NL190488C - Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. - Google Patents

Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Info

Publication number
NL190488C
NL190488C NLAANVRAGE7905635,A NL7905635A NL190488C NL 190488 C NL190488 C NL 190488C NL 7905635 A NL7905635 A NL 7905635A NL 190488 C NL190488 C NL 190488C
Authority
NL
Netherlands
Prior art keywords
preparation
methyloxiranyl
phosphonate
propanediol
hydroxymethyl
Prior art date
Application number
NLAANVRAGE7905635,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7905635A (nl
NL190488B (nl
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NL7905635A publication Critical patent/NL7905635A/nl
Publication of NL190488B publication Critical patent/NL190488B/xx
Application granted granted Critical
Publication of NL190488C publication Critical patent/NL190488C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NLAANVRAGE7905635,A 1978-07-19 1979-07-19 Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. NL190488C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2585378 1978-07-19
IT25853/78A IT1112282B (it) 1978-07-19 1978-07-19 Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato

Publications (3)

Publication Number Publication Date
NL7905635A NL7905635A (nl) 1980-01-22
NL190488B NL190488B (nl) 1993-10-18
NL190488C true NL190488C (nl) 1994-03-16

Family

ID=11217928

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7905635,A NL190488C (nl) 1978-07-19 1979-07-19 Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Country Status (21)

Country Link
US (1) US4727065A (it)
JP (1) JPS5517381A (it)
AT (1) AT371823B (it)
AU (1) AU526464B2 (it)
BE (1) BE877286A (it)
CA (1) CA1108631A (it)
CH (1) CH640823A5 (it)
DE (1) DE2926847A1 (it)
DK (1) DK148023C (it)
ES (1) ES482268A1 (it)
FR (1) FR2431506A1 (it)
GB (1) GB2025975B (it)
GR (1) GR75071B (it)
IE (1) IE48781B1 (it)
IL (1) IL57680A (it)
IT (1) IT1112282B (it)
LU (1) LU81500A1 (it)
NL (1) NL190488C (it)
SE (1) SE440360B (it)
YU (1) YU41411B (it)
ZA (1) ZA793354B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1124610B (it) * 1979-10-18 1986-05-07 Zambo Spa Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato
IT1136652B (it) * 1981-06-04 1986-09-03 Crinos Industria Farmaco Compesizione farmaceutica di fosfomicina in compresse da succhiare
DE3203937C2 (de) * 1982-02-05 1985-10-03 Luc Dr. 4150 Krefeld Barrut Verfahren und Vorrichtung zum maschinellen Sanieren oder Korrigieren mindestens eines Zahnes oder zum maschinellen Vorbereiten mindestens eines Zahnes für eine festsitzende prothetische Restaurierung und zum maschinellen Herstellen der festsitzenden prothetischen Restaurierung
CH660306A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
CH660305A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
IT1231013B (it) * 1989-07-27 1991-11-08 Zambon Spa Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'.
US5191094A (en) * 1989-07-27 1993-03-02 Zambon Group S.P.A. Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability and processing
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
EP1762573A1 (en) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. A process for the preparation of fosfomycin salts
ES2385158B1 (es) * 2010-12-24 2013-05-28 Arafarma Group, S.A. Composición farmacéutica de fosfomicina
CN102807586B (zh) 2012-08-31 2015-05-13 东北制药集团股份有限公司 磷霉素氨盐的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639590A (en) * 1967-07-25 1972-02-01 Merck & Co Inc Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
US3641063A (en) * 1968-01-22 1972-02-08 Merck & Co Inc Antibiotic purification process

Also Published As

Publication number Publication date
DE2926847C2 (it) 1988-11-10
BE877286A (fr) 1979-12-27
ZA793354B (en) 1980-07-30
ATA484079A (de) 1982-12-15
SE7906172L (it) 1980-01-20
JPS6248678B2 (it) 1987-10-15
NL7905635A (nl) 1980-01-22
DK302379A (da) 1980-01-20
IT1112282B (it) 1986-01-13
FR2431506B1 (it) 1984-11-23
US4727065A (en) 1988-02-23
DK148023C (da) 1985-07-08
GB2025975B (en) 1983-02-02
DK148023B (da) 1985-02-04
SE440360B (sv) 1985-07-29
JPS5517381A (en) 1980-02-06
ES482268A1 (es) 1980-04-16
IL57680A (en) 1986-01-31
YU163279A (en) 1983-02-28
CA1108631A (en) 1981-09-08
YU41411B (en) 1987-04-30
IE48781B1 (en) 1985-05-15
IT7825853A0 (it) 1978-07-19
CH640823A5 (it) 1984-01-31
DE2926847A1 (de) 1980-02-07
FR2431506A1 (fr) 1980-02-15
GR75071B (it) 1984-07-13
IE791366L (en) 1980-01-19
AT371823B (de) 1983-08-10
AU4855279A (en) 1980-01-24
GB2025975A (en) 1980-01-30
AU526464B2 (en) 1983-01-13
NL190488B (nl) 1993-10-18
IL57680A0 (en) 1979-10-31
LU81500A1 (fr) 1979-10-31

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
SNR Assignments of patents or rights arising from examined patent applications

Owner name: ZAMBON GROUP S.P.A.

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 19990719