NL177913C - Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen. - Google Patents

Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen.

Info

Publication number
NL177913C
NL177913C NLAANVRAGE7510778,A NL7510778A NL177913C NL 177913 C NL177913 C NL 177913C NL 7510778 A NL7510778 A NL 7510778A NL 177913 C NL177913 C NL 177913C
Authority
NL
Netherlands
Prior art keywords
tetrene
nona
dimethyl
phenyl
compounds
Prior art date
Application number
NLAANVRAGE7510778,A
Other languages
English (en)
Dutch (nl)
Other versions
NL7510778A (nl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL7510778A publication Critical patent/NL7510778A/xx
Application granted granted Critical
Publication of NL177913C publication Critical patent/NL177913C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/23Preparation of halogenated hydrocarbons by dehalogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/20Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/21Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C205/22Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having one nitro groups bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/045Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/16Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/18Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
NLAANVRAGE7510778,A 1974-09-26 1975-09-12 Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen. NL177913C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1303274A CH605562A5 (de) 1974-09-26 1974-09-26

Publications (2)

Publication Number Publication Date
NL7510778A NL7510778A (nl) 1976-03-30
NL177913C true NL177913C (nl) 1985-12-16

Family

ID=4388688

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7510778,A NL177913C (nl) 1974-09-26 1975-09-12 Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen.

Country Status (22)

Country Link
JP (1) JPS5951531B2 (de)
AR (1) AR212858A1 (de)
AT (1) AT346311B (de)
BE (1) BE833784A (de)
BR (1) BR7506154A (de)
CA (1) CA1050042A (de)
CH (1) CH605562A5 (de)
CU (1) CU34345A (de)
DD (1) DD122072A5 (de)
DE (1) DE2542612A1 (de)
FR (1) FR2285864B1 (de)
GB (1) GB1514975A (de)
HU (1) HU172958B (de)
IE (1) IE41801B1 (de)
IL (1) IL47929A (de)
LU (1) LU73452A1 (de)
NL (1) NL177913C (de)
NZ (1) NZ178425A (de)
PH (1) PH12883A (de)
SU (1) SU623515A3 (de)
YU (1) YU40124B (de)
ZA (1) ZA755208B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395575A (en) 1975-11-14 1983-07-26 Hoffmann-La Roche, Inc. 5(Halophenyl)-2-fluoro-pentadienals
US4321209A (en) 1975-11-14 1982-03-23 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4335248A (en) 1975-11-14 1982-06-15 Hoffmann-La Roche Inc. Fluorinated polyenes
US4338253A (en) 1975-11-14 1982-07-06 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4266073A (en) * 1975-11-14 1981-05-05 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4375563A (en) 1975-11-14 1983-03-01 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4201727A (en) 1976-11-14 1980-05-06 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4299995A (en) 1979-05-10 1981-11-10 Hoffmann-La Roche Inc. Fluorinated polyenes
CA1111441A (en) 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
US4200647A (en) * 1977-12-21 1980-04-29 Hoffmann-La Roche Inc. Vitamin A compositions to treat rheumatic disease
US4642318A (en) * 1982-11-17 1987-02-10 Klaus Wolff Method for decreasing radiation load in PUVA therapy
ZA854828B (en) * 1984-07-27 1986-03-26 Hoffmann La Roche Phenyl nonatetraenoic acid derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1109671B (de) * 1958-10-17 1961-06-29 Basf Ag Verfahren zur Herstellung von ª‡,ª‰-ungesaettigten Carbonsaeureestern oder der freien Saeuren

Also Published As

Publication number Publication date
YU40124B (en) 1985-08-31
IE41801L (en) 1976-03-26
JPS5951531B2 (ja) 1984-12-14
AR212858A1 (es) 1978-10-31
AT346311B (de) 1978-11-10
LU73452A1 (de) 1977-05-16
JPS51125233A (en) 1976-11-01
BR7506154A (pt) 1976-08-03
IE41801B1 (en) 1980-03-26
YU228775A (en) 1983-01-21
DE2542612A1 (de) 1976-04-22
ATA734775A (de) 1978-03-15
SU623515A3 (ru) 1978-09-05
NZ178425A (en) 1978-03-06
IL47929A0 (en) 1975-11-25
FR2285864B1 (fr) 1980-03-28
HU172958B (hu) 1979-01-28
DD122072A5 (de) 1976-09-12
CA1050042A (en) 1979-03-06
BE833784A (fr) 1976-03-25
IL47929A (en) 1978-07-31
DE2542612C2 (de) 1987-09-10
FR2285864A1 (fr) 1976-04-23
NL7510778A (nl) 1976-03-30
AU8418775A (en) 1977-02-24
CU34345A (es) 1979-09-08
GB1514975A (en) 1978-06-21
PH12883A (en) 1979-09-28
ZA755208B (en) 1976-07-28
CH605562A5 (de) 1978-09-29

