MXPA06003978A - Constructos de acidos nucleicos. - Google Patents
Constructos de acidos nucleicos.Info
- Publication number
- MXPA06003978A MXPA06003978A MXPA06003978A MXPA06003978A MXPA06003978A MX PA06003978 A MXPA06003978 A MX PA06003978A MX PA06003978 A MXPA06003978 A MX PA06003978A MX PA06003978 A MXPA06003978 A MX PA06003978A MX PA06003978 A MXPA06003978 A MX PA06003978A
- Authority
- MX
- Mexico
- Prior art keywords
- sequence
- nucleic acid
- acid construct
- promoter
- antigen
- Prior art date
Links
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50993603P | 2003-10-10 | 2003-10-10 | |
| PCT/GB2004/004279 WO2005035771A2 (en) | 2003-10-10 | 2004-10-11 | Nucleic acid constructs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA06003978A true MXPA06003978A (es) | 2006-06-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA06003978A MXPA06003978A (es) | 2003-10-10 | 2004-10-11 | Constructos de acidos nucleicos. |
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| JP (1) | JP4814099B2 (https=) |
| KR (2) | KR101225395B1 (https=) |
| CN (1) | CN1890375B (https=) |
| AU (1) | AU2004279991B2 (https=) |
| BR (1) | BRPI0415204A (https=) |
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| PL (1) | PL1685251T3 (https=) |
| PT (1) | PT1685251E (https=) |
| SG (1) | SG147430A1 (https=) |
| SI (1) | SI1685251T1 (https=) |
| WO (1) | WO2005035771A2 (https=) |
| ZA (1) | ZA200603685B (https=) |
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| GB0507997D0 (en) * | 2005-02-01 | 2005-05-25 | Powderject Vaccines Inc | Nucleic acid constructs |
| JP2009511014A (ja) * | 2005-10-05 | 2009-03-19 | ベイヒル セラピューティクス インコーポレーティッド | 自己免疫疾患の処置のための組成物および方法 |
| US8466271B2 (en) | 2008-07-23 | 2013-06-18 | Boehringer Ingelheim Pharma Gmbh & Co, Kg | Regulatory elements |
| HUE042177T2 (hu) * | 2009-12-01 | 2019-06-28 | Translate Bio Inc | Szteroidszármazék mRNS szállítására humán genetikai betegségekben |
| WO2012019630A1 (en) | 2010-08-13 | 2012-02-16 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein |
| CN101993878B (zh) * | 2010-10-14 | 2012-04-18 | 南京农业大学 | 一种rRNA嵌合启动子及含有该嵌合启动子的表达载体 |
| WO2012075040A2 (en) | 2010-11-30 | 2012-06-07 | Shire Human Genetic Therapies, Inc. | mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES |
| PL3586861T3 (pl) | 2011-06-08 | 2022-05-23 | Translate Bio, Inc. | Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna |
| WO2013120500A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigen |
| WO2013120499A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen |
| WO2013120498A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded allergenic antigen or an autoimmune self-antigen |
| WO2013120497A1 (en) | 2012-02-15 | 2013-08-22 | Curevac Gmbh | Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein |
| WO2013143700A2 (en) | 2012-03-27 | 2013-10-03 | Curevac Gmbh | Artificial nucleic acid molecules comprising a 5'top utr |
| SG10201607962RA (en) * | 2012-03-27 | 2016-11-29 | Curevac Ag | Artificial nucleic acid molecules |
| RU2658490C2 (ru) | 2012-03-27 | 2018-06-21 | Кьюрвак Аг | Искусственные молекулы нуклеиновых кислот для улучшенной экспрессии белков или пептидов |
| EP3536787A1 (en) | 2012-06-08 | 2019-09-11 | Translate Bio, Inc. | Nuclease resistant polynucleotides and uses thereof |
| DK2711426T3 (en) | 2012-09-24 | 2015-07-13 | Lonza Biologics Plc | Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences |
| EP2938725B1 (en) | 2012-12-31 | 2017-08-23 | Boehringer Ingelheim International GmbH | Heterologous intron within an immunoglobulin domain |
| EP2938726B1 (en) | 2012-12-31 | 2017-09-27 | Boehringer Ingelheim International GmbH | Heterologous intron within a signal peptide |
| WO2014102104A1 (en) * | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Artificial introns |
| WO2014102101A1 (en) * | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Novel intron sequences |
| KR20210122917A (ko) | 2013-03-14 | 2021-10-12 | 샤이어 휴먼 지네틱 테라피즈 인크. | Cftr mrna 조성물 및 관련 방법 및 사용 |
| PL3467108T3 (pl) | 2013-03-14 | 2024-09-30 | Translate Bio, Inc. | Sposoby oczyszczania informacyjnego rna |
| ES2707966T3 (es) | 2013-10-22 | 2019-04-08 | Translate Bio Inc | Terapia de ARNm para la deficiencia en síntesis de argininosuccinato |
| EA034103B1 (ru) | 2013-10-22 | 2019-12-27 | Транслейт Био, Инк. | СПОСОБ ЛЕЧЕНИЯ ФЕНИЛКЕТОНУРИИ С ПРИМЕНЕНИЕМ мРНК |
| KR102399799B1 (ko) * | 2013-12-30 | 2022-05-18 | 큐어백 아게 | 인공 핵산 분자 |
| US11254951B2 (en) | 2014-12-30 | 2022-02-22 | Curevac Ag | Artificial nucleic acid molecules |
| CN103901209B (zh) * | 2014-02-18 | 2016-05-25 | 王明丽 | 一种重组蛋白ie1包被酶标反应板的制备方法及定量检测人血浆hcmv中和抗体试剂盒 |
| PT3134506T (pt) | 2014-04-25 | 2019-10-31 | Translate Bio Inc | Métodos de purificação de rna mensageiro |
| CN106459999B (zh) * | 2014-06-18 | 2024-10-11 | 新加坡科技研究局 | 用于高水平表达的新型启动子 |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EA201991747A1 (ru) | 2017-02-27 | 2020-06-04 | Транслейт Био, Инк. | НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR |
| MX2019013752A (es) | 2017-05-16 | 2020-07-20 | Translate Bio Inc | Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones. |
| WO2019060649A1 (en) * | 2017-09-22 | 2019-03-28 | Voyager Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR TREATING HUNTINGTON'S DISEASE |
| CA3108544A1 (en) | 2018-08-24 | 2020-02-27 | Translate Bio, Inc. | Methods for purification of messenger rna |
| MX2021005969A (es) | 2018-11-21 | 2021-09-14 | Translate Bio Inc | Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr nebulizado. |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| TWI810589B (zh) | 2020-06-21 | 2023-08-01 | 美商輝瑞股份有限公司 | 人巨細胞病毒糖蛋白Ｂ（ｇＢ）多肽 |
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| DE3431140A1 (de) * | 1984-08-24 | 1986-03-06 | Behringwerke Ag, 3550 Marburg | Enhancer fuer eukaryotische expressionssysteme |
| US5100792A (en) * | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| TW404844B (en) * | 1993-04-08 | 2000-09-11 | Oxford Biosciences Ltd | Needleless syringe |
| CA2158733C (en) * | 1994-01-21 | 2007-01-16 | Dennis E. Mccabe | Gas driven gene delivery instrument |
| ATE475668T1 (de) | 1994-01-27 | 2010-08-15 | Univ Massachusetts Medical | Immunisierung durch impfung von dns transkriptionseinheit |
| WO1996037221A1 (en) * | 1995-05-24 | 1996-11-28 | Hawaii Biotechnology Group, Inc. | Subunit vaccine against flavivirus infection |
| US6110707A (en) * | 1996-01-19 | 2000-08-29 | Board Of Regents, The University Of Texas System | Recombinant expression of proteins from secretory cell lines |
| GB9715064D0 (en) | 1997-07-17 | 1997-09-24 | Ppl Therapeutics Scotland Ltd | Protein expression |
| US20020106635A1 (en) | 1998-05-27 | 2002-08-08 | Bruce Freimark | Cytokine resistant cytomegalovirus promoter mutants and related products and methods |
| ATE319826T1 (de) * | 1998-10-19 | 2006-03-15 | Powderject Vaccines Inc | Minimale promotoren und ihre verwendung |
| WO2001058483A2 (en) | 2000-02-08 | 2001-08-16 | The University Of Virginia Patent Foundation | METHODS FOR THE PREVENTION AND TREATMENT OF INFECTIONS USING ANTI-C3b(i) ANTIBODIES |
| GB0027088D0 (en) | 2000-11-06 | 2000-12-20 | Glaxo Group Ltd | DNA expression vectors |
