NL1031845A1 - Pyrimidinederivaten voor de behandeling van abnormale celgroei. - Google Patents
Pyrimidinederivaten voor de behandeling van abnormale celgroei.Info
- Publication number
- NL1031845A1 NL1031845A1 NL1031845A NL1031845A NL1031845A1 NL 1031845 A1 NL1031845 A1 NL 1031845A1 NL 1031845 A NL1031845 A NL 1031845A NL 1031845 A NL1031845 A NL 1031845A NL 1031845 A1 NL1031845 A1 NL 1031845A1
- Authority
- NL
- Netherlands
- Prior art keywords
- treatment
- cell growth
- abnormal cell
- pyrimidine derivatives
- pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57131204P | 2004-05-14 | 2004-05-14 | |
US57131204 | 2004-05-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL1031845A1 true NL1031845A1 (nl) | 2006-07-31 |
NL1031845C2 NL1031845C2 (nl) | 2006-11-23 |
Family
ID=34966230
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1029045A NL1029045C2 (nl) | 2004-05-14 | 2005-05-13 | Pyrimidinederivaten voor de behandeling van abnormale celgroei. |
NL1031845A NL1031845C2 (nl) | 2004-05-14 | 2006-05-19 | Pyrimidinederivaten voor de behandeling van abnormale celgroei. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1029045A NL1029045C2 (nl) | 2004-05-14 | 2005-05-13 | Pyrimidinederivaten voor de behandeling van abnormale celgroei. |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP1751143A1 (nl) |
JP (1) | JP4099212B2 (nl) |
KR (1) | KR100886990B1 (nl) |
CN (2) | CN102127058A (nl) |
AP (1) | AP2241A (nl) |
AR (1) | AR049097A1 (nl) |
AU (2) | AU2005243397A1 (nl) |
BR (1) | BRPI0511138A (nl) |
CA (1) | CA2566707A1 (nl) |
CR (1) | CR8749A (nl) |
EA (1) | EA200601796A1 (nl) |
EC (1) | ECSP066997A (nl) |
GE (1) | GEP20104875B (nl) |
GT (1) | GT200500113A (nl) |
IL (1) | IL178828A0 (nl) |
MA (1) | MA28583B1 (nl) |
MX (1) | MXPA06011890A (nl) |
NL (2) | NL1029045C2 (nl) |
NO (1) | NO20064576L (nl) |
NZ (1) | NZ550448A (nl) |
PA (1) | PA8632601A1 (nl) |
PE (1) | PE20060240A1 (nl) |
TN (1) | TNSN06370A1 (nl) |
TW (1) | TWI303635B (nl) |
UY (1) | UY28894A1 (nl) |
WO (1) | WO2005111023A1 (nl) |
ZA (1) | ZA200608394B (nl) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1763514A2 (en) * | 2004-05-18 | 2007-03-21 | Rigel Pharmaceuticals, Inc. | Cycloalkyl substituted pyrimidinediamine compounds and their uses |
US20070032514A1 (en) * | 2005-07-01 | 2007-02-08 | Zahn Stephan K | 2,4-diamino-pyrimidines as aurora inhibitors |
EP1966207A2 (en) * | 2005-12-21 | 2008-09-10 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
DK2146779T3 (en) * | 2007-04-18 | 2016-11-28 | Pfizer Prod Inc | Sulfonylamid derivatives to treat abnormal cell growth. |
EP2183225A1 (en) * | 2007-07-17 | 2010-05-12 | Rigel Pharmaceuticals, Inc. | Cyclic amine substituted pyrimidinediamines as pkc inhibitors |
US8461147B2 (en) * | 2007-12-03 | 2013-06-11 | Boehringer Ingelheim International Gmbh | Diaminopyridines for the treatment of diseases which are characterised by excessive or anomal cell proliferation |
KR101956261B1 (ko) * | 2008-05-21 | 2019-03-08 | 어리어드 파마슈티칼스, 인코포레이티드 | 키나아제 억제제로서 포스포러스 유도체 |
US8410126B2 (en) * | 2009-05-29 | 2013-04-02 | Boehringer Ingelheim International Gmbh | Pyrimidine inhibitors of PKTK2 |
WO2011018517A1 (en) | 2009-08-14 | 2011-02-17 | Boehringer Ingelheim International Gmbh | Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives |
US8933227B2 (en) | 2009-08-14 | 2015-01-13 | Boehringer Ingelheim International Gmbh | Selective synthesis of functionalized pyrimidines |
