NL171053C - Werkwijze voor de bereiding van bloedsuikergehalte verlagende benzeensulfonylureums en van preparaten, die ze bevatten. - Google Patents

Werkwijze voor de bereiding van bloedsuikergehalte verlagende benzeensulfonylureums en van preparaten, die ze bevatten.

Info

Publication number
NL171053C
NL171053C NLAANVRAGE7405187,A NL7405187A NL171053C NL 171053 C NL171053 C NL 171053C NL 7405187 A NL7405187 A NL 7405187A NL 171053 C NL171053 C NL 171053C
Authority
NL
Netherlands
Prior art keywords
lowering
preparation
blood sugar
preparations containing
sulfonylureas
Prior art date
Application number
NLAANVRAGE7405187,A
Other languages
English (en)
Dutch (nl)
Other versions
NL171053B (nl
NL7405187A (da
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7405187A publication Critical patent/NL7405187A/xx
Publication of NL171053B publication Critical patent/NL171053B/xx
Application granted granted Critical
Publication of NL171053C publication Critical patent/NL171053C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
NLAANVRAGE7405187,A 1973-05-04 1974-04-17 Werkwijze voor de bereiding van bloedsuikergehalte verlagende benzeensulfonylureums en van preparaten, die ze bevatten. NL171053C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US357466A US3879403A (en) 1973-05-04 1973-05-04 Benzenesulfonylurea derivatives

Publications (3)

Publication Number Publication Date
NL7405187A NL7405187A (da) 1974-11-06
NL171053B NL171053B (nl) 1982-09-01
NL171053C true NL171053C (nl) 1983-02-01

Family

ID=23405725

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7405187,A NL171053C (nl) 1973-05-04 1974-04-17 Werkwijze voor de bereiding van bloedsuikergehalte verlagende benzeensulfonylureums en van preparaten, die ze bevatten.

Country Status (27)

Country Link
US (1) US3879403A (da)
JP (1) JPS5839829B2 (da)
AR (1) AR202815A1 (da)
AT (1) AT342615B (da)
AU (1) AU460423B2 (da)
BE (1) BE813807A (da)
BG (1) BG25080A3 (da)
CA (1) CA1010042A (da)
CH (1) CH582675A5 (da)
CS (1) CS191232B2 (da)
DD (1) DD111679A5 (da)
DE (1) DE2419198C3 (da)
DK (1) DK141749B (da)
ES (1) ES425343A1 (da)
FI (1) FI55498C (da)
FR (1) FR2227865B1 (da)
GB (1) GB1450801A (da)
HU (1) HU166760B (da)
IE (1) IE39116B1 (da)
IL (1) IL44570A (da)
LU (1) LU69889A1 (da)
NL (1) NL171053C (da)
PL (1) PL96708B1 (da)
RO (2) RO69254A (da)
SE (1) SE389866B (da)
SU (1) SU632300A3 (da)
YU (1) YU106174A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706977A1 (de) * 1977-02-18 1978-08-24 Hoechst Ag Benzoesaeuren und deren derivate sowie verfahren zu ihrer herstellung
DE2720926C2 (de) * 1977-05-10 1983-02-17 Hoechst Ag, 6000 Frankfurt Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung
DK455480A (da) * 1979-11-30 1981-05-31 Du Pont Fremgangsmaade til fremstilling af herbicide n- (substituerede heterocycliske aminocarbonyl)-aromatiske sulfonamider
US4716231A (en) * 1987-04-27 1987-12-29 Pfizer Inc. Chlorination of 2-methoxynicotinic acid
JPH042618U (da) * 1990-04-25 1992-01-10
JP5148836B2 (ja) * 2005-04-21 2013-02-20 石原産業株式会社 ニコチン酸誘導体又はその塩の製造方法
AU2006240772B2 (en) * 2005-04-21 2011-11-10 Ishihara Sangyo Kaisha, Ltd. Method for producing nicotinic acid derivative or salt thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1031088A (en) * 1964-04-16 1966-05-25 Hoechst Ag Benzenesulphonyl-ureas and process for their manufacture

Also Published As

Publication number Publication date
BE813807A (fr) 1974-10-17
AU460423B2 (en) 1975-04-07
SE389866B (sv) 1976-11-22
ES425343A1 (es) 1976-06-01
LU69889A1 (da) 1974-11-21
JPS5013379A (da) 1975-02-12
IL44570A0 (en) 1974-06-30
NL171053B (nl) 1982-09-01
FR2227865A1 (da) 1974-11-29
IE39116L (en) 1974-11-04
AU6759874A (en)
RO69254A (ro) 1982-09-09
CH582675A5 (da) 1976-12-15
IL44570A (en) 1977-01-31
NL7405187A (da) 1974-11-06
DE2419198B2 (de) 1980-04-10
AT342615B (de) 1978-04-10
AR202815A1 (es) 1975-07-24
SU632300A3 (ru) 1978-11-05
IE39116B1 (en) 1978-08-02
PL96708B1 (pl) 1978-01-31
HU166760B (da) 1975-05-28
GB1450801A (en) 1976-09-29
RO64480A (fr) 1979-05-15
CS191232B2 (en) 1979-06-29
CA1010042A (en) 1977-05-10
ATA316874A (de) 1977-08-15
FI55498B (fi) 1979-04-30
US3879403A (en) 1975-04-22
BG25080A3 (en) 1978-07-12
DD111679A5 (da) 1975-03-05
YU106174A (en) 1982-02-28
DK141749B (da) 1980-06-09
FR2227865B1 (da) 1977-08-19
DE2419198C3 (de) 1980-12-11
FI55498C (fi) 1979-08-10
JPS5839829B2 (ja) 1983-09-01
DK141749C (da) 1980-10-27
DE2419198A1 (de) 1974-11-14

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee