NL6807187A - - Google Patents

Info

Publication number
NL6807187A
NL6807187A NL6807187A NL6807187A NL6807187A NL 6807187 A NL6807187 A NL 6807187A NL 6807187 A NL6807187 A NL 6807187A NL 6807187 A NL6807187 A NL 6807187A NL 6807187 A NL6807187 A NL 6807187A
Authority
NL
Netherlands
Application number
NL6807187A
Other versions
NL161359C (nl
NL161359B (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL6807187A publication Critical patent/NL6807187A/xx
Publication of NL161359B publication Critical patent/NL161359B/xx
Application granted granted Critical
Publication of NL161359C publication Critical patent/NL161359C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
NL6807187.A 1963-10-17 1968-05-21 Werkwijze voor de bereiding van farmaceutische prepara- ten met een werking op het hart-vaatstelsel op basis van aminoalkylindoolderivaten, de door toepassing daarvan verkregen gevormde voortbrengselen en werkwijze ter bereiding van de actieve verbindingen. NL161359C (nl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US317072A US3238215A (en) 1963-10-17 1963-10-17 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
GB00096/68A GB1218570A (en) 1963-10-17 1967-05-24 Indoles
GB2425667 1967-05-24

Publications (3)

Publication Number Publication Date
NL6807187A true NL6807187A (de) 1968-11-25
NL161359B NL161359B (nl) 1979-09-17
NL161359C NL161359C (nl) 1980-02-15

Family

ID=27256462

Family Applications (1)

Application Number Title Priority Date Filing Date
NL6807187.A NL161359C (nl) 1963-10-17 1968-05-21 Werkwijze voor de bereiding van farmaceutische prepara- ten met een werking op het hart-vaatstelsel op basis van aminoalkylindoolderivaten, de door toepassing daarvan verkregen gevormde voortbrengselen en werkwijze ter bereiding van de actieve verbindingen.

Country Status (10)

Country Link
US (2) US3238215A (de)
BE (1) BE715545A (de)
CH (5) CH540916A (de)
DE (1) DE1770460C3 (de)
FR (2) FR7787M (de)
GB (1) GB1218570A (de)
IE (1) IE32083B1 (de)
IN (1) IN115974B (de)
MY (1) MY7100196A (de)
NL (1) NL161359C (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2085684A1 (de) * 1970-03-07 1971-12-31 Krakowskie Zaklady Pharma