| US20030124523A1 (en) * | 2000-06-22 | 2003-07-03 | Asselbergs Fredericus Alphonsus Maria | Organic compounds |
| EP1373524B1 (en) * | 2000-10-13 | 2006-04-12 | Chiron Corporation | Cytomegalovirus intron a fragments |
| ATE442858T1 (de) | 2000-11-27 | 2009-10-15 | Powderject Vaccines Inc | Nukleinsäureadjuvantien |
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| JP2004535799A (ja) * | 2001-05-18 | 2004-12-02 | パウダージェクト ワクチンズ，インコーポレーテッド | ワクチン組成物 |
| GB0118367D0 (en) * | 2001-07-27 | 2001-09-19 | Glaxosmithkline Biolog Sa | Novel use |
| CN1889963A (zh) | 2003-10-10 | 2007-01-03 | 宝德杰克特疫苗有限公司 | 方法 |
| GB0507997D0 (en) | 2005-02-01 | 2005-05-25 | Powderject Vaccines Inc | Nucleic acid constructs |
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2004
- 2004-10-11 WO PCT/GB2004/004279 patent/WO2005035771A2/en not_active Ceased
- 2004-10-11 EP EP04768811.4A patent/EP1685251B1/en not_active Expired - Lifetime
- 2004-10-11 NZ NZ546554A patent/NZ546554A/en not_active IP Right Cessation
- 2004-10-11 MX MXPA06003978A patent/MXPA06003978A/es active IP Right Grant
- 2004-10-11 SG SG200807573-1A patent/SG147430A1/en unknown
- 2004-10-11 JP JP2006530599A patent/JP4814099B2/ja not_active Expired - Fee Related
- 2004-10-11 CN CN2004800367871A patent/CN1890375B/zh not_active Expired - Fee Related
- 2004-10-11 PT PT47688114T patent/PT1685251E/pt unknown
- 2004-10-11 PL PL04768811T patent/PL1685251T3/pl unknown
- 2004-10-11 US US10/575,087 patent/US8663657B2/en not_active Expired - Fee Related
- 2004-10-11 KR KR1020067009012A patent/KR101225395B1/ko not_active Expired - Fee Related
- 2004-10-11 DK DK04768811.4T patent/DK1685251T3/en active
- 2004-10-11 EA EA200600746A patent/EA010056B1/ru not_active IP Right Cessation
- 2004-10-11 KR KR1020117024399A patent/KR101234981B1/ko not_active Expired - Fee Related
- 2004-10-11 AU AU2004279991A patent/AU2004279991B2/en not_active Ceased
- 2004-10-11 ES ES04768811.4T patent/ES2457022T3/es not_active Expired - Lifetime
- 2004-10-11 BR BRPI0415204-2A patent/BRPI0415204A/pt active Search and Examination
- 2004-10-11 SI SI200432144T patent/SI1685251T1/sl unknown
- 2004-10-11 CA CA002542288A patent/CA2542288A1/en not_active Abandoned
-
2006
- 2006-04-06 IL IL174848A patent/IL174848A/en active IP Right Review Request
- 2006-05-09 ZA ZA200603685A patent/ZA200603685B/en unknown
- 2006-05-09 NO NO20062080A patent/NO20062080L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004279991B2 (en) | 2010-11-25 |
| CN1890375A (zh) | 2007-01-03 |
| ES2457022T3 (es) | 2014-04-24 |
| WO2005035771A2 (en) | 2005-04-21 |
| KR20060125742A (ko) | 2006-12-06 |
| JP4814099B2 (ja) | 2011-11-09 |
| IL174848A (en) | 2011-06-30 |
| WO2005035771A3 (en) | 2005-08-25 |
| KR101225395B1 (ko) | 2013-01-28 |
| JP2007509607A (ja) | 2007-04-19 |
| EP1685251B1 (en) | 2014-03-05 |
| ZA200603685B (en) | 2007-09-26 |
| NZ546554A (en) | 2009-04-30 |
| CN1890375B (zh) | 2011-12-07 |
| PL1685251T3 (pl) | 2014-07-31 |
| PT1685251E (pt) | 2014-04-15 |
| KR20110120364A (ko) | 2011-11-03 |
| SG147430A1 (en) | 2008-11-28 |
| AU2004279991A1 (en) | 2005-04-21 |
| EP1685251A2 (en) | 2006-08-02 |
| IL174848A0 (en) | 2006-08-20 |
| BRPI0415204A (pt) | 2006-12-05 |
| US8663657B2 (en) | 2014-03-04 |
| EA010056B1 (ru) | 2008-06-30 |
| CA2542288A1 (en) | 2005-04-21 |
| NO20062080L (no) | 2006-05-09 |
| EA200600746A1 (ru) | 2006-10-27 |
| US20080160048A1 (en) | 2008-07-03 |
| KR101234981B1 (ko) | 2013-02-21 |
| SI1685251T1 (sl) | 2014-05-30 |
| DK1685251T3 (en) | 2014-03-24 |
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