NL1026091C2 - PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. - Google Patents
PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. Download PDFInfo
- Publication number
- NL1026091C2 NL1026091C2 NL1026091A NL1026091A NL1026091C2 NL 1026091 C2 NL1026091 C2 NL 1026091C2 NL 1026091 A NL1026091 A NL 1026091A NL 1026091 A NL1026091 A NL 1026091A NL 1026091 C2 NL1026091 C2 NL 1026091C2
- Authority
- NL
- Netherlands
- Prior art keywords
- dihydro
- pyrazolo
- ethoxy
- benzyl
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46663903P | 2003-04-30 | 2003-04-30 | |
US46663903 | 2003-04-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
NL1026091A1 NL1026091A1 (nl) | 2004-11-02 |
NL1026091C2 true NL1026091C2 (nl) | 2005-05-26 |
Family
ID=33551403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1026091A NL1026091C2 (nl) | 2003-04-30 | 2004-04-29 | PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. |
Country Status (8)
Country | Link |
---|---|
AR (1) | AR044119A1 (es) |
CL (1) | CL2004000901A1 (es) |
GT (1) | GT200400086A (es) |
NL (1) | NL1026091C2 (es) |
PA (1) | PA8601601A1 (es) |
PE (1) | PE20050466A1 (es) |
TW (1) | TW200503714A (es) |
UY (1) | UY28291A1 (es) |
-
2004
- 2004-04-27 PA PA20048601601A patent/PA8601601A1/es unknown
- 2004-04-27 PE PE2004000413A patent/PE20050466A1/es not_active Application Discontinuation
- 2004-04-27 UY UY28291A patent/UY28291A1/es not_active Application Discontinuation
- 2004-04-28 AR ARP040101447A patent/AR044119A1/es unknown
- 2004-04-28 CL CL200400901A patent/CL2004000901A1/es unknown
- 2004-04-29 GT GT200400086A patent/GT200400086A/es unknown
- 2004-04-29 TW TW093112075A patent/TW200503714A/zh unknown
- 2004-04-29 NL NL1026091A patent/NL1026091C2/nl not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
UY28291A1 (es) | 2004-11-30 |
GT200400086A (es) | 2005-01-11 |
TW200503714A (en) | 2005-02-01 |
AR044119A1 (es) | 2005-08-24 |
CL2004000901A1 (es) | 2005-03-18 |
NL1026091A1 (nl) | 2004-11-02 |
PE20050466A1 (es) | 2005-06-18 |
PA8601601A1 (es) | 2005-02-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20040220186A1 (en) | PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease | |
EP3350170B1 (en) | Heteroaryl compounds as irak inhibitors and uses thereof | |
AU2023202058A1 (en) | sGC Stimulators | |
AU2019249721B2 (en) | Heteroaryl compounds as type II IRAK inhibitors and uses hereof | |
EP2897953B1 (en) | Sgc stimulators | |
EP2518067B1 (fr) | Dérives de n-[(1h-pyrazol-1-yl)aryl]-1h-indole ou 1h- indazole-3-carboxamide et leurs applications en thérapeutique comme antagonistes de p2y12. | |
JP5227032B2 (ja) | プロテインキナーゼの阻害剤として有用なピロロピリミジン | |
RU2443700C2 (ru) | Диаминотриазольные соединения, применяемые в качестве ингибиторов протеиновой киназы | |
EP3253763B1 (en) | Pyridazinone macrocycles as irak inhibitors and uses thereof | |
US20030195205A1 (en) | PDE9 inhibitors for treating cardiovascular disorders | |
EP1440073A1 (en) | Pde9 inhibitors for treating cardiovascular disorders | |
CA2933250A1 (en) | Sgc stimulators | |
CZ20022933A3 (cs) | 1,5-Disubstituované-3,4-dihydro-1H-pyrimido [4,5-D] pyrimidin-2-onové sloučeniny a jejich použití při léčbě nemocí zprostředkovaných CSBP/P38 kinasou | |
NZ732538A (en) | Macrocyclic compounds as irak1/4 inhibitors and uses thereof | |
JP6916171B2 (ja) | ヒト血漿カリクレイン阻害剤 | |
HUE032273T2 (en) | 3-Imidazolyl-pyrazolo [3,4-b] pyridines | |
BRPI0918517B1 (pt) | composto, composição farmacêutica, e, uso de um composto | |
BRPI0618284A2 (pt) | derivado de pirazolo-[4,3-d]-pirimidin-5-il usado como inibidores de pde5 | |
WO2022197755A1 (en) | Imidazopyridinyl inhibitors of plasma kallikrein | |
NL1026091C2 (nl) | PDE9-remmers voor de behandeling van type 2 diabetes, metabolisch syndroom en cardiovasculaire ziekte. | |
US20240199612A1 (en) | Imidazopyridinyl inhibitors of plasma kallikrein | |
EA045195B1 (ru) | Конденсированные пирролины, которые действуют как ингибиторы убиквитин-специфической протеазы 30 (usp30) | |
EA047746B1 (ru) | Конденсированные бициклические стимуляторы sgc |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AD1A | A request for search or an international type search has been filed | ||
RD2N | Patents in respect of which a decision has been taken or a report has been made (novelty report) |
Effective date: 20050125 |
|
PD2B | A search report has been drawn up | ||
VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20081101 |