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
BE665245A (de) * 1964-06-11
US3412097A (en) * 1964-09-07 1968-11-19 Koninklijke Pharma Fab Nv Indole derivatives
US3445472A (en) * 1965-12-03 1969-05-20 American Home Prod Mono- and di-aroyl pyridylethyl and piperidylethyl indoles
US3984437A (en) * 1969-09-03 1976-10-05 Mitsubishi Chemical Industries Ltd. Basic dyestuff
US4028365A (en) * 1970-09-03 1977-06-07 John Wyeth & Brother Limited Benz[g]indolyl compounds
US4160862A (en) * 1972-06-12 1979-07-10 Sterling Drug Inc. 1-Acyl-3-(amino-lower-alkyl)indoles
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
US4061758A (en) * 1972-06-30 1977-12-06 John Wyeth & Brother Limited Treating hypertension and central nervous system abnormalities
US4024147A (en) * 1972-06-30 1977-05-17 John Wyeth & Brother Limited Heterocyclic compounds
US3869463A (en) * 1973-01-17 1975-03-04 Wyeth John & Brother Ltd N-phenyl derivatives of alkanoylamido piperidines
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
GB1413708A (en) * 1973-06-19 1975-11-12 Wyeth John & Brother Ltd Indole derivative
US4061641A (en) * 1973-10-10 1977-12-06 John Wyeth & Brother Limited Ureidopiperidino-ketoalkyl indoles
US4177279A (en) * 1973-10-10 1979-12-04 John Wyeth & Brother Ltd. 1-[(3-Indolyl)-alkyl]-piperidyl ureas and hypotensive compositions
GB1459506A (en) * 1974-02-18 1976-12-22 Wyeth John & Brother Ltd Piperidine derivatives
US3936464A (en) * 1974-10-25 1976-02-03 American Cyanamid Company 1-Acyl-3-[2-(4-phenyl-1-piperidinyl)ethyl]indolines
US4026938A (en) * 1974-12-27 1977-05-31 Sterling Drug Inc. 1-Phenyl-3-azacarbocyclic-ureas
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines
GB1498884A (en) * 1975-04-15 1978-01-25 Wyeth John & Brother Ltd Aminoacetamide-pyridyl-tetrahydropyridyl and-piperidyl derivatives
US4147786A (en) * 1976-02-02 1979-04-03 Ciba-Geigy Corporation 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1542137A (en) * 1976-03-12 1979-03-14 Wyeth John & Brother Ltd Process for preparing 3(piperidinoalkyl)indoles
GB1581620A (en) * 1977-02-23 1980-12-17 Sekisui Chemical Co Ltd Gas combustion system
DE2961867D1 (en) * 1978-06-24 1982-03-04 Merck Patent Gmbh Indolylalkyl amines, pharmaceutical preparations containing them and process for their manufacture
US4242347A (en) * 1979-06-18 1980-12-30 Ciba-Geigy Corporation Hypotensive indolylalkylpiperidyl guanidines and isoureas
US4428954A (en) 1980-11-01 1984-01-31 John Wyeth And Brother Limited Method for treatment of cerebrovascular disorders
ZA822995B (en) * 1981-05-21 1983-12-28 Wyeth John & Brother Ltd Slow release pharmaceutical composition
FR2530632A1 (fr) * 1982-07-26 1984-01-27 Bouchara Emile Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
DE3301758A1 (de) * 1983-01-20 1984-07-26 Merck Patent Gmbh, 6100 Darmstadt Indolderivate
JPS6084281A (ja) * 1983-09-14 1985-05-13 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド類
JPS60123485A (ja) * 1983-12-08 1985-07-02 Yoshitomi Pharmaceut Ind Ltd インド−ル−３−カルボキサミド誘導体
JPS60142981A (ja) * 1983-12-28 1985-07-29 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド誘導体
GB8406089D0 (en) * 1984-03-08 1984-04-11 Wyeth John & Brother Ltd Treatment/prevention of atherosclerotic disorders &c
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof
GB8422924D0 (en) * 1984-09-11 1984-10-17 Wyeth John & Brother Ltd Prevention of hypertension
EP0187122A3 (de) * 1985-01-03 1987-12-16 Ciba-Geigy Ag 1,3,4-Trisubstituierte Azacycloalkane bzw. Azacycloalkene
EP0187619A3 (de) * 1985-01-03 1987-08-26 Ciba-Geigy Ag 1,3-disubstituierte Tetrahydropyridine
GB8531666D0 (en) * 1985-12-23 1986-02-05 Wyeth John & Brother Ltd Indole derivatives
GB8531665D0 (en) * 1985-12-23 1986-02-05 Wyeth John & Brother Ltd Indole derivatives
US4757079A (en) * 1986-06-24 1988-07-12 Dynamac Corporaton Anti-hypertensive piperidine compounds
US5004812A (en) * 1987-06-26 1991-04-02 E. I. Du Pont De Nemours And Company Direct positive dimethine cyanine dyes containing 1-aryl-2-heteroaryl indole nucleus
GB8903036D0 (en) * 1989-02-10 1989-03-30 Glaxo Group Ltd Chemical compounds
IL101243A (en) * 1991-03-20 1999-12-22 Merck & Co Inc Pharmaceutical preparations for the treatment of benign prostatic hyperplasia containing steroid history
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
AU3162695A (en) * 1994-08-03 1996-03-04 Asta Medica Aktiengesellschaft Indol, indazol, pyridopyrrol and pyridopyrazol derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effects
TR200003130T2 (tr) * 1998-04-28 2001-01-22 Arzneimittelwerk Dresden Gmbh Yeni hidroksiindoller, bunların fosfodiesteraz 4 inhibitörleri olarak kullanımları ve hazırlanmaları için işlemler
HUP0104493A3 (en) 1998-09-30 2002-12-28 Takeda Pharmaceutical Drugs for improving vesical excretory strength
US20020065286A1 (en) * 2000-08-21 2002-05-30 Davies Michael John Treatment of wounds
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
GB0130219D0 (en) * 2001-12-18 2002-02-06 Pfizer Ltd Compounds for the treatment of sexual dysfunction
US20030229001A1 (en) * 2002-01-31 2003-12-11 Pfizer Inc. Treatment of male sexual dysfunction
RS20050106A (en) 2002-08-19 2007-11-15 Pfizer Products Inc., Combination therapy for hyperproliferative diseases
GB0219961D0 (en) 2002-08-28 2002-10-02 Pfizer Ltd Oxytocin inhibitors
US7323462B2 (en) * 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
PA8597401A1 (es) * 2003-03-14 2005-05-24 Pfizer Derivados del acido 3-(1-[3-(1,3-benzotiazol-6-il) propilcarbamoil] cicloalquil) propanoico como inhibidores de nep
US20040220186A1 (en) * 2003-04-30 2004-11-04 Pfizer Inc. PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
SG141430A1 (en) 2003-05-30 2008-04-28 Ranbaxy Lab Ltd Substituted pyrrole derivatives and their use as hmg-co inhibitors
US20050065158A1 (en) * 2003-07-16 2005-03-24 Pfizer Inc. Treatment of sexual dysfunction
US7291640B2 (en) * 2003-09-22 2007-11-06 Pfizer Inc. Substituted triazole derivatives as oxytocin antagonists
US20050267096A1 (en) * 2004-05-26 2005-12-01 Pfizer Inc New indazole and indolone derivatives and their use pharmaceuticals
US20050288270A1 (en) * 2004-05-27 2005-12-29 Pfizer Inc New aminopyridine derivatives and their use as pharmaceuticals
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
JP2008533193A (ja) * 2005-03-21 2008-08-21 ファイザー・リミテッド オキシトシン拮抗薬としての置換トリアゾール誘導体
EP1863795B1 (de) * 2005-03-21 2008-10-29 Pfizer Limited Substituierte triazolderivate als oxytocinantagonisten
EP1917257A1 (de) * 2005-08-10 2008-05-07 Pfizer Limited Substituierte triazolderivate als oxytocin-antagonisten
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
BRPI0618379A2 (pt) 2005-11-08 2011-08-30 Ranbaxy Lab Ltd processo para preparação do hemi-sal de cálcio do ácido (3r,5r) -7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroxime tilfenilamino) carbonil]-pirrol-1-il] -3, 5-diidroxi heptanóico
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
US8809382B2 (en) 2009-05-04 2014-08-19 The Royal Institution For The Advancement Of Learning/Mcgill University 5-oxo-ETE receptor antagonist compounds
AU2014255381A1 (en) 2013-04-17 2015-10-08 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
SG11201908351TA (en) * 2017-03-10 2019-10-30 Edmond J Lavoie Indole derivatives as efflux pump inhibitors
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2701797A (en) * 1955-02-08 - indolylmethyl
US2708197A (en) * 1952-05-24 1955-05-10 Upjohn Co Preparation of (hydroxy-3-indole)-alkylamines
US3014043A (en) * 1957-02-08 1961-12-19 Merck & Co Inc Serotonin antagonists
US3075986A (en) * 1958-01-09 1963-01-29 Rhone Poulenc Sa (1-piperdidylalkyl) derivatives of 3-indole
US3155668A (en) * 1960-04-11 1964-11-03 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl)-lower-alkyl]-tertiary amines and intermediates therefor
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3198807A (en) * 1961-07-25 1965-08-03 Substitutes carboxamide indoles and indolines
US3238215A (en) * 1963-10-17 1966-03-01 Sterling Drug Inc 1-[(3-, 2-, and 1-indolyl)-lower-alkyl-, lower-alkenyl-, and lower-alkynyl]piperidines
US3445472A (en) * 1965-12-03 1969-05-20 American Home Prod Mono- and di-aroyl pyridylethyl and piperidylethyl indoles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2085684A1 (de) * 1970-03-07 1971-12-31 Krakowskie Zaklady Pharma

