NL1031845A1 - Pyrimidine derivatives for the treatment of abnormal cell growth. - Google Patents
Pyrimidine derivatives for the treatment of abnormal cell growth.Info
- Publication number
- NL1031845A1 NL1031845A1 NL1031845A NL1031845A NL1031845A1 NL 1031845 A1 NL1031845 A1 NL 1031845A1 NL 1031845 A NL1031845 A NL 1031845A NL 1031845 A NL1031845 A NL 1031845A NL 1031845 A1 NL1031845 A1 NL 1031845A1
- Authority
- NL
- Netherlands
- Prior art keywords
- treatment
- cell growth
- abnormal cell
- pyrimidine derivatives
- pyrimidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57131204P | 2004-05-14 | 2004-05-14 | |
| US57131204 | 2004-05-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL1031845A1 true NL1031845A1 (en) | 2006-07-31 |
| NL1031845C2 NL1031845C2 (en) | 2006-11-23 |
Family
ID=34966230
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1029045A NL1029045C2 (en) | 2004-05-14 | 2005-05-13 | Pyrimidine derivatives for the treatment of abnormal cell growth. |
| NL1031845A NL1031845C2 (en) | 2004-05-14 | 2006-05-19 | Pyrimidine derivatives for the treatment of abnormal cell growth. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL1029045A NL1029045C2 (en) | 2004-05-14 | 2005-05-13 | Pyrimidine derivatives for the treatment of abnormal cell growth. |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1751143A1 (en) |
| JP (1) | JP4099212B2 (en) |
| KR (1) | KR100886990B1 (en) |
| CN (2) | CN102127058A (en) |
| AP (1) | AP2241A (en) |
| AR (1) | AR049097A1 (en) |
| AU (2) | AU2005243397A1 (en) |
| BR (1) | BRPI0511138A (en) |
| CA (1) | CA2566707A1 (en) |
| CR (1) | CR8749A (en) |
| EA (1) | EA200601796A1 (en) |
| EC (1) | ECSP066997A (en) |
| GE (1) | GEP20104875B (en) |
| GT (1) | GT200500113A (en) |
| IL (1) | IL178828A0 (en) |
| MA (1) | MA28583B1 (en) |
| MX (1) | MXPA06011890A (en) |
| NL (2) | NL1029045C2 (en) |
| NO (1) | NO20064576L (en) |
| NZ (1) | NZ550448A (en) |
| PA (1) | PA8632601A1 (en) |
| PE (1) | PE20060240A1 (en) |
| TN (1) | TNSN06370A1 (en) |
| TW (1) | TWI303635B (en) |
| UY (1) | UY28894A1 (en) |
| WO (1) | WO2005111023A1 (en) |
| ZA (1) | ZA200608394B (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1763514A2 (en) * | 2004-05-18 | 2007-03-21 | Rigel Pharmaceuticals, Inc. | Cycloalkyl substituted pyrimidinediamine compounds and their uses |
| US20070032514A1 (en) * | 2005-07-01 | 2007-02-08 | Zahn Stephan K | 2,4-diamino-pyrimidines as aurora inhibitors |
| EA014551B1 (en) * | 2005-12-21 | 2010-12-30 | Пфайзер Продактс Инк. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| ES2593486T3 (en) * | 2007-04-18 | 2016-12-09 | Pfizer Products Inc. | Sulfonyl amide derivatives for the treatment of abnormal cell growth |
| CA2693594A1 (en) * | 2007-07-17 | 2009-01-22 | Rigel Pharmaceuticals, Inc. | Cyclic amine substituted pyrimidinediamines as pkc inhibitors |
| WO2009071535A1 (en) * | 2007-12-03 | 2009-06-11 | Boehringer Ingelheim International Gmbh | Diaminopyridines for the treatment of diseases which are characterised by excessive or anomal cell proliferation |
| CN102105150B (en) * | 2008-05-21 | 2014-03-12 | 阿里亚德医药股份有限公司 | Phosphorous derivatives as kinase inhibitors |
