MXPA05008913A - Formulacion oftalmica estable que contiene antibiotico y corticoesteroide. - Google Patents
Formulacion oftalmica estable que contiene antibiotico y corticoesteroide.Info
- Publication number
- MXPA05008913A MXPA05008913A MXPA05008913A MXPA05008913A MXPA05008913A MX PA05008913 A MXPA05008913 A MX PA05008913A MX PA05008913 A MXPA05008913 A MX PA05008913A MX PA05008913 A MXPA05008913 A MX PA05008913A MX PA05008913 A MXPA05008913 A MX PA05008913A
- Authority
- MX
- Mexico
- Prior art keywords
- corticosteroid
- antibiotic
- formulation containing
- ophthalmic formulation
- stable ophthalmic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invencion presente una composicion oftalmica estable y transparente constituida por: (a) una quinolona o un aminoglicosido, (b) un corticosteroide, (c) una ciclodextrina y (d) otros excipientes farmaceuticamente aceptables en un vehiculo liquido.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN212MU2003 | 2003-02-21 | ||
PCT/IN2004/000048 WO2004087043A2 (en) | 2003-02-21 | 2004-02-23 | Stable ophthalmic formulation containing an antibiotic and a corticosteroid |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05008913A true MXPA05008913A (es) | 2005-10-05 |
Family
ID=33104995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05008913A MXPA05008913A (es) | 2003-02-21 | 2004-02-23 | Formulacion oftalmica estable que contiene antibiotico y corticoesteroide. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20070148192A1 (es) |
EP (1) | EP1596823A2 (es) |
JP (1) | JP2006518769A (es) |
KR (1) | KR20050105477A (es) |
BR (1) | BRPI0407583A (es) |
CA (1) | CA2516429A1 (es) |
MX (1) | MXPA05008913A (es) |
WO (1) | WO2004087043A2 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310590A (en) * | 1993-02-04 | 1994-05-10 | Minnesota Mining And Manufacturing Company | Stitchbonded articles |
US20070224278A1 (en) | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
US20050101582A1 (en) | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
US20070020299A1 (en) | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid |
US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
AU2005209201B2 (en) | 2004-01-20 | 2010-06-03 | Allergan, Inc. | Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid |
US8119154B2 (en) | 2004-04-30 | 2012-02-21 | Allergan, Inc. | Sustained release intraocular implants and related methods |
WO2006043965A1 (en) * | 2004-10-14 | 2006-04-27 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
CA2615360A1 (en) * | 2005-07-15 | 2007-01-25 | Chakshu Research Inc. | Formulation and method for administration of ophthalmologically active agents |
WO2007099431A2 (en) * | 2006-02-28 | 2007-09-07 | Wockhardt Ltd | An aqueous liquid pharmaceutical compositions of gatifloxacin |
DE102006010643A1 (de) * | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
US7767217B2 (en) * | 2006-03-14 | 2010-08-03 | Foresight Biotherapeutics | Ophthalmic compositions comprising povidone-iodine |
AU2016253668B2 (en) * | 2006-03-14 | 2018-12-06 | Cls Pharmaceuticals, Inc. | Ophthalmic compositions comprising povidone-iodine |
WO2008002117A1 (es) * | 2006-06-27 | 2008-01-03 | Jimenez Bayardo, Arturo | Solución oftálmica de ciprofloxacina y dexametasona |
US9039761B2 (en) | 2006-08-04 | 2015-05-26 | Allergan, Inc. | Ocular implant delivery assemblies with distal caps |
JP2010531898A (ja) * | 2007-06-28 | 2010-09-30 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | 鼻および眼へのコルチコステロイド水溶液送達 |
ES2493641T3 (es) * | 2007-06-28 | 2014-09-12 | Cydex Pharmaceuticals, Inc. | Administración nasal de soluciones acuosas de corticosteroides |
BRPI0908229A8 (pt) * | 2008-02-25 | 2017-10-10 | Eyegate Pharma S A S | Uso de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste, kit e dispositivo para dispensar iontoforeticamente um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente para tratar um distúrbio ocular mediado por inflamação no referido paciente, e, formulação apropriada para dispensação iontoforética ocular de um corticosteróide, derivado de corticosteróide, pró-fármaco ou sal deste no olho de um paciente |
US20110117189A1 (en) * | 2008-07-08 | 2011-05-19 | S.I.F.I. Societa' Industria Farmaceutica Italiana S.P.A. | Ophthalmic compositions for treating pathologies of the posterior segment of the eye |
EP2502616A1 (fr) * | 2011-03-21 | 2012-09-26 | Matthew Krayenbuhl | Composition pharmaceutique nasale |
KR101304341B1 (ko) * | 2011-09-19 | 2013-09-11 | 한미약품 주식회사 | 코르티코스테로이드, 항히스타민제 및 β-사이클로덱스트린을 포함하는, 안정성이 개선된 약학 조성물 |
US9504691B2 (en) * | 2012-12-06 | 2016-11-29 | Alcon Research, Ltd. | Finafloxacin suspension compositions |
US20160279055A1 (en) | 2013-07-22 | 2016-09-29 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof |
US20150164882A1 (en) | 2013-07-22 | 2015-06-18 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions for intraocular administration and methods for fabricating thereof |
EP3452033A4 (en) * | 2016-05-06 | 2020-02-12 | Harrow IP, LLC | PHARMACEUTICAL OPHTHALMIC COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF |
BR112019011067A2 (pt) * | 2016-11-29 | 2019-12-17 | Oculis SA | preparação de complexos sólidos de ciclodextrina para administração de ingredientes farmacêuticos oftalmológicos ativos |
EP3906263A4 (en) | 2019-01-03 | 2022-08-31 | Underdog Pharmaceuticals, Inc. | CYCLODEXTRIN DIMERS, THEIR COMPOSITIONS AND USES |
US20230233572A1 (en) * | 2020-06-11 | 2023-07-27 | Sentiss Pharma Private Limited | Ophthalmic compositions comprising a combination of fluoroquinolone antibacterial agent and an anti-inflammatory agent |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3704907A1 (de) * | 1987-02-17 | 1988-08-25 | Bayer Ag | Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden |
AU4201189A (en) * | 1988-08-26 | 1990-03-23 | Alcon Laboratories, Inc. | Combination of quinolone antibiotics and steroids for topical ophthalmic use |
US5422116A (en) * | 1994-02-18 | 1995-06-06 | Ciba-Geigy Corporation | Liquid ophthalmic sustained release delivery system |
DK1214056T3 (da) * | 1999-09-24 | 2004-02-09 | Alcon Inc | Topiske suspensionsformuleringer indeholdende ciprofloxacin og dexamethason |
US20010049366A1 (en) * | 2000-02-09 | 2001-12-06 | Alcon Universal Ltd. | Topical solution formulations containing an antibiotic and a corticosteroid |
CA2428189A1 (en) * | 2000-11-15 | 2002-05-23 | Mainde Chandrashekhar | Pharmaceutival preparations comprising corticosteroids and antiinfective agents |
-
2004
- 2004-02-23 KR KR1020057015370A patent/KR20050105477A/ko not_active Application Discontinuation
- 2004-02-23 EP EP04745101A patent/EP1596823A2/en not_active Withdrawn
- 2004-02-23 WO PCT/IN2004/000048 patent/WO2004087043A2/en active Application Filing
- 2004-02-23 MX MXPA05008913A patent/MXPA05008913A/es unknown
- 2004-02-23 BR BRPI0407583-8A patent/BRPI0407583A/pt not_active IP Right Cessation
- 2004-02-23 CA CA002516429A patent/CA2516429A1/en not_active Abandoned
- 2004-02-23 JP JP2006507625A patent/JP2006518769A/ja active Pending
- 2004-02-23 US US10/546,417 patent/US20070148192A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20050105477A (ko) | 2005-11-04 |
EP1596823A2 (en) | 2005-11-23 |
JP2006518769A (ja) | 2006-08-17 |
WO2004087043B1 (en) | 2005-01-27 |
WO2004087043A3 (en) | 2004-12-16 |
CA2516429A1 (en) | 2004-10-14 |
WO2004087043A2 (en) | 2004-10-14 |
US20070148192A1 (en) | 2007-06-28 |
BRPI0407583A (pt) | 2006-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA05008913A (es) | Formulacion oftalmica estable que contiene antibiotico y corticoesteroide. | |
WO2004093795A3 (en) | Compositions for delivery of drug combinations | |
TW200621238A (en) | Pharmaceutical formulation | |
WO2004091446A3 (en) | Medical device delivery systems | |
WO2005025499A3 (en) | Hydrophobic drug compositions containing reconstitution enhancer | |
WO2006105172A3 (en) | Peg-polyacetal and peg-polyacetal-poe graft copolymers and pharmaceutical compositions | |
MXPA03007591A (es) | Composiciones y metodos para mejorar el suministro de farmacos a traves de y a tejidos epiteliales. | |
WO2007019554A3 (en) | Polysaccharides for delivery of active agents | |
AU2001234504A1 (en) | Methods, systems, and presentations for delivery over the internet | |
WO2004064769A3 (en) | Methods for making and using topical delivery agents | |
EA200901393A1 (ru) | Фармацевтическая композиция, содержащая гестагены и/или эстрогены и 5 метил-(6s)-тетрагидрофолат | |
EP1589947B8 (en) | Pharmaceutical formulation with an insoluble active agent for pulmonary administration | |
MX2007002189A (es) | Sales de dicetopiperazina, sales de dicetomorfolina o sales de dicetodioxano para suministro de farmacos. | |
WO2004058837A3 (de) | Ampholytisches copolymer und dessen verwendung | |
AU2001261752A1 (en) | Compositions and methods for treating otic, ophthalmic and nasal infections | |
WO2005009381A3 (en) | Immediate-release formulation of acid-labile pharmaceutical compositions | |
EP2431385A3 (en) | Combination therapy with chlorotoxin | |
AU2001269478A1 (en) | Hyaluronic acid oligosaccharide fractions and drugs containing the same | |
MX2010005013A (es) | Composiciones intranasales. | |
WO2003082926A3 (en) | Antimicrobial polymer conjugates | |
AU2002361042A1 (en) | Cosmetic agent containing at least one copolymer having n-vinyllactam units | |
AU2003253506A1 (en) | Pharmaceutical composition comprising estetrol derivatives for use in cancer therapy | |
AU2002317298A1 (en) | Formulation comprising fulvestrant | |
AU2001259303A1 (en) | Glycopeptide carboxy-saccharide derivatives | |
WO2008044782A3 (en) | Combination drug |