NL1026091C2 - PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. - Google Patents

PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. Download PDF

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Publication number
NL1026091C2
NL1026091C2 NL1026091A NL1026091A NL1026091C2 NL 1026091 C2 NL1026091 C2 NL 1026091C2 NL 1026091 A NL1026091 A NL 1026091A NL 1026091 A NL1026091 A NL 1026091A NL 1026091 C2 NL1026091 C2 NL 1026091C2
Authority
NL
Netherlands
Prior art keywords
dihydro
pyrazolo
ethoxy
benzyl
oxo
Prior art date
Application number
NL1026091A
Other languages
English (en)
Dutch (nl)
Other versions
NL1026091A1 (nl
Inventor
Michael Scott Visser
Andrew Simon Bell
Michael Paul Deninno
Michael John Palmer
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NL1026091A1 publication Critical patent/NL1026091A1/nl
Application granted granted Critical
Publication of NL1026091C2 publication Critical patent/NL1026091C2/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL1026091A 2003-04-30 2004-04-29 PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. NL1026091C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46663903P 2003-04-30 2003-04-30
US46663903 2003-04-30

Publications (2)

Publication Number Publication Date
NL1026091A1 NL1026091A1 (nl) 2004-11-02
NL1026091C2 true NL1026091C2 (nl) 2005-05-26

Family

ID=33551403

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1026091A NL1026091C2 (nl) 2003-04-30 2004-04-29 PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte.

Country Status (8)

Country Link
AR (1) AR044119A1 (es)
CL (1) CL2004000901A1 (es)
GT (1) GT200400086A (es)
NL (1) NL1026091C2 (es)
PA (1) PA8601601A1 (es)
PE (1) PE20050466A1 (es)
TW (1) TW200503714A (es)
UY (1) UY28291A1 (es)

Also Published As

Publication number Publication date
UY28291A1 (es) 2004-11-30
GT200400086A (es) 2005-01-11
TW200503714A (en) 2005-02-01
AR044119A1 (es) 2005-08-24
CL2004000901A1 (es) 2005-03-18
NL1026091A1 (nl) 2004-11-02
PE20050466A1 (es) 2005-06-18
PA8601601A1 (es) 2005-02-04

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Legal Events

Date Code Title Description
AD1A A request for search or an international type search has been filed
RD2N Patents in respect of which a decision has been taken or a report has been made (novelty report)

Effective date: 20050125

PD2B A search report has been drawn up
VD1 Lapsed due to non-payment of the annual fee

Effective date: 20081101