| US8410126B2 (en) * | 2009-05-29 | 2013-04-02 | Boehringer Ingelheim International Gmbh | Pyrimidine inhibitors of PKTK2 |
| WO2011018517A1 (en) | 2009-08-14 | 2011-02-17 | Boehringer Ingelheim International Gmbh | Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives |
| US8933227B2 (en) | 2009-08-14 | 2015-01-13 | Boehringer Ingelheim International Gmbh | Selective synthesis of functionalized pyrimidines |
| US20120244141A1 (en) | 2010-09-28 | 2012-09-27 | Boehringer Ingelheim International Gmbh | Stratification of cancer patients for susceptibility to therapy with PTK2 inhibitors |
| WO2014174745A1 (en) * | 2013-04-26 | 2014-10-30 | 国立大学法人京都大学 | Eg5 INHIBITOR |
| CN109608444B (en) * | 2018-11-27 | 2022-02-11 | 中国药科大学 | Isoindolinone-containing ERK inhibitor and preparation method and application thereof |
| CN111732548B (en) * | 2020-06-11 | 2022-06-17 | 浙江大学 | N2-carbamyl aromatic ring-2-aminopyrimidine derivatives and medical application thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9721437D0 (en) * | 1997-10-10 | 1997-12-10 | Glaxo Group Ltd | Heteroaromatic compounds and their use in medicine |
| AR042586A1 (en) | 2001-02-15 | 2005-06-29 | Sugen Inc | 3- (4-AMIDOPIRROL-2-ILMETILIDEN) -2-INDOLINONE AS INHIBITORS OF PROTEIN KINASE; YOUR PHARMACEUTICAL COMPOSITIONS; A METHOD FOR THE MODULATION OF THE CATALYTIC ACTIVITY OF PROTEINQUINASE; A METHOD TO TREAT OR PREVENT AN AFFECTION RELATED TO PROTEINQUINASE |
| WO2003030909A1 (en) | 2001-09-25 | 2003-04-17 | Bayer Pharmaceuticals Corporation | 2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer |
| UA80767C2 (en) * | 2002-12-20 | 2007-10-25 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| CA2529611C (en) * | 2002-12-20 | 2009-12-15 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
-
2005
- 2005-05-02 AP AP2006003790A patent/AP2241A/en active
- 2005-05-02 CN CN2011100212904A patent/CN102127058A/en active Pending
- 2005-05-02 JP JP2007512557A patent/JP4099212B2/en active Active
- 2005-05-02 CA CA002566707A patent/CA2566707A1/en not_active Abandoned
- 2005-05-02 KR KR1020067023767A patent/KR100886990B1/en active IP Right Grant
- 2005-05-02 NZ NZ550448A patent/NZ550448A/en unknown
- 2005-05-02 GE GEAP20059703A patent/GEP20104875B/en unknown
- 2005-05-02 EA EA200601796A patent/EA200601796A1/en unknown
- 2005-05-02 CN CNA2005800155302A patent/CN1953974A/en active Pending
- 2005-05-02 EP EP05732043A patent/EP1751143A1/en not_active Withdrawn
- 2005-05-02 WO PCT/IB2005/001201 patent/WO2005111023A1/en active Application Filing
- 2005-05-02 BR BRPI0511138-2A patent/BRPI0511138A/en not_active IP Right Cessation
- 2005-05-02 AU AU2005243397A patent/AU2005243397A1/en not_active Abandoned
- 2005-05-02 MX MXPA06011890A patent/MXPA06011890A/en unknown
- 2005-05-11 TW TW094115237A patent/TWI303635B/en active
- 2005-05-11 PA PA20058632601A patent/PA8632601A1/en unknown
- 2005-05-12 UY UY28894A patent/UY28894A1/en not_active Application Discontinuation
- 2005-05-12 PE PE2005000534A patent/PE20060240A1/en not_active Application Discontinuation
- 2005-05-13 NL NL1029045A patent/NL1029045C2/en active Search and Examination
