 2015-04-02 Celgene International Sarl Methods for isolating crystalline Form I of 5-azacytidine
AU2012209018B2 (en) * 2003-03-17 2015-04-02 Celgene International Sarl Methods for isolating crystalline Form I of 5-azacytidine
US7038038B2 (en) 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US6943249B2 (en) * 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
US20060128654A1 (en) * 2004-12-10 2006-06-15 Chunlin Tang Pharmaceutical formulation of cytidine analogs and derivatives
US20060128653A1 (en) * 2004-12-10 2006-06-15 Chunlin Tang Pharmaceutical formulation of decitabine
RU2488591C2 (ru) * 2007-09-26 2013-07-27 Маунт Синай Скул Оф Медсин Аналоги азацитидина и их применение
EP2048151A1 (en) * 2007-10-10 2009-04-15 Cilag AG Method for producing nucleosides by direct glycosylation of the nucleoside base
EP2050757A1 (en) * 2007-10-10 2009-04-22 Cilag AG Method of producing 2' -deoxy-5-azacytidine (Decitabine)
WO2009139888A1 (en) 2008-05-15 2009-11-19 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
EP2321302B1 (en) * 2008-08-01 2014-10-29 Dr. Reddy's Laboratories Ltd. Azacitidine process and polymorphs
US20100035354A1 (en) * 2008-08-06 2010-02-11 Ettore Bigatti Process for preparing azacytidine intermediate
AR073003A1 (es) 2008-08-08 2010-10-06 Scinopharm Taiwan Ltd Proceso para preparar 5-azacitosina nucleosidos y sus derivados
EP2410987B1 (en) 2009-03-23 2018-05-16 Ambit Biosciences Corporation Methods of treatment using combination therapy
US20100249394A1 (en) * 2009-03-26 2010-09-30 Albemarle Corporation Processes for producing decitabine
IT1399195B1 (it) 2010-03-30 2013-04-11 Chemi Spa Processo per la sintesi di azacitidina e decitabina
MX2013010945A (es) 2011-03-31 2014-03-12 Celgene Internat Sarl Sintesis de 5 - azacitidina.
EP2833905B1 (en) 2012-04-04 2018-05-02 Halozyme, Inc. Combination therapy with hyaluronidase and a tumor-targeted taxane
CN103884809B (zh) * 2013-08-28 2016-01-27 鲁南制药集团股份有限公司 一种地西他滨中间体的分析检测方法
JP6162349B1 (ja) * 2016-04-21 2017-07-12 大原薬品工業株式会社 ５−アザシチジン類の糖部シリルエーテル誘導体
CN108226309B (zh) 2016-12-13 2020-06-16 江苏奥赛康药业有限公司 一种右丙亚胺的分析方法
CN108239128B (zh) * 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 β-核苷类化合物的制备方法
CN110128485B (zh) * 2018-02-09 2022-06-07 鲁南制药集团股份有限公司 一种阿扎胞苷的制备方法
US20190351031A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1244790B (de) * 1963-10-29 1967-07-20 Ceskoslovenska Akademie Ved Verfahren zur Herstellung des cancerostatisch wirksamen 5-Azacytidins
GB1050899A (nl) * 1963-12-22
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
US3346561A (en) * 1965-10-24 1967-10-10 Merck & Co Inc Pyrimidine 3-deoxynucleosides
US3531464A (en) * 1966-10-21 1970-09-29 Us Health Education & Welfare Alternative synthesis of 2'-deoxy-5-(trifluoromethyl)-uridine and the alphaanomer thereof
CH527207A (de) * 1968-05-08 1972-08-31 Ceskoslovenska Akademie Ved Verfahren zur Herstellung von 1-Glycosyl-5-azacytosinen
CH507969A (de) * 1968-11-12 1971-05-31 Ceskoslovenska Akademie Ved Verfahren zur Herstellung von 1-Glycosyl-5-azacytosinen
CH532062A (de) * 1968-11-13 1972-12-31 Ceskoslovenska Akademie Ved Verfahren zur Herstellung von 1-Glykosyl-5-azacytosinen

Also Published As

Publication number Publication date
DK152134B (da) 1988-02-01
FR2085707A1 (nl) 1971-12-31
AT313481B (de) 1974-02-25
FR2085707B1 (nl) 1975-04-18
PL81543B1 (nl) 1975-08-30
NL180835C (nl) 1987-05-04
SE405253B (sv) 1978-11-27
DE2012888C3 (de) 1981-04-02
FI56018C (fi) 1979-11-12
US3817980A (en) 1974-06-18
IL36363A0 (en) 1971-05-26
IL36363A (en) 1974-05-16
ZA711084B (en) 1971-10-27
DK152134C (da) 1988-08-01
CS162741B2 (nl) 1975-07-15
JPS5527077B1 (nl) 1980-07-17
GB1351003A (en) 1974-04-24
BE764179A (fr) 1971-09-13
CA946379A (en) 1974-04-30
DE2012888B2 (de) 1980-07-10
SU374828A3 (nl) 1973-03-20
NL180835B (nl) 1986-12-01
CH552606A (de) 1974-08-15
FI56018B (fi) 1979-07-31
DE2012888A1 (de) 1971-09-30
ES388193A1 (es) 1973-05-01
HU164144B (nl) 1973-12-28

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee