NL1001348C2 - Polypeptide comprising glycosyl-phosphatidyl:inositol structure - Google Patents
Polypeptide comprising glycosyl-phosphatidyl:inositol structureInfo
- Publication number
- NL1001348C2 NL1001348C2 NL1001348A NL1001348A NL1001348C2 NL 1001348 C2 NL1001348 C2 NL 1001348C2 NL 1001348 A NL1001348 A NL 1001348A NL 1001348 A NL1001348 A NL 1001348A NL 1001348 C2 NL1001348 C2 NL 1001348C2
- Authority
- NL
- Netherlands
- Prior art keywords
- polypeptide
- recombinant
- glycosyl
- phosphatidyl
- sequence
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical group O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 229930004094 glycosylphosphatidylinositol Natural products 0.000 abstract 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 1
- 241000168726 Dictyostelium discoideum Species 0.000 abstract 1
- 229930186217 Glycolipid Natural products 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 230000005026 transcription initiation Effects 0.000 abstract 1
- 230000005030 transcription termination Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/428,616 US6113917A (en) | 1995-04-25 | 1995-04-25 | Modified polypeptides for enhanced immunogenicity |
IL11802196A IL118021A0 (en) | 1995-04-25 | 1996-04-23 | Modified polypeptides for enhanced immunogenicity |
HU9802238A HUP9802238A3 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides for enhanced immunogenicity |
AU56481/96A AU714808B2 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides for enhanced immunogenicity |
EP96913528A EP0826050A1 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides for enhanced immunogenicity |
CZ19973378A CZ291013B6 (cs) | 1995-04-25 | 1996-04-25 | Modifikované polypeptidy vykazující zvýąenou imunogenitu |
PL96323078A PL323078A1 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides of enchanced immunogenecity |
PCT/EP1996/001744 WO1996034105A1 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides for enhanced immunogenicity |
JP8532179A JPH11504215A (ja) | 1995-04-25 | 1996-04-25 | 免疫原性の高められた修飾ポリペプチド |
NZ335929A NZ335929A (en) | 1995-04-25 | 1996-04-25 | Use of a recombinant polypeptide having a glycosyl-phosphatidylinositol anchor for inducing an immune response |
NZ307195A NZ307195A (en) | 1995-04-25 | 1996-04-25 | Recombinant polypeptides containing a glycosyl-phosphatidylinositol anchor having enhanced immunogencity against parasites |
BR9604989-8A BR9604989A (pt) | 1995-04-25 | 1996-04-25 | Polipeptídeos modificados para imunogenicidade aperfeiçoada e processo de sua produção |
CA002218987A CA2218987A1 (en) | 1995-04-25 | 1996-04-25 | Modified polypeptides for enhanced immunogenicity |
NO974924A NO974924L (no) | 1995-04-25 | 1997-10-24 | Modifiserte polypeptider med öket immunogenisitet |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/428,616 US6113917A (en) | 1995-04-25 | 1995-04-25 | Modified polypeptides for enhanced immunogenicity |
EP95201066 | 1995-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
NL1001348C2 true NL1001348C2 (en) | 1996-10-28 |
Family
ID=26139248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL1001348A NL1001348C2 (en) | 1995-04-25 | 1995-10-05 | Polypeptide comprising glycosyl-phosphatidyl:inositol structure |
Country Status (15)
Country | Link |
---|---|
US (1) | US6113917A (ja) |
EP (1) | EP0826050A1 (ja) |
JP (1) | JPH11504215A (ja) |
AU (1) | AU714808B2 (ja) |
BR (1) | BR9604989A (ja) |
CA (1) | CA2218987A1 (ja) |
CZ (1) | CZ291013B6 (ja) |
HU (1) | HUP9802238A3 (ja) |
IL (1) | IL118021A0 (ja) |
NL (1) | NL1001348C2 (ja) |
NO (1) | NO974924L (ja) |
NZ (1) | NZ307195A (ja) |
PL (1) | PL323078A1 (ja) |
WO (1) | WO1996034105A1 (ja) |
ZA (1) | ZA963269B (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997026911A1 (en) * | 1996-01-29 | 1997-07-31 | Georgetown University | Malaria vaccine based upon the addition of a msa1 peptide |
AUPP589398A0 (en) * | 1998-09-14 | 1998-10-08 | Walter And Eliza Hall Institute Of Medical Research, The | Immunogenic compositions and uses thereof |
AUPP675898A0 (en) * | 1998-10-27 | 1998-11-19 | Walter And Eliza Hall Institute Of Medical Research, The | A method of activating t cells and agents useful for same |
KR20050035511A (ko) * | 2001-10-13 | 2005-04-18 | 아스테리온 리미티드 | 폴리펩타이드들을 포함하는 글리코실포스파티딜이노시톨 |
US20030171260A1 (en) * | 2002-03-11 | 2003-09-11 | Nelson Deanna Jean | Compositions and methods utilizing hydroxamates to scavenge oxidant toxins |
