CH605562A5 - - Google Patents

Info

Publication number
CH605562A5
CH605562A5 CH1303274A CH1303274A CH605562A5 CH 605562 A5 CH605562 A5 CH 605562A5 CH 1303274 A CH1303274 A CH 1303274A CH 1303274 A CH1303274 A CH 1303274A CH 605562 A5 CH605562 A5 CH 605562A5
Authority
CH
Switzerland
Application number
CH1303274A
Inventor
Werner Dr Bollag
Rudolf Dr Rueegg
Gottlieb Ryser
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1303274A priority Critical patent/CH605562A5/xx
Priority to ZA00755208A priority patent/ZA755208B/xx
Priority to IL47929A priority patent/IL47929A/xx
Priority to NZ178425A priority patent/NZ178425A/xx
Priority to AU84187/75A priority patent/AU493137B2/en
Priority to CA234,206A priority patent/CA1050042A/en
Priority to YU2287/75A priority patent/YU40124B/xx
Priority to NLAANVRAGE7510778,A priority patent/NL177913C/xx
Priority to AR260364A priority patent/AR212858A1/es
Priority to US05/613,676 priority patent/US4054589A/en
Priority to PH17579A priority patent/PH12883A/en
Priority to CU7534345A priority patent/CU34345A/es
Priority to JP50114373A priority patent/JPS5951531B2/ja
Priority to DE19752542612 priority patent/DE2542612A1/de
Priority to HU75HO00001839A priority patent/HU172958B/hu
Priority to FR7529226A priority patent/FR2285864B1/fr
Priority to LU73452A priority patent/LU73452A1/xx
Priority to BR7506154*A priority patent/BR7506154A/pt
Priority to SU752178997A priority patent/SU623515A3/ru
Priority to IE2098/75A priority patent/IE41801B1/en
Priority to AT734775A priority patent/AT346311B/de
Priority to DD188555A priority patent/DD122072A5/xx
Priority to BE160342A priority patent/BE833784A/xx
Priority to ES441267A priority patent/ES441267A1/es
Priority to GB39545/75A priority patent/GB1514975A/en
Priority to US05/816,409 priority patent/US4107190A/en
Priority to US05/903,639 priority patent/US4163103A/en
Publication of CH605562A5 publication Critical patent/CH605562A5/xx
Priority to US06/019,025 priority patent/US4187247A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/23—Preparation of halogenated hydrocarbons by dehalogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/20—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C205/22—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having one nitro groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/045—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
CH1303274A 1974-09-26 1974-09-26 CH605562A5 (de)

Priority Applications (28)

Application Number Priority Date Filing Date Title
CH1303274A CH605562A5 (de) 1974-09-26 1974-09-26
ZA00755208A ZA755208B (en) 1974-09-26 1975-08-13 Polyene compounds
IL47929A IL47929A (en) 1974-09-26 1975-08-15 Phenylnona-2,4,6,8-tetraenoic acid -8,6,4,2-derivatives,their manufacture and pharmaceutical compositions containing them
NZ178425A NZ178425A (en) 1974-09-26 1975-08-19 Certain polyenes (containing at least one halogen atom): tumour inhibiting pharmaceutical compositions
AU84187/75A AU493137B2 (en) 1974-09-26 1975-08-21 Polyene compounds
CA234,206A CA1050042A (en) 1974-09-26 1975-08-26 Polyene compounds
YU2287/75A YU40124B (en) 1974-09-26 1975-09-10 Process for obtaining polyene compounds
NLAANVRAGE7510778,A NL177913C (nl) 1974-09-26 1975-09-12 Werkwijze voor het bereiden van geneesmiddelen, die ongewenste celgroei remmen op basis van 9-fenyl-3,7-dimethyl-nona-tetraeenverbindingen, alsmede daarvoor geschikte geneeskrachtige verbindingen.
AR260364A AR212858A1 (es) 1974-09-26 1975-09-12 Procedimiento para la preparacion de derivados farmaceuticamente activos fenipolieno carboxilicos
US05/613,676 US4054589A (en) 1974-09-26 1975-09-15 Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene esters
PH17579A PH12883A (en) 1974-09-26 1975-09-16 Polyene compounds
CU7534345A CU34345A (es) 1974-09-26 1975-09-18 Compuestos polienicos
JP50114373A JPS5951531B2 (ja) 1974-09-26 1975-09-23 ポリエン化合物の製造方法
DE19752542612 DE2542612A1 (de) 1974-09-26 1975-09-24 Polyenverbindungen
HU75HO00001839A HU172958B (hu) 1974-09-26 1975-09-24 Sposob poluchenija polien-soedinenijj
FR7529226A FR2285864B1 (fr) 1974-09-26 1975-09-24 Nouveaux derives polyeniques, leur procede de preparation et leur application en tant que medicaments
LU73452A LU73452A1 (de) 1974-09-26 1975-09-24
BR7506154*A BR7506154A (pt) 1974-09-26 1975-09-24 Processo para obtencao de compostos de polieno,e produtos assim obtidos
AT734775A AT346311B (de) 1974-09-26 1975-09-25 Verfahren zur herstellung von neuen polyenverbindungen
IE2098/75A IE41801B1 (en) 1974-09-26 1975-09-25 Polyene compounds, their preparation and compositions containing them
SU752178997A SU623515A3 (ru) 1974-09-26 1975-09-25 Способ получени полиеновых соединений или их солей
DD188555A DD122072A5 (de) 1974-09-26 1975-09-25
BE160342A BE833784A (fr) 1974-09-26 1975-09-25 Derives polyeniques
ES441267A ES441267A1 (es) 1974-09-26 1975-09-25 Un procedimiento para la preparacion de compuestos polieni- cos.
GB39545/75A GB1514975A (en) 1974-09-26 1975-09-26 Polyene compounds their preparation and compositions containing them
US05/816,409 US4107190A (en) 1974-09-26 1977-07-18 Novel compounds of 9-phenyl-3,7-dimethyl-2,4,6,8-nonatetraenamide
US05/903,639 US4163103A (en) 1974-09-26 1978-05-08 Novel derivatives of 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraene
US06/019,025 US4187247A (en) 1974-09-26 1979-03-08 9-Substituted phenyl-3,7-dimethyl-nona 2,4,6,8-tetraene compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1303274A CH605562A5 (de) 1974-09-26 1974-09-26

