NL189846B - PROCESS FOR PREPARING A 14-HYDROXYMORFINAND DERIVATIVE. - Google Patents

PROCESS FOR PREPARING A 14-HYDROXYMORFINAND DERIVATIVE.

Info

Publication number
NL189846B
NL189846B NLAANVRAGE7703000,A NL7703000A NL189846B NL 189846 B NL189846 B NL 189846B NL 7703000 A NL7703000 A NL 7703000A NL 189846 B NL189846 B NL 189846B
Authority
NL
Netherlands
Prior art keywords
hydroxymorfinand
derivative
preparing
hydroxymorfinand derivative
Prior art date
Application number
NLAANVRAGE7703000,A
Other languages
Dutch (nl)
Other versions
NL7703000A (en
NL189846C (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/669,795 external-priority patent/US4058531A/en
Priority claimed from US05/769,808 external-priority patent/US4139534A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NL7703000A publication Critical patent/NL7703000A/en
Publication of NL189846B publication Critical patent/NL189846B/en
Application granted granted Critical
Publication of NL189846C publication Critical patent/NL189846C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
NLAANVRAGE7703000,A 1976-03-23 1977-03-18 PROCESS FOR PREPARING A 14-HYDROXYMORFINAND DERIVATIVE. NL189846C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/669,795 US4058531A (en) 1976-03-23 1976-03-23 Process for the preparation of 14-hydroxymorphinan derivatives
US05/769,808 US4139534A (en) 1977-02-17 1977-02-17 Process for the preparation of 14-hydroxymorphinan derivatives

Publications (3)

Publication Number Publication Date
NL7703000A NL7703000A (en) 1977-09-27
NL189846B true NL189846B (en) 1993-03-16
NL189846C NL189846C (en) 1993-08-16

Family

ID=27100195

Family Applications (2)

Application Number Title Priority Date Filing Date
NLAANVRAGE7703000,A NL189846C (en) 1976-03-23 1977-03-18 PROCESS FOR PREPARING A 14-HYDROXYMORFINAND DERIVATIVE.
NL960022C NL960022I1 (en) 1976-03-23 1996-09-16 Process for preparing a 14-hydroxymorphinan derivative.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL960022C NL960022I1 (en) 1976-03-23 1996-09-16 Process for preparing a 14-hydroxymorphinan derivative.

Country Status (8)

Country Link
JP (1) JPS52136176A (en)
CA (1) CA1086723A (en)
CH (1) CH629783A5 (en)
DK (2) DK155322C (en)
FI (1) FI61486C (en)
LU (1) LU77000A1 (en)
NL (2) NL189846C (en)
SE (1) SE431749B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0373510U (en) * 1989-11-15 1991-07-24

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634429A (en) * 1969-09-30 1972-01-11 Hoffmann La Roche Morphinan derivatives and preparation thereof
CA919668A (en) * 1970-06-20 1973-01-23 Murakami Masuo Morphinan derivatives
BE788478A (en) * 1971-09-08 1973-03-06 Bristol Myers Co PROCESS FOR PREPARING ANALGESIC COMPOUNDS
US3775414A (en) * 1972-05-10 1973-11-27 Bristol Myers Co Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
CA1086723A (en) 1980-09-30
CH629783A5 (en) 1982-05-14
FI770865A (en) 1977-09-24
FI61486C (en) 1982-08-10
NL960022I1 (en) 1996-12-02
DK597188D0 (en) 1988-10-27
JPS6139938B2 (en) 1986-09-06
DK597188A (en) 1988-10-27
FI61486B (en) 1982-04-30
NL7703000A (en) 1977-09-27
DK155322B (en) 1989-03-28
LU77000A1 (en) 1977-10-03
DK155322C (en) 1989-09-11
SE7703236L (en) 1977-09-24
JPS52136176A (en) 1977-11-14
SE431749B (en) 1984-02-27
NL189846C (en) 1993-08-16
DK160987C (en) 1991-11-11
DK160987B (en) 1991-05-13
DK123877A (en) 1977-09-24

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Legal Events

Date Code Title Description
BC A request for examination has been filed
BX A request for additional search has been filed
BY An additional search report has been drawn up
A85 Still pending on 85-01-01
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

AC1 Application for a supplementary protection certificate

Free format text: 960022, 960916

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 970318

BC1 Further communications concerning applications for a supplementary protection certificate

Free format text: 960022