NL190488B - Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. - Google Patents

Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Info

Publication number
NL190488B
NL190488B NLAANVRAGE7905635,A NL7905635A NL190488B NL 190488 B NL190488 B NL 190488B NL 7905635 A NL7905635 A NL 7905635A NL 190488 B NL190488 B NL 190488B
Authority
NL
Netherlands
Prior art keywords
preparation
methyloxiranyl
phosphonate
hydroxymethyl
cis
Prior art date
Application number
NLAANVRAGE7905635,A
Other languages
English (en)
Other versions
NL190488C (nl
NL7905635A (nl
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NL7905635A publication Critical patent/NL7905635A/nl
Publication of NL190488B publication Critical patent/NL190488B/nl
Application granted granted Critical
Publication of NL190488C publication Critical patent/NL190488C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62—Quaternary ammonium compounds
    • C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NLAANVRAGE7905635,A 1978-07-19 1979-07-19 Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat. NL190488C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT25853/78A IT1112282B (it) 1978-07-19 1978-07-19 Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT2585378 1978-07-19

Publications (3)

Publication Number Publication Date
NL7905635A NL7905635A (nl) 1980-01-22
NL190488B true NL190488B (nl) 1993-10-18
NL190488C NL190488C (nl) 1994-03-16

Family

ID=11217928

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7905635,A NL190488C (nl) 1978-07-19 1979-07-19 Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2R-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.

Country Status (21)

Country Link
US (1) US4727065A (nl)
JP (1) JPS5517381A (nl)
AT (1) AT371823B (nl)
AU (1) AU526464B2 (nl)
BE (1) BE877286A (nl)
CA (1) CA1108631A (nl)
CH (1) CH640823A5 (nl)
DE (1) DE2926847A1 (nl)
DK (1) DK148023C (nl)
ES (1) ES482268A1 (nl)
FR (1) FR2431506A1 (nl)
GB (1) GB2025975B (nl)
GR (1) GR75071B (nl)
IE (1) IE48781B1 (nl)
IL (1) IL57680A (nl)
IT (1) IT1112282B (nl)
LU (1) LU81500A1 (nl)
NL (1) NL190488C (nl)
SE (1) SE440360B (nl)
YU (1) YU41411B (nl)
ZA (1) ZA793354B (nl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1124610B (it) * 1979-10-18 1986-05-07 Zambo Spa Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato
IT1136652B (it) * 1981-06-04 1986-09-03 Crinos Industria Farmaco Compesizione farmaceutica di fosfomicina in compresse da succhiare
DE3203937C2 (de) * 1982-02-05 1985-10-03 Luc Dr. 4150 Krefeld Barrut Verfahren und Vorrichtung zum maschinellen Sanieren oder Korrigieren mindestens eines Zahnes oder zum maschinellen Vorbereiten mindestens eines Zahnes für eine festsitzende prothetische Restaurierung und zum maschinellen Herstellen der festsitzenden prothetischen Restaurierung
CH660305A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
CH660306A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
IT1231013B (it) * 1989-07-27 1991-11-08 Zambon Spa Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'.
US5191094A (en) * 1989-07-27 1993-03-02 Zambon Group S.P.A. Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability and processing
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
EP1762573A1 (en) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. A process for the preparation of fosfomycin salts
ES2385158B1 (es) * 2010-12-24 2013-05-28 Arafarma Group, S.A. Composición farmacéutica de fosfomicina
CN102807586B (zh) 2012-08-31 2015-05-13 东北制药集团股份有限公司 磷霉素氨盐的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639590A (en) * 1967-07-25 1972-02-01 Merck & Co Inc Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
US3641063A (en) * 1968-01-22 1972-02-08 Merck & Co Inc Antibiotic purification process

