MY193623A - Method for producing a pharmaceutically stable composition presented as an aqueous solution - Google Patents
Method for producing a pharmaceutically stable composition presented as an aqueous solutionInfo
- Publication number
- MY193623A MY193623A MYPI2019001541A MYPI2019001541A MY193623A MY 193623 A MY193623 A MY 193623A MY PI2019001541 A MYPI2019001541 A MY PI2019001541A MY PI2019001541 A MYPI2019001541 A MY PI2019001541A MY 193623 A MY193623 A MY 193623A
- Authority
- MY
- Malaysia
- Prior art keywords
- producing
- aqueous solution
- composition presented
- tris
- minutes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to chemical and pharmaceutical industry and, in particular, to a method for producing a stabilized pharmaceutical composition presented as an aqueous solution that may be used to obtain an intravenous drug containing succinic acid, nicotinamide, inosine and riboflavin mononucleotide as the active ingredients and possessing cytoprotective properties. In accordance with the invention, the composition is supplemented by one or several of the pharmaceutically acceptable components as the stabilizing agent to be selected from the group including sodium hydroxide, tris(hydroxymethyl)aminomethane (TRIS), ethanolamine, diethanolamine, sodium carbonate, meglumine, up to a stable solution with pH from 6.0 to 8.0, the components? ratio,%wt, and the solution is subjected to additional thermal sterilization at 100?? with exposure time of 8 minutes to 116?? with exposure time of 2 minutes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2016138632A RU2629204C1 (en) | 2016-09-29 | 2016-09-29 | Method for obtaining of stabilized pharmaceutical composition as aqueous solution |
PCT/RU2017/000658 WO2018063028A1 (en) | 2016-09-29 | 2017-09-07 | Method for producing a stabilized pharmaceutical composition in the form of an aqueous solution |
Publications (1)
Publication Number | Publication Date |
---|---|
MY193623A true MY193623A (en) | 2022-10-20 |
Family
ID=59744837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI2019001541A MY193623A (en) | 2016-09-29 | 2017-09-07 | Method for producing a pharmaceutically stable composition presented as an aqueous solution |
Country Status (14)
Country | Link |
---|---|
CN (1) | CN110022858B (en) |
AR (1) | AR109775A1 (en) |
BR (1) | BR112019006167A2 (en) |
CL (1) | CL2019000810A1 (en) |
CO (1) | CO2019004133A2 (en) |
EA (1) | EA029693B1 (en) |
EC (1) | ECSP19030392A (en) |
MD (1) | MD4774C1 (en) |
MY (1) | MY193623A (en) |
PH (1) | PH12019500702A1 (en) |
RU (1) | RU2629204C1 (en) |
UA (1) | UA118387C2 (en) |
UY (1) | UY37426A (en) |
WO (1) | WO2018063028A1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2651047C1 (en) * | 2017-05-04 | 2018-04-18 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Drug composition of cytoprotective action and method for production thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2059417C1 (en) * | 1992-10-01 | 1996-05-10 | Данилевич Василий Николаевич | Method for sterilization of nutrient media |
KR20010033563A (en) * | 1997-12-25 | 2001-04-25 | 다카하시 데츠로 | Water-base liquid preparation |
EA001099B1 (en) * | 1999-06-10 | 2000-10-30 | Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" | Injecting medical preparation "citoflavin" possessing cito-pretecting effect |
JP2002161047A (en) * | 2000-11-28 | 2002-06-04 | Terumo Corp | Hemoglobin solution and hemoglobin-containing liposome |
RU2238108C1 (en) * | 2003-01-27 | 2004-10-20 | Нестерук Владимир Викторович | Method for sterilizing sodium chloride injection solution |
CN1679615A (en) * | 2005-02-04 | 2005-10-12 | 北京阜康仁生物制药科技有限公司 | Compound infantile energy mistura soluble vitamin preparation and use thereof |
CN101601647B (en) * | 2009-07-09 | 2010-09-15 | 周晓东 | Riboflavine sodium phosphate composition injection and preparation method thereof |
RU2536994C1 (en) * | 2013-05-17 | 2014-12-27 | Общество С Ограниченной Ответственностью "Нпо "Нефрон" | Concentrated acidic component, kit for producing it, concentrated solution of acidic component for producing hemodialysis solution and method for producing it |
WO2015113035A1 (en) * | 2014-01-27 | 2015-07-30 | Abbott Laboratories | Aseptic filtration process |
US20170224726A1 (en) * | 2014-02-18 | 2017-08-10 | Glenn Abrahmsohn | Compositions and methods for pain relief without numbness |
US10627407B2 (en) * | 2015-03-12 | 2020-04-21 | Mars, Incorporated | Ultra high resolution mass spectrometry and methods of using the same |
-
2016
- 2016-09-29 RU RU2016138632A patent/RU2629204C1/en active IP Right Revival
-
2017
- 2017-02-16 EA EA201700072A patent/EA029693B1/en unknown
- 2017-02-23 UA UAA201701703A patent/UA118387C2/en unknown
- 2017-09-07 WO PCT/RU2017/000658 patent/WO2018063028A1/en active Application Filing
- 2017-09-07 CN CN201780073686.9A patent/CN110022858B/en active Active
- 2017-09-07 MY MYPI2019001541A patent/MY193623A/en unknown
- 2017-09-07 MD MDA20190038A patent/MD4774C1/en not_active IP Right Cessation
- 2017-09-07 BR BR112019006167A patent/BR112019006167A2/en active Search and Examination
- 2017-09-29 UY UY0001037426A patent/UY37426A/en not_active Application Discontinuation
- 2017-09-29 AR ARP170102733A patent/AR109775A1/en unknown
-
2019
- 2019-03-27 CL CL2019000810A patent/CL2019000810A1/en unknown
- 2019-03-29 PH PH12019500702A patent/PH12019500702A1/en unknown
- 2019-04-26 CO CONC2019/0004133A patent/CO2019004133A2/en unknown
- 2019-04-29 EC ECSENADI201930392A patent/ECSP19030392A/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2018063028A1 (en) | 2018-04-05 |
MD4774B1 (en) | 2021-11-30 |
EA201700072A1 (en) | 2018-03-30 |
BR112019006167A2 (en) | 2019-06-18 |
RU2629204C1 (en) | 2017-08-25 |
ECSP19030392A (en) | 2019-08-30 |
CL2019000810A1 (en) | 2019-08-02 |
CO2019004133A2 (en) | 2019-09-30 |
UA118387C2 (en) | 2019-01-10 |
UY37426A (en) | 2018-04-30 |
CN110022858B (en) | 2021-12-14 |
MD20190038A2 (en) | 2019-10-31 |
CN110022858A (en) | 2019-07-16 |
MD4774C1 (en) | 2022-06-30 |
PH12019500702A1 (en) | 2019-11-25 |
EA029693B1 (en) | 2018-04-30 |
AR109775A1 (en) | 2019-01-23 |
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