Publications (1)

Publication Number Publication Date
CH605562A5 true CH605562A5 (de) 1978-09-29

Family

ID=4388688

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1303274A CH605562A5 (de) 1974-09-26 1974-09-26

Country Status (22)

Country Link
JP (1) JPS5951531B2 (de)
AR (1) AR212858A1 (de)
AT (1) AT346311B (de)
BE (1) BE833784A (de)
BR (1) BR7506154A (de)
CA (1) CA1050042A (de)
CH (1) CH605562A5 (de)
CU (1) CU34345A (de)
DD (1) DD122072A5 (de)
DE (1) DE2542612A1 (de)
FR (1) FR2285864B1 (de)
GB (1) GB1514975A (de)
HU (1) HU172958B (de)
IE (1) IE41801B1 (de)
IL (1) IL47929A (de)
LU (1) LU73452A1 (de)
NL (1) NL177913C (de)
NZ (1) NZ178425A (de)
PH (1) PH12883A (de)
SU (1) SU623515A3 (de)
YU (1) YU40124B (de)
ZA (1) ZA755208B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375563A (en) 1975-11-14 1983-03-01 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4335248A (en) 1975-11-14 1982-06-15 Hoffmann-La Roche Inc. Fluorinated polyenes
US4338253A (en) 1975-11-14 1982-07-06 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4395575A (en) 1975-11-14 1983-07-26 Hoffmann-La Roche, Inc. 5(Halophenyl)-2-fluoro-pentadienals
US4201727A (en) 1976-11-14 1980-05-06 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4321209A (en) 1975-11-14 1982-03-23 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4266073A (en) * 1975-11-14 1981-05-05 Hoffmann-La Roche Inc. Fluorinated aromatic polyenes
US4299995A (en) 1979-05-10 1981-11-10 Hoffmann-La Roche Inc. Fluorinated polyenes
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
US4200647A (en) * 1977-12-21 1980-04-29 Hoffmann-La Roche Inc. Vitamin A compositions to treat rheumatic disease
US4642318A (en) * 1982-11-17 1987-02-10 Klaus Wolff Method for decreasing radiation load in PUVA therapy
ZA854828B (en) * 1984-07-27 1986-03-26 Hoffmann La Roche Phenyl nonatetraenoic acid derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1109671B (de) * 1958-10-17 1961-06-29 Basf Ag Verfahren zur Herstellung von ª‡,ª‰-ungesaettigten Carbonsaeureestern oder der freien Saeuren

Also Published As

Publication number Publication date
AR212858A1 (es) 1978-10-31
LU73452A1 (de) 1977-05-16
DE2542612A1 (de) 1976-04-22
DD122072A5 (de) 1976-09-12
IE41801L (en) 1976-03-26
ZA755208B (en) 1976-07-28
IE41801B1 (en) 1980-03-26
FR2285864A1 (fr) 1976-04-23
NZ178425A (en) 1978-03-06
SU623515A3 (ru) 1978-09-05
CA1050042A (en) 1979-03-06
GB1514975A (en) 1978-06-21
YU228775A (en) 1983-01-21
HU172958B (hu) 1979-01-28
NL177913C (nl) 1985-12-16
NL7510778A (nl) 1976-03-30
DE2542612C2 (de) 1987-09-10
AT346311B (de) 1978-11-10
JPS51125233A (en) 1976-11-01
IL47929A (en) 1978-07-31
YU40124B (en) 1985-08-31
IL47929A0 (en) 1975-11-25
AU8418775A (en) 1977-02-24
FR2285864B1 (fr) 1980-03-28
PH12883A (en) 1979-09-28
CU34345A (es) 1979-09-08
JPS5951531B2 (ja) 1984-12-14
BE833784A (fr) 1976-03-25
BR7506154A (pt) 1976-08-03
ATA734775A (de) 1978-03-15

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Legal Events

Date Code Title Description
PUE Assignment

Owner name: F. HOFFMANN-LA ROCHE AG

PL Patent ceased