MXPA06000410A - Procedimiento para preparar profarmacos isomericamente puros de inhibidores de la bomba de protones. - Google Patents

Procedimiento para preparar profarmacos isomericamente puros de inhibidores de la bomba de protones.

Info

Publication number
MXPA06000410A
MXPA06000410A MXPA06000410A MXPA06000410A MXPA06000410A MX PA06000410 A MXPA06000410 A MX PA06000410A MX PA06000410 A MXPA06000410 A MX PA06000410A MX PA06000410 A MXPA06000410 A MX PA06000410A MX PA06000410 A MXPA06000410 A MX PA06000410A
Authority
MX
Mexico
Prior art keywords
proton pump
pump inhibitors
isomerically pure
prodrugs
pure prodrugs
Prior art date
Application number
MXPA06000410A
Other languages
English (en)
Inventor
Thomas C Malone
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MXPA06000410A publication Critical patent/MXPA06000410A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Ceramic Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen metodos de sintesis de profarmacos isomericamente puros de inhibidores de la bomba de protones. En una modalidad preferida se describen metodos para la sintesis de isomeros de los precursores omeprazol y pantoprazol.
MXPA06000410A 2003-07-15 2004-01-15 Procedimiento para preparar profarmacos isomericamente puros de inhibidores de la bomba de protones. MXPA06000410A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48734003P 2003-07-15 2003-07-15
PCT/US2004/001154 WO2005016917A1 (en) 2003-07-15 2004-01-15 Process for preparing isomerically pure prodrugs of proton pump inhibitors

Publications (1)

Publication Number Publication Date
MXPA06000410A true MXPA06000410A (es) 2006-03-17

Family

ID=34193068

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06000410A MXPA06000410A (es) 2003-07-15 2004-01-15 Procedimiento para preparar profarmacos isomericamente puros de inhibidores de la bomba de protones.

Country Status (16)

Country Link
US (1) US7294716B2 (es)
EP (1) EP1644352A1 (es)
JP (1) JP2007521314A (es)
KR (1) KR20060041224A (es)
CN (1) CN1823058A (es)
AR (1) AR042950A1 (es)
AU (1) AU2004264401A1 (es)
BR (1) BRPI0412590A (es)
CA (1) CA2532104A1 (es)
IL (1) IL172623A0 (es)
MX (1) MXPA06000410A (es)
NZ (1) NZ544173A (es)
PL (1) PL379542A1 (es)
TW (1) TW200502232A (es)
WO (1) WO2005016917A1 (es)
ZA (1) ZA200510221B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683177B2 (en) * 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
WO2005082338A2 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Prodrugs for the intravenous administration of proton pump inhibitors
WO2005115498A1 (ja) * 2004-05-28 2005-12-08 Kitakyushu Institute Of Bioinfomatics And Bioevolution Inc. 間欠的に注液、除水操作を繰り返す血液透析装置
WO2007073301A1 (en) * 2005-12-23 2007-06-28 Astrazeneca Ab Benzoimidazole derivatives as prodrugs of proton pump inhibitors
WO2007081871A1 (en) * 2006-01-10 2007-07-19 Allergan, Inc. Therapeutic salt compositions of sulfonyl ester prodrugs of proton pump inhibitors and methods for their preparation
EP2294064A4 (en) * 2008-07-07 2011-10-05 Hetero Research Foundation PROCESS FOR PURIFYING RABEPRAZOLE-SODIUM
US8927559B2 (en) 2010-10-11 2015-01-06 Merck Sharp & Dohme Corp. Quinazolinone-type compounds as CRTH2 antagonists
JP5952829B2 (ja) 2010-12-23 2016-07-13 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． Ｃｒｔｈ２受容体調節剤としてのキノキサリン類およびアザ−キノキサリン類
WO2012087872A1 (en) 2010-12-23 2012-06-28 Merck Sharp & Dohme Corp. Quinolines and aza-quinolines as crth2 receptor modulators
CN103232389A (zh) * 2013-05-08 2013-08-07 浙江新三和医药化工股份有限公司 2-氯甲基-4-甲氧基-3,5-二甲基吡啶盐酸盐的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
JP4346243B2 (ja) * 1998-08-10 2009-10-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア プロトン・ポンプ・インヒビターのプロドラッグ
US6348032B1 (en) * 1998-11-23 2002-02-19 Cell Pathways, Inc. Method of inhibiting neoplastic cells with benzimidazole derivatives
US6599167B2 (en) * 2000-09-27 2003-07-29 Glenn Waltz Game call holder and amplifying device
WO2004009583A2 (en) * 2002-07-19 2004-01-29 Garst Michael E Benzimidazole derivatives and their use as prodrugs of proton pump inhibitor

Also Published As

Publication number Publication date
US7294716B2 (en) 2007-11-13
ZA200510221B (en) 2006-12-27
EP1644352A1 (en) 2006-04-12
IL172623A0 (en) 2006-04-10
NZ544173A (en) 2009-04-30
CN1823058A (zh) 2006-08-23
AU2004264401A1 (en) 2005-02-24
KR20060041224A (ko) 2006-05-11
AR042950A1 (es) 2005-07-06
WO2005016917A1 (en) 2005-02-24
PL379542A1 (pl) 2006-10-02
CA2532104A1 (en) 2005-02-24
JP2007521314A (ja) 2007-08-02
BRPI0412590A (pt) 2006-09-19
US20050038076A1 (en) 2005-02-17
TW200502232A (en) 2005-01-16

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