GB1003802A
(en)
*
|
1963-06-04 |
1965-09-08 |
Searle & Co |
Pyrimidinone derivatives
|
GB1062357A
(en)
*
|
1965-03-23 |
1967-03-22 |
Pfizer & Co C |
Quinazolone derivatives
|
DE2027645A1
(de)
*
|
1970-06-05 |
1971-12-09 |
Byk Gulden Lomberg Chemische Fa bnk GmbH, 7750 Konstanz |
Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
|
US3900476A
(en)
*
|
1973-05-17 |
1975-08-19 |
Upjohn Co |
2(2'-pyrimidylamino)quinazolines and their preparation
|
US3959279A
(en)
*
|
1974-01-28 |
1976-05-25 |
Sandoz, Inc. |
1-Substituted-2-imino-quinazolin-4(1H)ones
|
US3936453A
(en)
*
|
1974-01-28 |
1976-02-03 |
Sandoz, Inc. |
1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones
|
US4113637A
(en)
*
|
1974-09-10 |
1978-09-12 |
Institut Francais Du Petrole |
Alkyl-guanidino-heterocyclic compounds, their manufacture and use as additives for fuels and lubricants
|
GB8429739D0
(en)
*
|
1984-11-24 |
1985-01-03 |
Fbc Ltd |
Fungicides
|
US5756502A
(en)
*
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
AU4858596A
(en)
*
|
1995-09-15 |
1997-04-01 |
Torrey Pines Institute For Molecular Studies |
Synthesis of quinazolinone libraries
|
US6258819B1
(en)
*
|
1999-08-05 |
2001-07-10 |
Syntex (U.S.A.) Llc |
Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
|
US7671200B2
(en)
*
|
1999-10-27 |
2010-03-02 |
Cytokinetics, Inc. |
Quinazolinone KSP inhibitors
|
US7230000B1
(en)
*
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
SI2223922T1
(sl)
*
|
2000-04-25 |
2016-04-29 |
Icos Corporation |
Inhibitorji humane fosfatidil-inositol 3-kinazne delta izoforme
|
JPWO2002094790A1
(ja)
*
|
2001-05-23 |
2004-09-09 |
三菱ウェルファーマ株式会社 |
縮合ヘテロ環化合物およびその医薬用途
|
US6753428B2
(en)
*
|
2001-11-20 |
2004-06-22 |
Cytokinetics, Inc. |
Process for the racemization of chiral quinazolinones
|
AU2003213092A1
(en)
*
|
2002-02-15 |
2003-09-09 |
Smithkline Beecham Corporation |
Syntheses of quinazolinones
|
US7214800B2
(en)
|
2002-05-09 |
2007-05-08 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
KR20050036911A
(ko)
*
|
2002-05-09 |
2005-04-20 |
싸이토키네틱스, 인코포레이티드 |
화합물들, 방법 및 조성물
|
EP1513820A4
(en)
*
|
2002-05-23 |
2006-09-13 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
CA2489367A1
(en)
*
|
2002-06-14 |
2003-12-24 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
JP2006501201A
(ja)
*
|
2002-07-23 |
2006-01-12 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物および方法
|
US20040048853A1
(en)
*
|
2002-08-21 |
2004-03-11 |
Gustave Bergnes |
Compounds, compositions, and methods
|
EP1558083A4
(en)
*
|
2002-09-30 |
2008-04-16 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
MXPA06001601A
(es)
*
|
2003-08-13 |
2006-08-25 |
Takeda Pharmaceutical |
Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa.