Similar Documents

Publication Publication Date Title
NL7502450A (nl) Werkwijze voor het bereiden van werkzame cyclo- hexanolderivaten en van preparaten, die deze bevatten.
NL171987C (nl) Werkwijze voor het bereiden van geneesmiddelen en preparaten met daarin s-adenosyl-methionine-sulfonzuurzouten, alsmede werkwijze voor het bereiden van deze sam-sulfonzuurzouten.
NL7415477A (nl) Werkwijze voor het bereiden van diergenees- kundige preparaten.
NL7506421A (nl) Werkwijze voor het bereiden van chromanderivaten en farmaceutische preparaten, bevattende zoda- nige verbindingen.
NL7506404A (nl) Werkwijze ter bereiding van een geneesmiddel, zo gevormd geneesmiddel en werkwijze voor het berei- den van daartoe geschikte geneeskrachtige verbin- dingen.
NL7511857A (nl) Werkwijze voor het bereiden van derivaten van ure- um of thioureum, werkwijze voor het bereiden van een geneesmiddel, die deze verbinding bevat en het volgens deze werkwijze verkregen geneesmiddel.
NL7710380A (nl) Werkwijze ter bereiding van een geneesmiddel, zo gevormd geneesmiddel en werkwijze voor het bereiden van daartoe geschikte actieve ver- bindingen.
NL7414946A (nl) Werkwijze voor het bereiden van farmaceutische preparaten.
NL177913C (nl) Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen.
NL7507611A (nl) Werkwijze voor het bereiden van tetrahalogeenxylyl- eendiacrylaten, tetrahalogeenxylylacrylaten, penta- halogeenbenzylacrylaten, alsmede gesubstitueerde acrylaten.
NL7512489A (nl) Werkwijze voor het bereiden van antitumorglyco- side-geneesmiddelen.
NL159381B (nl) Werkwijze voor de bereiding van tegen ontstekingen werkzame verbindingen en preparaten die ze bevatten, alsmede werkwijze ter bereiding van de werkzame verbindingen.
NL178564C (nl) Werkwijze voor het bereiden van farmaceutische preparaten op basis van 1-gesubstitueerde pyrazolon-5-derivaten.
NL7409810A (nl) Werkwijze voor het bereiden van chemothera- peutisch actieve tetrahydroacridonen.
NL177822C (nl) Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen, alsmede daarvoor geschikte, geneeskrachtige verbindingen.
NL7514970A (nl) Werkwijze voor het bereiden van een geneesmid- del, zo gevormd geneesmiddel en werkwijze voor het bereiden van daartoe geschikte actieve componenten.
NL181801C (nl) Werkwijze voor het bereiden van geneeskrachtige verbindingen op basis van 1,1-difenyletheenderivaten, en voor de bereiding van geneesmiddelen, die deze verbindingen bevatten.
NL7704542A (nl) Werkwijze voor het bereiden van isothiazolopyri- dinederivaten, alsmede farmaceutische preparaten die deze verbinding bevatten.
NL7700637A (nl) Werkwijze voor het bereiden van gestogeenesters, alsmede geneesmiddelen, die deze esters bevatten.
NL7704252A (nl) Werkwijze voor het bereiden van esters van fenylazijnzuurverbindingen en insecticide- preparaten, die deze verbindingen bevatten.
NL7509013A (nl) Werkwijze voor het bereiden van 2-thiol-4,5-di- fenyloxazool s-derivaten.
NL7509711A (nl) Werkwijze voor het bereiden van 1-gesubstitueer- de 2-methyltetrahydropyrimidinen.
NL7510912A (nl) Werkwijze voor het bereiden van polyhydroxyalkyl- -3,5-di-gesubstitueerde-2,4,6-trijoodcarbanilaten.
NL178318B (nl) Werkwijze voor het bereiden van anti-emetisch werkzame geneesmiddelen en daarvoor geschikte aktieve verbindingen.
NL149181B (nl) Werkwijze voor het bereiden van insekticide preparaten, die fosforoamidothioaatderivaten bevatten en werkwijze voor het bereiden van deze fosforoamidothioaatderivaten.

Legal Events

Date Code Title Description
BC A request for examination has been filed
A85 Still pending on 85-01-01
SNR Assignments of patents or rights arising from examined patent applications

Owner name: F. HOFFMANN-LA ROCHE AG

V1 Lapsed because of non-payment of the annual fee