- 2005-05-13 AR ARP050101969A patent/AR049097A1/en not_active Application Discontinuation
- 2005-05-13 GT GT200500113A patent/GT200500113A/en unknown
-
2006
- 2006-05-19 NL NL1031845A patent/NL1031845C2/en active Search and Examination
- 2006-10-06 ZA ZA200608394A patent/ZA200608394B/en unknown
- 2006-10-09 NO NO20064576A patent/NO20064576L/en not_active Application Discontinuation
- 2006-10-23 IL IL178828A patent/IL178828A0/en unknown
- 2006-11-13 TN TNP2006000370A patent/TNSN06370A1/en unknown
- 2006-11-13 CR CR8749A patent/CR8749A/en not_active Application Discontinuation
- 2006-11-13 EC EC2006006997A patent/ECSP066997A/en unknown
- 2006-11-14 MA MA29452A patent/MA28583B1/en unknown
-
2009
- 2009-11-13 AU AU2009238255A patent/AU2009238255A1/en not_active Ceased
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL2000375A1 (en) | Pyrimidine derivatives for the treatment of abnormal cell growth. | |
| NL1029045A1 (en) | Pyrimidine derivatives for the treatment of abnormal cell growth. | |
| NL1025067A1 (en) | Pyrimidine derivatives for the treatment of abnormal cell growth. | |
| NL1025071A1 (en) | Compounds for the treatment of abnormal cell growth. | |
| NL1028086A1 (en) | Sulphonamide derivatives for the treatment of diseases. | |
| NL1028087A1 (en) | Sulfonamide derivatives for the treatment of diseases. | |
| NL1026329A1 (en) | 2-Amino-pyridine derivatives useful for the treatment of diseases. | |
| NL1028599A1 (en) | Compounds for the treatment of diseases. | |
| WO2006124713A3 (en) | 4-biarylyl-1-phenylazetidin-2-ones | |
| WO2006078287A3 (en) | Pde4b inhibitors and uses therefor | |
| DK1633726T3 (en) | Pyrimidine derivatives suitable for the treatment of CRTH2-mediated diseases | |
| NL1028598A1 (en) | Imidazole compounds for the treatment of neurodegenerative diseases. | |
| NL2000323A1 (en) | Pyrimidine derivatives. | |
| NL1026327A1 (en) | 2-Amino-pyridine derivatives useful for the treatment of diseases. | |
| HK1118556A1 (en) | 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives | |
| NO20053483D0 (en) | 4-Anilinoquinazoline derivatives for the treatment of abnormal cell growth | |
| NL1026203A1 (en) | Compounds useful for the treatment of diseases. | |
| DE602006003094D1 (en) | 4-PHENYL-5-OXO-1,4,5,6,7,8-HEXAHYDROCHINOLINE DERIVATIVES FOR THE TREATMENT OF BARRENESS | |
| NL1033562A1 (en) | Tetrahydropyridoazepine-8-ones and related compounds for the treatment of schizophrenia. | |
| WO2006081337A3 (en) | Erastin analogues and their uses for killing cancer cells | |
| NL1032552C2 (en) | Imidazole compounds for the treatment of neurological disorders. | |
| FR2873372B1 (en) | PROCESS FOR THE PREPARATION OF N-PIPERIDINO-1,5-DIPHENYLPYRAZOLE-3-CARBOXAMIDE DERIVATIVES | |
| WO2007060458A3 (en) | Treatment of ophthalmic diseases with beta-amino alcohols | |
| NL2000255A1 (en) | Inhibitors of the HIV integrase enzyme. | |
| NL1028597A1 (en) | Formamide derivatives for the treatment of diseases. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AD1A | A request for search or an international type search has been filed | ||
| PD2A | A request for search or an international type search has been filed |