MXPA05008652A - Uso del enantiomero (1s,2r) de milnacipran para la preparacion de un medicamento. - Google Patents

Uso del enantiomero (1s,2r) de milnacipran para la preparacion de un medicamento.

Info

Publication number
MXPA05008652A
MXPA05008652A MXPA05008652A MXPA05008652A MXPA05008652A MX PA05008652 A MXPA05008652 A MX PA05008652A MX PA05008652 A MXPA05008652 A MX PA05008652A MX PA05008652 A MXPA05008652 A MX PA05008652A MX PA05008652 A MXPA05008652 A MX PA05008652A
Authority
MX
Mexico
Prior art keywords
enantiomer
milnacipran
medicament
preparation
recapture
Prior art date
Application number
MXPA05008652A
Other languages
English (en)
Inventor
Richard Grosse
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0301849A external-priority patent/FR2851163B1/fr
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of MXPA05008652A publication Critical patent/MXPA05008652A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Addiction (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un metodo para tratar o prevenir un trastorno o una condicion mediante la doble inhibicion de la retoma de serotonina (5-HT) y noradrenalina (NA) en un sujeto que necesita de la misma, a la vez que se limitan los riesgos de alteraciones cardiovasculares y/o toxicidad de organo y/o de tejido, que comprende los pasos de administrar a dicho sujeto una mezcla de enantiomeros del milnacipran enriquecida en el (1S,2R) enantiomero del milnacipran y/o de al menos uno de sus metabolitos, asi como sus sales farmaceuticamente aceptables.
MXPA05008652A 2003-02-14 2004-02-16 Uso del enantiomero (1s,2r) de milnacipran para la preparacion de un medicamento. MXPA05008652A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0301849A FR2851163B1 (fr) 2003-02-14 2003-02-14 Utilisation de l'enantiomere dextrogyre du milnacipran pour la preparation d'un medicament
US10/453,574 US7005452B2 (en) 2003-02-14 2003-06-03 Use of the dextrogyral enantiomer of milnacipran for the preparation of a drug
PCT/FR2004/000347 WO2004075886A1 (fr) 2003-02-14 2004-02-16 Utilisation de l’enantiomere (1s, 2r) du milnacipran pour la preparation d’un medicament

Publications (1)

Publication Number Publication Date
MXPA05008652A true MXPA05008652A (es) 2005-10-18

Family

ID=32929266

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05008652A MXPA05008652A (es) 2003-02-14 2004-02-16 Uso del enantiomero (1s,2r) de milnacipran para la preparacion de un medicamento.

Country Status (20)

Country Link
US (2) US7074833B2 (es)
EP (2) EP1601349B1 (es)
KR (1) KR101185322B1 (es)
AT (1) ATE401872T1 (es)
AU (1) AU2004216452B2 (es)
BR (1) BRPI0407256A (es)
CA (1) CA2514948C (es)
DE (1) DE602004015257D1 (es)
DK (1) DK1601349T3 (es)
ES (1) ES2310715T3 (es)
HK (1) HK1079117A1 (es)
MA (1) MA27655A1 (es)
MX (1) MXPA05008652A (es)
NO (1) NO333987B1 (es)
NZ (1) NZ541733A (es)
PL (1) PL219671B1 (es)
PT (1) PT1601349E (es)
RU (1) RU2317817C2 (es)
SI (1) SI1601349T1 (es)
WO (1) WO2004075886A1 (es)

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Also Published As

Publication number Publication date
EP1908461B9 (fr) 2011-08-31
EP1908461A1 (fr) 2008-04-09
US7074833B2 (en) 2006-07-11
PT1601349E (pt) 2008-10-27
BRPI0407256A (pt) 2006-01-31
SI1601349T1 (sl) 2008-10-31
DK1601349T3 (da) 2008-10-27
RU2317817C2 (ru) 2008-02-27
KR20050096190A (ko) 2005-10-05
ES2310715T3 (es) 2009-01-16
PL219671B1 (pl) 2015-06-30
CA2514948A1 (fr) 2004-09-10
ATE401872T1 (de) 2008-08-15
AU2004216452B2 (en) 2008-10-16
MA27655A1 (fr) 2005-12-01
WO2004075886A1 (fr) 2004-09-10
NO20054228L (no) 2005-09-12
HK1079117A1 (en) 2006-03-31
EP1908461B1 (fr) 2011-03-16
US20040259953A1 (en) 2004-12-23
AU2004216452A1 (en) 2004-09-10
CA2514948C (fr) 2013-04-02
KR101185322B1 (ko) 2012-09-21
NO333987B1 (no) 2013-11-04
PL378057A1 (pl) 2006-02-20
US20060014837A1 (en) 2006-01-19
RU2005128548A (ru) 2006-01-20
EP1601349B1 (fr) 2008-07-23
DE602004015257D1 (de) 2008-09-04
EP1601349A1 (fr) 2005-12-07
NZ541733A (en) 2009-03-31

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