MXPA05008810A - Procedimientos para preparar derivados biciclicos sustituidos. - Google Patents

Procedimientos para preparar derivados biciclicos sustituidos.

Info

Publication number
MXPA05008810A
MXPA05008810A MXPA05008810A MXPA05008810A MXPA05008810A MX PA05008810 A MXPA05008810 A MX PA05008810A MX PA05008810 A MXPA05008810 A MX PA05008810A MX PA05008810 A MXPA05008810 A MX PA05008810A MX PA05008810 A MXPA05008810 A MX PA05008810A
Authority
MX
Mexico
Prior art keywords
processes
intermediates
preparation
well
pyridinyloxy
Prior art date
Application number
MXPA05008810A
Other languages
English (en)
Inventor
Girard Vetelino Michael
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MXPA05008810A publication Critical patent/MXPA05008810A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
    • C07C271/66—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)

Abstract

La invencion se refiere a procedimientos para preparar compuestos de formula 1 (ver formula 1) y a sus sales, profarmacos y disolventes farmaceuticamente aceptables, en la que R1, R3, R4, R6, R11, R13, R14, R15, R16, R17, k, l y m son como se han definido en la presente memoria; los compuestos de formula 1 son productos intermedios utiles para preparar compuestos que se pueden usar en el tratamiento del crecimiento celular anormal en mamiferos, administrando composiciones farmaceuticas.
MXPA05008810A 2003-04-09 2004-03-29 Procedimientos para preparar derivados biciclicos sustituidos. MXPA05008810A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46163203P 2003-04-09 2003-04-09
US51686003P 2003-11-03 2003-11-03
PCT/IB2004/001069 WO2004089934A1 (en) 2003-04-09 2004-03-29 Processes for the preparation of n-((((pyridinyloxy) -phenylamino) quinazolinyl)- allyl) acetamide derivatives and related compounds as well as intermediates of such processes and processes for the preparation of such intermediates

Publications (1)

Publication Number Publication Date
MXPA05008810A true MXPA05008810A (es) 2005-10-18

Family

ID=33162255

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008810A MXPA05008810A (es) 2003-04-09 2004-03-29 Procedimientos para preparar derivados biciclicos sustituidos.

Country Status (14)

Country Link
US (1) US20050026940A1 (es)
EP (1) EP1615910A1 (es)
JP (1) JP2006525305A (es)
KR (1) KR20050118726A (es)
AR (1) AR044213A1 (es)
AU (1) AU2004228460A1 (es)
BR (1) BRPI0409233A (es)
CA (1) CA2521348A1 (es)
CL (1) CL2004000744A1 (es)
MX (1) MXPA05008810A (es)
RS (1) RS20050652A (es)
RU (1) RU2005125607A (es)
TW (1) TW200426141A (es)
WO (1) WO2004089934A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1972688B (zh) * 2004-05-06 2012-06-27 沃尼尔·朗伯有限责任公司 4-苯胺基-喹唑啉-6-基-酰胺类化合物
CA2610491A1 (en) * 2005-06-03 2006-12-07 Pfizer Products Inc. Bicyclic derivatives for the treatment of abnormal cell growth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225318B1 (en) * 1996-10-17 2001-05-01 Pfizer Inc 4-aminoquinazolone derivatives
NZ522568A (en) * 2000-06-22 2004-12-24 Pfizer Prod Inc Substituted bicyclic derivatives for the treatment of abnormal cell growth
JP4220388B2 (ja) * 2001-11-30 2009-02-04 ファイザー・プロダクツ・インク 異常な細胞増殖を処置するための置換された二環式誘導体の製造方法

Also Published As

Publication number Publication date
TW200426141A (en) 2004-12-01
RU2005125607A (ru) 2006-03-27
CA2521348A1 (en) 2004-10-21
WO2004089934A1 (en) 2004-10-21
KR20050118726A (ko) 2005-12-19
JP2006525305A (ja) 2006-11-09
AU2004228460A1 (en) 2004-10-21
RS20050652A (en) 2007-11-15
EP1615910A1 (en) 2006-01-18
BRPI0409233A (pt) 2006-03-28
US20050026940A1 (en) 2005-02-03
AR044213A1 (es) 2005-09-07
CL2004000744A1 (es) 2005-02-11

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