Also Published As

Publication number Publication date
GB1218570A (en) 1971-01-06
CH528525A (de) 1972-09-30
IE32083L (en) 1968-11-24
NL161359C (nl) 1980-02-15
CH540916A (de) 1973-10-15
NL161359B (nl) 1979-09-17
IN115974B (de) 1975-08-16
BE715545A (de) 1968-11-22
US3238215A (en) 1966-03-01
DE1770460A1 (de) 1972-05-10
CH553796A (de) 1974-09-13
DE1770460B2 (de) 1978-07-13
CH542221A (de) 1973-11-15
CH551428A (de) 1974-07-15
FR7787M (de) 1970-03-31
IE32083B1 (en) 1973-04-04
MY7100196A (en) 1971-12-31
US3527761A (en) 1970-09-08
DE1770460C3 (de) 1979-03-22
FR1582086A (de) 1969-09-26

Similar Documents

Publication Publication Date Title
FR1582086A (de)
AR142945A1 (de)
AT260747B (de)
BE627012A (de)
BE608372A (de)
BE582314A (de)
BE622160A (de)
BE643290A (de)
BE643168A (de)
BE621517A (de)
BE621232A (de)
BE620325A (de)
BE619061A (de)
BE616967A (de)
BE616830A (de)
BE616247A (de)
BE635179A (de)
BE626986A (de)
BE614220A (de)
BE612803A (de)
BE627151A (de)
BE632904A (de)
BE603935A (de)
BE643796A (de)
BE571209A (de)

Legal Events

Date Code Title Description
NL80 Information provided on patent owner name for an already discontinued patent

Owner name: WYETH