US20120244141A1 (en) | 2010-09-28 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors |
WO2014174745A1 (ja) * | 2013-04-26 | 2014-10-30 | 国立大学法人京都大学 | Eg5阻害剤 |
CN109608444B (zh) * | 2018-11-27 | 2022-02-11 | 中国药科大学 | 含异吲哚啉酮的erk抑制剂及其制备方法与用途 |
CN111732548B (zh) * | 2020-06-11 | 2022-06-17 | 浙江大学 | N2-氨甲酰芳环-2-氨基嘧啶类衍生物及其医药用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9721437D0 (en) * | 1997-10-10 | 1997-12-10 | Glaxo Group Ltd | Heteroaromatic compounds and their use in medicine |
AR042586A1 (es) | 2001-02-15 | 2005-06-29 | Sugen Inc | 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa |
WO2003030909A1 (en) * | 2001-09-25 | 2003-04-17 | Bayer Pharmaceuticals Corporation | 2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer |
DK1625121T3 (da) * | 2002-12-20 | 2010-05-10 | Pfizer Prod Inc | Pyrimidinderivater til behandling af abnorm cellevækst |
UA80767C2 (en) * | 2002-12-20 | 2007-10-25 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
-
2005
- 2005-05-02 EP EP05732043A patent/EP1751143A1/en not_active Withdrawn
- 2005-05-02 CN CN2011100212904A patent/CN102127058A/zh active Pending
- 2005-05-02 AP AP2006003790A patent/AP2241A/xx active
- 2005-05-02 NZ NZ550448A patent/NZ550448A/en unknown
- 2005-05-02 JP JP2007512557A patent/JP4099212B2/ja active Active
- 2005-05-02 MX MXPA06011890A patent/MXPA06011890A/es unknown
- 2005-05-02 WO PCT/IB2005/001201 patent/WO2005111023A1/en active Application Filing
- 2005-05-02 KR KR1020067023767A patent/KR100886990B1/ko active IP Right Grant
- 2005-05-02 BR BRPI0511138-2A patent/BRPI0511138A/pt not_active IP Right Cessation
- 2005-05-02 CN CNA2005800155302A patent/CN1953974A/zh active Pending
- 2005-05-02 AU AU2005243397A patent/AU2005243397A1/en not_active Abandoned
- 2005-05-02 GE GEAP20059703A patent/GEP20104875B/en unknown
- 2005-05-02 EA EA200601796A patent/EA200601796A1/ru unknown
- 2005-05-02 CA CA002566707A patent/CA2566707A1/en not_active Abandoned
- 2005-05-11 TW TW094115237A patent/TWI303635B/zh active
- 2005-05-11 PA PA20058632601A patent/PA8632601A1/es unknown
- 2005-05-12 UY UY28894A patent/UY28894A1/es not_active Application Discontinuation
- 2005-05-12 PE PE2005000534A patent/PE20060240A1/es not_active Application Discontinuation
- 2005-05-13 AR ARP050101969A patent/AR049097A1/es not_active Application Discontinuation
- 2005-05-13 GT GT200500113A patent/GT200500113A/es unknown
- 2005-05-13 NL NL1029045A patent/NL1029045C2/nl active Search and Examination
-
2006
- 2006-05-19 NL NL1031845A patent/NL1031845C2/nl active Search and Examination
- 2006-10-06 ZA ZA200608394A patent/ZA200608394B/xx unknown
- 2006-10-09 NO NO20064576A patent/NO20064576L/no not_active Application Discontinuation
- 2006-10-23 IL IL178828A patent/IL178828A0/en unknown
- 2006-11-13 TN TNP2006000370A patent/TNSN06370A1/fr unknown
- 2006-11-13 EC EC2006006997A patent/ECSP066997A/es unknown
- 2006-11-13 CR CR8749A patent/CR8749A/es not_active Application Discontinuation
- 2006-11-14 MA MA29452A patent/MA28583B1/fr unknown
-
2009
- 2009-11-13 AU AU2009238255A patent/AU2009238255A1/en not_active Ceased
Also Published As
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Legal Events
Date | Code | Title | Description |
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AD1A | A request for search or an international type search has been filed | ||
PD2A | A request for search or an international type search has been filed |