BR0312985A (pt) | 2002-07-26 | 2005-06-21 | Inst Medical W & E Hall | Métodos para extrair ou induzir, em um mamìfero, uma resposta imune dirigida a um parasita, para tratar de modo terapêutico ou profilático um mamìfero para infecção por parasitas, para o tratamento e/ou a profilaxia de uma condição doentia de mamìfero, uso de uma composição,composição, composição de vacina, composição farmacêutica, anticorpo para inibir, parar ou retardar o inìcio ou progressão de uma condição doentia de mamìfero, uso de um anticorpo, métodos para detectar, em uma amostra bológica, uma molécula imunointerativa dirigida a um microorganismo e para detectar, monitorar ou de outra forma avaliar uma resposta imune dirigida a um microorganismo em um indivìduo, kit modular, método para analisar, projetar e/ou modificar um agente capaz de interagir com um sìtio de ligação de molécula imunointerativa anti-gpi glicano, e, uso do agente |
WO2004090135A2 (en) * | 2003-04-09 | 2004-10-21 | Asterion Limited | Cytokine polypeptides and antibodies containing a signal sequence for the attachement of glycosylphosphatidylinositol |
US20080026008A1 (en) * | 2006-07-27 | 2008-01-31 | Clark Tibbs | Bacteriophage DNA vaccine vector |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992020806A2 (en) * | 1991-05-17 | 1992-11-26 | Rmf Dictagene S.A. | Dictyostelid expression vector and method for expressing a desired protein |
WO1995022614A1 (en) * | 1994-02-17 | 1995-08-24 | Finep-Financiadora De Estudos E Projetos | Production of glycosylphosphatidylinositol-anchored recombinant proteins |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8905857D0 (en) * | 1989-03-14 | 1989-04-26 | Hoffmann La Roche | Plasmodium merozoite rhoptries antigen |
-
1995
- 1995-04-25 US US08/428,616 patent/US6113917A/en not_active Expired - Fee Related
- 1995-10-05 NL NL1001348A patent/NL1001348C2/xx not_active IP Right Cessation
-
1996
- 1996-04-23 IL IL11802196A patent/IL118021A0/xx unknown
- 1996-04-24 ZA ZA963269A patent/ZA963269B/xx unknown
- 1996-04-25 AU AU56481/96A patent/AU714808B2/en not_active Ceased
- 1996-04-25 HU HU9802238A patent/HUP9802238A3/hu unknown
- 1996-04-25 CZ CZ19973378A patent/CZ291013B6/cs not_active IP Right Cessation
- 1996-04-25 WO PCT/EP1996/001744 patent/WO1996034105A1/en not_active Application Discontinuation
- 1996-04-25 BR BR9604989-8A patent/BR9604989A/pt not_active Application Discontinuation
- 1996-04-25 NZ NZ307195A patent/NZ307195A/xx unknown
- 1996-04-25 PL PL96323078A patent/PL323078A1/xx unknown
- 1996-04-25 JP JP8532179A patent/JPH11504215A/ja not_active Ceased
- 1996-04-25 EP EP96913528A patent/EP0826050A1/en not_active Withdrawn
- 1996-04-25 CA CA002218987A patent/CA2218987A1/en not_active Abandoned
-
1997
- 1997-10-24 NO NO974924A patent/NO974924L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992020806A2 (en) * | 1991-05-17 | 1992-11-26 | Rmf Dictagene S.A. | Dictyostelid expression vector and method for expressing a desired protein |
WO1995022614A1 (en) * | 1994-02-17 | 1995-08-24 | Finep-Financiadora De Estudos E Projetos | Production of glycosylphosphatidylinositol-anchored recombinant proteins |
Non-Patent Citations (3)
Title |
---|
PEARCE E. J. ET AL.: "Three major surface antigens of Schistosoma mansoni are linked to the membrane by glycosylphosphatidylinositol", JOURNAL OF IMMUNOLOGY, vol. 142, no. 3, 1 February 1989 (1989-02-01), BALTIMORE US, pages 979 - 984 * |
REYMOND C D ET AL: "Anchoring of an immunogenic Plasmodium falciparum circumsporozoite protein on the surface of Dictyostelium discoideum.", JOURNAL OF BIOLOGICAL CHEMISTRY 270 (21). 1995. 12941-12947 * |
VAI M ET AL: "ISOLATION AND DEDUCED AMINO ACID SEQUENCE OF THE GENE ENCODING GP115 A YEAST GLYCOPHOSPHOLIPID-ANCHORED PROTEIN CONTAINING A SERINE-RICH REGION.", J BIOL CHEM 266 (19). 1991. 12242-12248 * |
Also Published As
Publication number | Publication date |
---|---|
HUP9802238A2 (hu) | 1999-01-28 |
JPH11504215A (ja) | 1999-04-20 |
NO974924D0 (no) | 1997-10-24 |
CZ291013B6 (cs) | 2002-11-13 |
BR9604989A (pt) | 1999-11-30 |
AU714808B2 (en) | 2000-01-13 |
NZ307195A (en) | 1999-07-29 |
NO974924L (no) | 1997-12-19 |
AU5648196A (en) | 1996-11-18 |
IL118021A0 (en) | 1996-08-04 |
PL323078A1 (en) | 1998-03-02 |
ZA963269B (en) | 1996-10-25 |
CZ337897A3 (cs) | 1998-04-15 |
WO1996034105A1 (en) | 1996-10-31 |
CA2218987A1 (en) | 1996-10-31 |
HUP9802238A3 (en) | 2000-03-28 |
EP0826050A1 (en) | 1998-03-04 |
US6113917A (en) | 2000-09-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PD2B | A search report has been drawn up | ||
VD1 | Lapsed due to non-payment of the annual fee |
Effective date: 20060501 |