MY8500975A - Indole and indoline derivatives - Google Patents
Indole and indoline derivativesInfo
- Publication number
- MY8500975A MY8500975A MY975/85A MY8500975A MY8500975A MY 8500975 A MY8500975 A MY 8500975A MY 975/85 A MY975/85 A MY 975/85A MY 8500975 A MY8500975 A MY 8500975A MY 8500975 A MY8500975 A MY 8500975A
- Authority
- MY
- Malaysia
- Prior art keywords
- carbon atoms
- alkyl
- hydrogen
- indole
- indoline derivatives
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title abstract 4
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 title abstract 2
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 title abstract 2
- 125000003387 indolinyl group Chemical class N1(CCC2=CC=CC=C12)* 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5456—Arylalkanephosphonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8019948 | 1980-06-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY8500975A true MY8500975A (en) | 1985-12-31 |
Family
ID=10514138
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MY975/85A MY8500975A (en) | 1980-06-18 | 1985-12-30 | Indole and indoline derivatives |
| MY409/86A MY8600409A (en) | 1980-06-18 | 1986-12-30 | Indole and indoline derivatives |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MY409/86A MY8600409A (en) | 1980-06-18 | 1986-12-30 | Indole and indoline derivatives |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4493843A (fi) |
| EP (1) | EP0042298B1 (fi) |
| JP (1) | JPS5728048A (fi) |
| KR (1) | KR850001470B1 (fi) |
| AT (1) | ATE9329T1 (fi) |
| AU (1) | AU539678B2 (fi) |
| CA (1) | CA1149811A (fi) |
| DE (1) | DE3165998D1 (fi) |
| DK (1) | DK264281A (fi) |
| ES (4) | ES8300091A1 (fi) |
| FI (1) | FI811889L (fi) |
| GB (1) | GB2078736B (fi) |
| GR (1) | GR75701B (fi) |
| HK (2) | HK92684A (fi) |
| HU (1) | HU183480B (fi) |
| IE (1) | IE52102B1 (fi) |
| IL (1) | IL63110A (fi) |
| MY (2) | MY8500975A (fi) |
| NZ (1) | NZ197441A (fi) |
| PH (1) | PH16357A (fi) |
| SG (2) | SG68984G (fi) |
| ZA (1) | ZA814057B (fi) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1114028B1 (en) | 1998-08-26 | 2006-11-29 | Aventis Pharma Limited | Aza-bicycles which modulate the inhibition of cell adhesion |
| AU2050001A (en) * | 1999-12-16 | 2001-06-25 | Eli Lilly And Company | Synthesis of indole-containing spla2 inhibitors |
| WO2003099789A1 (en) | 2002-05-22 | 2003-12-04 | Errant Gene Therapeutics, Llc. | Histone deacetylase inhibitors based on alphachalcogenmethylcarbonyl compounds |
| JP2007529523A (ja) * | 2004-03-15 | 2007-10-25 | イーライ リリー アンド カンパニー | 肥満症を治療するためのオピオイド受容体拮抗物質としての４−（５−アミノメチル）−インドール−１−イルメチル）−ベンズアミド誘導体および関連化合物 |
| JP6217561B2 (ja) * | 2014-08-21 | 2017-10-25 | 信越化学工業株式会社 | 新規オニウム塩化合物及びレジスト組成物並びにパターン形成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3076814A (en) * | 1954-04-28 | 1963-02-05 | Upjohn Co | Novel process for the preparation of tryptophols and to novel compounds produced therein |
| DE2237361A1 (de) * | 1972-07-29 | 1974-02-14 | Boehringer Mannheim Gmbh | (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben |
| US3901899A (en) * | 1973-04-27 | 1975-08-26 | Univ Ohio State Res Found | Synthesis of indoles from anilines and intermediates therein |
| US3992392A (en) * | 1973-04-27 | 1976-11-16 | The Ohio State University Research Foundation | Synthesis of indoles from anilines and intermediates therein |
| US3950343A (en) * | 1973-11-06 | 1976-04-13 | Ayerst, Mckenna And Harrison Ltd. | Pyrroloisoquinoline derivatives |
| FI59246C (fi) * | 1974-06-24 | 1981-07-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin |
| DE2909779A1 (de) * | 1979-03-13 | 1980-09-18 | Thomae Gmbh Dr K | Neue indolderivate, deren herstellung und deren verwendung als arzneimittel |
-
1981
- 1981-06-16 DK DK264281A patent/DK264281A/da not_active Application Discontinuation
- 1981-06-16 DE DE8181302699T patent/DE3165998D1/de not_active Expired
- 1981-06-16 HU HU811777A patent/HU183480B/hu unknown
- 1981-06-16 ES ES503097A patent/ES8300091A1/es not_active Expired
- 1981-06-16 AU AU71864/81A patent/AU539678B2/en not_active Ceased
- 1981-06-16 AT AT81302699T patent/ATE9329T1/de not_active IP Right Cessation
- 1981-06-16 FI FI811889A patent/FI811889L/fi not_active Application Discontinuation
- 1981-06-16 GB GB8118439A patent/GB2078736B/en not_active Expired
- 1981-06-16 KR KR1019810002197A patent/KR850001470B1/ko active
- 1981-06-16 ZA ZA814057A patent/ZA814057B/xx unknown
- 1981-06-16 NZ NZ197441A patent/NZ197441A/en unknown
- 1981-06-16 EP EP81302699A patent/EP0042298B1/en not_active Expired
- 1981-06-17 PH PH25767A patent/PH16357A/en unknown
- 1981-06-17 CA CA000380032A patent/CA1149811A/en not_active Expired
- 1981-06-17 IL IL63110A patent/IL63110A/xx unknown
- 1981-06-17 GR GR65248A patent/GR75701B/el unknown
- 1981-06-17 IE IE1344/81A patent/IE52102B1/en unknown
- 1981-06-18 JP JP9453481A patent/JPS5728048A/ja active Pending
-
1982
- 1982-05-21 US US06/380,838 patent/US4493843A/en not_active Expired - Fee Related
- 1982-05-31 ES ES512706A patent/ES8305327A1/es not_active Expired
- 1982-05-31 ES ES512704A patent/ES512704A0/es active Granted
- 1982-05-31 ES ES512705A patent/ES512705A0/es active Granted
-
1984
- 1984-09-25 SG SG689/84A patent/SG68984G/en unknown
- 1984-11-22 HK HK926/84A patent/HK92684A/xx unknown
-
1985
- 1985-10-05 SG SG730/85A patent/SG73085G/en unknown
- 1985-11-21 HK HK924/85A patent/HK92485A/xx unknown
- 1985-12-30 MY MY975/85A patent/MY8500975A/xx unknown
-
1986
- 1986-12-30 MY MY409/86A patent/MY8600409A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE811344L (en) | 1981-12-18 |
| SG68984G (en) | 1985-03-15 |
| ES503097A0 (es) | 1982-10-01 |
| ES512706A0 (es) | 1983-04-01 |
| DE3165998D1 (de) | 1984-10-18 |
| FI811889L (fi) | 1981-12-19 |
| GR75701B (fi) | 1984-08-02 |
| ES8303333A1 (es) | 1983-02-01 |
| EP0042298B1 (en) | 1984-09-12 |
| SG73085G (en) | 1986-05-02 |
| ES8303332A1 (es) | 1983-02-01 |
| MY8600409A (en) | 1986-12-31 |
| DK264281A (da) | 1981-12-19 |
| ES512705A0 (es) | 1983-02-01 |
| US4493843A (en) | 1985-01-15 |
| PH16357A (en) | 1983-09-05 |
| HK92684A (en) | 1984-11-30 |
| ES8300091A1 (es) | 1982-10-01 |
| GB2078736A (en) | 1982-01-13 |
| CA1149811A (en) | 1983-07-12 |
| ZA814057B (en) | 1982-07-28 |
| ES512704A0 (es) | 1983-02-01 |
| IE52102B1 (en) | 1987-06-24 |
| IL63110A (en) | 1986-10-31 |
| GB2078736B (en) | 1984-03-07 |
| HK92485A (en) | 1985-11-29 |
| ES8305327A1 (es) | 1983-04-01 |
| AU539678B2 (en) | 1984-10-11 |
| JPS5728048A (en) | 1982-02-15 |
| ATE9329T1 (de) | 1984-09-15 |
| AU7186481A (en) | 1981-12-24 |
| KR850001470B1 (ko) | 1985-10-10 |
| HU183480B (en) | 1984-05-28 |
| NZ197441A (en) | 1984-11-09 |
| KR830006205A (ko) | 1983-09-20 |
| EP0042298A1 (en) | 1981-12-23 |
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