ATA484079A - Verfahren zur herstellung des neuen bis-(2ammonium-2-hydoxymethyl-1,3-propandiol) (2r-cis) -(3-mithyl-oxiranyl)-phosponats - Google Patents

Verfahren zur herstellung des neuen bis-(2ammonium-2-hydoxymethyl-1,3-propandiol) (2r-cis) -(3-mithyl-oxiranyl)-phosponats

Info

Publication number
ATA484079A
ATA484079A AT0484079A AT484079A ATA484079A AT A484079 A ATA484079 A AT A484079A AT 0484079 A AT0484079 A AT 0484079A AT 484079 A AT484079 A AT 484079A AT A484079 A ATA484079 A AT A484079A
Authority
AT
Austria
Prior art keywords
mithyl
propandiole
phosponate
hydoxymethyl
oxiranyl
Prior art date
Application number
AT0484079A
Other languages
English (en)
Other versions
AT371823B (de
Inventor
Dario Dr Chiarino
Bella Davide Della
Vittorio Ferrari
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of ATA484079A publication Critical patent/ATA484079A/de
Application granted granted Critical
Publication of AT371823B publication Critical patent/AT371823B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505Phosphonic acids containing oxirane groups; esters thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/62Quaternary ammonium compounds
    • C07C211/63Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0484079A 1978-07-19 1979-07-11 Verfahren zur herstellung des neuen bis-(2ammonium-2-hydroxymethyl-1,3-propandiol) (2r-cis) -(3-methyl-oxiranyl)-phosponats AT371823B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT25853/78A IT1112282B (it) 1978-07-19 1978-07-19 Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato

Publications (2)

Publication Number Publication Date
ATA484079A true ATA484079A (de) 1982-12-15
AT371823B AT371823B (de) 1983-08-10

Family

ID=11217928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0484079A AT371823B (de) 1978-07-19 1979-07-11 Verfahren zur herstellung des neuen bis-(2ammonium-2-hydroxymethyl-1,3-propandiol) (2r-cis) -(3-methyl-oxiranyl)-phosponats

Country Status (21)

Country Link
US (1) US4727065A (de)
JP (1) JPS5517381A (de)
AT (1) AT371823B (de)
AU (1) AU526464B2 (de)
BE (1) BE877286A (de)
CA (1) CA1108631A (de)
CH (1) CH640823A5 (de)
DE (1) DE2926847A1 (de)
DK (1) DK148023C (de)
ES (1) ES482268A1 (de)
FR (1) FR2431506A1 (de)
GB (1) GB2025975B (de)
GR (1) GR75071B (de)
IE (1) IE48781B1 (de)
IL (1) IL57680A (de)
IT (1) IT1112282B (de)
LU (1) LU81500A1 (de)
NL (1) NL190488C (de)
SE (1) SE440360B (de)
YU (1) YU41411B (de)
ZA (1) ZA793354B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1124610B (it) * 1979-10-18 1986-05-07 Zambo Spa Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato
IT1136652B (it) * 1981-06-04 1986-09-03 Crinos Industria Farmaco Compesizione farmaceutica di fosfomicina in compresse da succhiare
DE3203937C2 (de) * 1982-02-05 1985-10-03 Luc Dr. 4150 Krefeld Barrut Verfahren und Vorrichtung zum maschinellen Sanieren oder Korrigieren mindestens eines Zahnes oder zum maschinellen Vorbereiten mindestens eines Zahnes für eine festsitzende prothetische Restaurierung und zum maschinellen Herstellen der festsitzenden prothetischen Restaurierung
CH660306A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
CH660305A5 (de) * 1984-10-05 1987-04-15 Schering Spa Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
IT1231013B (it) * 1989-07-27 1991-11-08 Zambon Spa Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'.
US5191094A (en) * 1989-07-27 1993-03-02 Zambon Group S.P.A. Mono (2-ammonium-2-hydroxymethyl-1,3-propanediol) (2R,cis)-1,2-epoxypropyl-phosphonate with improved characteristics of stability and processing
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
EP1762573A1 (de) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. Verfahren zur Herstellung von Fosfomycin-Salzen
ES2385158B1 (es) * 2010-12-24 2013-05-28 Arafarma Group, S.A. Composición farmacéutica de fosfomicina
CN102807586B (zh) 2012-08-31 2015-05-13 东北制药集团股份有限公司 磷霉素氨盐的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639590A (en) * 1967-07-25 1972-02-01 Merck & Co Inc Antibacterial composition containing (-) (cis-1 2-epoxypropyl) phosphoric acid
US3641063A (en) * 1968-01-22 1972-02-08 Merck & Co Inc Antibiotic purification process

Also Published As

Publication number Publication date
NL190488C (nl) 1994-03-16
DE2926847C2 (de) 1988-11-10
BE877286A (fr) 1979-12-27
ZA793354B (en) 1980-07-30
SE7906172L (de) 1980-01-20
JPS6248678B2 (de) 1987-10-15
NL7905635A (nl) 1980-01-22
DK302379A (da) 1980-01-20
IT1112282B (it) 1986-01-13
FR2431506B1 (de) 1984-11-23
US4727065A (en) 1988-02-23
DK148023C (da) 1985-07-08
GB2025975B (en) 1983-02-02
DK148023B (da) 1985-02-04
SE440360B (sv) 1985-07-29
JPS5517381A (en) 1980-02-06
ES482268A1 (es) 1980-04-16
IL57680A (en) 1986-01-31
YU163279A (en) 1983-02-28
CA1108631A (en) 1981-09-08
YU41411B (en) 1987-04-30
IE48781B1 (en) 1985-05-15
IT7825853A0 (it) 1978-07-19
CH640823A5 (it) 1984-01-31
DE2926847A1 (de) 1980-02-07
FR2431506A1 (fr) 1980-02-15
GR75071B (de) 1984-07-13
IE791366L (en) 1980-01-19
AT371823B (de) 1983-08-10
AU4855279A (en) 1980-01-24
GB2025975A (en) 1980-01-30
AU526464B2 (en) 1983-01-13
NL190488B (nl) 1993-10-18
IL57680A0 (en) 1979-10-31
LU81500A1 (fr) 1979-10-31

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Legal Events

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EIH Change in the person of patent owner
EIH Change in the person of patent owner
ELA Expired due to lapse of time