Also Published As

Publication number Publication date
IT1112282B (it) 1986-01-13
DK148023C (da) 1985-07-08
FR2431506A1 (fr) 1980-02-15
AU526464B2 (en) 1983-01-13
JPS5517381A (en) 1980-02-06
GR75071B (nl) 1984-07-13
ES482268A1 (es) 1980-04-16
NL190488C (nl) 1994-03-16
LU81500A1 (fr) 1979-10-31
FR2431506B1 (nl) 1984-11-23
GB2025975B (en) 1983-02-02
IE48781B1 (en) 1985-05-15
AT371823B (de) 1983-08-10
DK148023B (da) 1985-02-04
IE791366L (en) 1980-01-19
IT7825853A0 (it) 1978-07-19
DK302379A (da) 1980-01-20
BE877286A (fr) 1979-12-27
GB2025975A (en) 1980-01-30
AU4855279A (en) 1980-01-24
ATA484079A (de) 1982-12-15
SE7906172L (nl) 1980-01-20
NL7905635A (nl) 1980-01-22
DE2926847C2 (nl) 1988-11-10
CH640823A5 (it) 1984-01-31
IL57680A0 (en) 1979-10-31
US4727065A (en) 1988-02-23
YU41411B (en) 1987-04-30
CA1108631A (en) 1981-09-08
ZA793354B (en) 1980-07-30
JPS6248678B2 (nl) 1987-10-15
YU163279A (en) 1983-02-28
SE440360B (sv) 1985-07-29
DE2926847A1 (de) 1980-02-07
IL57680A (en) 1986-01-31

Similar Documents

Publication Publication Date Title
IT7923223A0 (it) Rotore per giroplano.
NL7713152A (nl) Zwavel- en fosforbevattende organosiliciumver- bindingen, werkwijze voor de bereiding daarvan en toepassing daarvan.
NL7614584A (nl) Werkwijze voor de bereiding van n-fosfonomethyl- glycine.
ES487293A0 (es) Procedimiento de fabricacion de capacitores de pelicula me- talizada.
NL7903450A (nl) Polymere samenstellingen voor membranen.
NL7900695A (nl) Fosfor.
NO793383L (no) Fordampningsapparat.
NL190488B (nl) Bis(2-ammonium-2-hydroxymethyl-1,3-propaandiol)(2r-cis)-(3-methyloxiranyl)fosfonaat; werkwijze voor de bereiding daarvan; farmaceutisch preparaat.
NL7903418A (nl) Synchroniseerinrichting voor versnellingsbak.
NL7900894A (nl) Adsorbens voor kunstmatige organen.
NL183357B (nl) (2.3-dihydro-2.2-dimethyl-benzofuran-7-yloxy-n-methylcarbamoyl)-(n'-alkylcarbamoyl)-sulfiden, werkwijze voor de bereiding daarvan, werkwijze voor de bereiding van een insecticide preparaat alsmede werkwijze voor de bestrijding van insecten.
DK157451C (da) Analogifremgangsmaade til fremstilling af 2,4-diamino-6-alkoxybenzyl-5-methylpyridooe2,3-daapyrimidiner eller farmaceutisk acceptable syreadditionssalte deraf
IT7926898A0 (it) Procedimento per preparare 1,2,3-tiadiazol-5-il-uree.
IT8023300A0 (it) Aciluree, mezzi insetticidi contenenti tali composti nonche'procedimento per la loro preparazione.
NL7901598A (nl) Machine voor de fabricage van pallets.
IT7926581A0 (it) (2r-cis)-(0-metilossiranil)fosfonatmono(2-ammonio-2-idrossimetil-1,3-p o. ropandiolo)
FI791424A (fi) Substituerade 8-hydroxi-1-fenyl-2,3,4,5-tetrahydro-1h-3-benzazepiner foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar
DK148281C (da) Analogifremgangsmaade til fremstilling af 8a-substituerede 8,8a-desoxy-8,8a-dihydrooleandomycin-forbindelser eller farmaceutiskacceptable syreadditionssalte deraf
NL7901215A (nl) Dieetisch voedingsmiddel, werkwijze voor de bereiding daarvan.
NL7902985A (nl) Werkwijze voor de bereiding van zouten van pyrodruiven- zuur.
NL7710750A (nl) Pyrazolopyrimidinyl(thiono)(thiol)-fosfor(fosfon)- zuuresters, werkwijzen ter bereiding ervan, als- mede de toepassing als insecticiden en acariciden.
NL190535C (nl) Preparaten, omvattende lactaatdehydrogenase alsmede werkwijze voor de bereiding daarvan.
NL7705444A (nl) Werkwijze voor de bereiding van perfluor-4-oxo- -2,5-dimethyl-2-fluorcarbonyl-1,3-dioxolan.
BE878034A (nl) Dieticum, werkwijze voor de bereiding daarvan, toepassing daarvan
NL183337C (nl) Werkwijze voor isotopenscheiding.

Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
SNR Assignments of patents or rights arising from examined patent applications

Owner name: ZAMBON GROUP S.P.A.

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 19990719