|
WO2005016349A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
EP1699777B1
(en)
*
|
2003-09-08 |
2012-12-12 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
WO2005030751A2
(en)
*
|
2003-09-08 |
2005-04-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
WO2005041888A2
(en)
*
|
2003-11-03 |
2005-05-12 |
Cytokinetics, Inc. |
Pyrimidin-4-one compounds, compositions and methods
|
US20050148593A1
(en)
*
|
2003-11-07 |
2005-07-07 |
Gustave Bergnes |
Compounds, compositions, and methods
|
US7439254B2
(en)
*
|
2003-12-08 |
2008-10-21 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
EA013427B1
(ru)
|
2004-03-15 |
2010-04-30 |
Такеда Фармасьютикал Компани Лимитед |
Ингибиторы дипептидилпептидазы
|
CN102229609A
(zh)
|
2004-05-13 |
2011-11-02 |
艾科斯有限公司 |
作为人磷脂酰肌醇3-激酶δ抑制剂的喹唑啉酮
|
WO2005117889A1
(en)
*
|
2004-05-25 |
2005-12-15 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic
|
WO2006068978A2
(en)
|
2004-12-21 |
2006-06-29 |
Takeda Pharmaceutial Company Limited |
Dipeptidyl peptidase inhibitors
|
US20080287469A1
(en)
*
|
2005-02-17 |
2008-11-20 |
Diacovo Thomas G |
Phosphoinositide 3-Kinase Inhibitors for Inhibiting Leukocyte Accumulation
|
DE102005024017A1
(de)
*
|
2005-05-25 |
2006-11-30 |
Merck Patent Gmbh |
Chinazolinone
|
AU2006290205B2
(en)
|
2005-09-14 |
2012-12-13 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
PE20070622A1
(es)
*
|
2005-09-14 |
2007-08-22 |
Takeda Pharmaceutical |
Administracion de inhibidores de dipeptidil peptidasa
|
WO2007035629A2
(en)
*
|
2005-09-16 |
2007-03-29 |
Takeda Pharmaceutical Company Limited |
Process for the preparation of pyrimidinedione derivatives
|
US20100029941A1
(en)
*
|
2006-03-28 |
2010-02-04 |
Takeda Pharmaceutical Company Limited |
Preparation of (r)-3-aminopiperidine dihydrochloride
|
CA2914168C
(en)
*
|
2006-03-28 |
2018-05-08 |
Atir Holding S.A. |
Pyrido[1,2-a]pyrimidin-4-one derivatives and their use in the treatment of sexual disorders
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
ES2370873T3
(es)
*
|
2006-09-13 |
2011-12-23 |
Takeda Pharmaceutical Company Limited |
Utilización del 2-6-(3-amino-piperidin-1-il)-3-metil-2,4-dioxo-3,4-dihidro-2h-pirimidin-1-ilmetil-4-fluoro-benzonitrilo para el tratamiento de la diabetes, el cáncer, los trastornos autoinmunitarios y la infección por el vih.
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
CA3092449A1
(en)
|
2008-11-13 |
2010-05-20 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
PE20120602A1
(es)
|
2009-03-24 |
2012-05-21 |
Gilead Calistoga Llc |
ATROPISOMEROS DE 2-[(6-AMINO-9H-PURIN-9-IL)METIL]-5-METIL-3-o-TOLILQUINAZOLIN-4(3H)-ONA
|
AP2011005956A0
(en)
*
|
2009-04-20 |
2011-10-31 |
Gilead Calistoga Llc |
Methods of treatment for solid tumors.
|
CA2768843A1
(en)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Treatment of liver disorders with pi3k inhibitors
|
EP3581567A1
(en)
|
2011-04-10 |
2019-12-18 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
JP2015509537A
(ja)
|
2012-03-05 |
2015-03-30 |
ギリアード カリストガ エルエルシー |
(s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの多形性形態
|
PT3083630T
(pt)
|
2013-12-20 |
2019-11-15 |
Gilead Calistoga Llc |
Procedimentos para inibidores da fosfatidilinositol 3-quinase
|
JP2017500319A
(ja)
|
2013-12-20 |
2017-01-05 |
ギリアード カリストガ エルエルシー |
(s)−2−(1−(9h−プリン−6−イルアミノ)プロピル)−5−フルオロ−3−フェニルキナゾリン−4(3h)−オンの塩酸塩の多形形態
|
CN106459005A
(zh)
|
2014-06-13 |
2017-02-22 |
吉利德科学公司 |
磷脂酰肌醇3‑激酶抑制剂
|