MXPA04011508A - Produccion de materiales cristalinos usando ultrasonido de alta intensidad. - Google Patents

Produccion de materiales cristalinos usando ultrasonido de alta intensidad.

Info

Publication number
MXPA04011508A
MXPA04011508A MXPA04011508A MXPA04011508A MXPA04011508A MX PA04011508 A MXPA04011508 A MX PA04011508A MX PA04011508 A MXPA04011508 A MX PA04011508A MX PA04011508 A MXPA04011508 A MX PA04011508A MX PA04011508 A MXPA04011508 A MX PA04011508A
Authority
MX
Mexico
Prior art keywords
ultrasound
solution
high intensity
production
vessel
Prior art date
Application number
MXPA04011508A
Other languages
English (en)
Inventor
Patrick Perkins John
Original Assignee
Accentus Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0212626.6A external-priority patent/GB0212626D0/en
Priority claimed from GB0302555A external-priority patent/GB0302555D0/en
Application filed by Accentus Plc filed Critical Accentus Plc
Publication of MXPA04011508A publication Critical patent/MXPA04011508A/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0004—Crystallisation cooling by heat exchange
    • B01D9/0013—Crystallisation cooling by heat exchange by indirect heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0036—Crystallisation on to a bed of product crystals; Seeding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0063—Control or regulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0081—Use of vibrations, e.g. ultrasound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00—Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10—Apparatus
    • Y10T117/1024—Apparatus for crystallization from liquid or supercritical state
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T117/00—Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor
    • Y10T117/10—Apparatus
    • Y10T117/1024—Apparatus for crystallization from liquid or supercritical state
    • Y10T117/1028—Crucibleless apparatus having means providing movement of discrete droplets or solid particles to thin-film precursor [e.g., Verneuil method]

Abstract

Puede hacerse un material cristalino suficientemente puro para su uso en farmaceutica, formando una solucion saturada del material, cambiando la temperatura de la solucion de modo que se sobresature, y sometiendo ala solucion a irradiacion por ultrasonido de alta intensidad, barriendo la frecuencia del ultrasonido a lo largo de un rango de frecuencias. Por ejemplo el ultrasonido puede ser variado entre 19.5 y 20.5 kHz, y esta variacion puede ser sinusoidal. Preferiblemente, el ultrasonido se proporciona solo brevemente, digamos durante menos de 5 s, antes de permitir que la solucion se enfrie gradualmente sin irradiacion posterior. El ultrasonido puede aplicarse usando un recipiente con un arreglo de transductores ultrasonicos unidos a un pared, de modo que cada transductor radie no mas de 3 W/cm2, siendo la disipacion de la potencia dentro del recipiente de entre 25 y 150 W/litro. Este metodo puede reducir el ancho de la zona metaestable hasta menos de 10 K. Es aplicable en particular al aspartame.
MXPA04011508A 2002-05-31 2003-05-13 Produccion de materiales cristalinos usando ultrasonido de alta intensidad. MXPA04011508A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0212626.6A GB0212626D0 (en) 2002-05-31 2002-05-31 Production of crystalline ingredients
GB0302555A GB0302555D0 (en) 2003-02-05 2003-02-05 Production of Crystalline materials
PCT/GB2003/002017 WO2003101578A1 (en) 2002-05-31 2003-05-13 Production of crystalline materials by using high intensity ultrasound

Publications (1)

Publication Number Publication Date
MXPA04011508A true MXPA04011508A (es) 2005-08-15

Family

ID=29713390

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04011508A MXPA04011508A (es) 2002-05-31 2003-05-13 Produccion de materiales cristalinos usando ultrasonido de alta intensidad.

Country Status (18)

Country Link
US (1) US7357835B2 (es)
EP (1) EP1509301B1 (es)
JP (1) JP4329936B2 (es)
CN (1) CN100342939C (es)
AT (1) ATE350121T1 (es)
AU (1) AU2003230006B2 (es)
BR (1) BR0311332A (es)
CA (1) CA2485941C (es)
DE (1) DE60310923T2 (es)
DK (1) DK1509301T3 (es)
ES (1) ES2279109T3 (es)
IL (1) IL165135A (es)
MX (1) MXPA04011508A (es)
NO (1) NO20045574L (es)
NZ (1) NZ536716A (es)
OA (1) OA12826A (es)
PT (1) PT1509301E (es)
WO (1) WO2003101578A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244307B2 (en) * 2002-05-31 2007-07-17 Accentus Plc Production of crystalline materials by using high intensity ultrasound
GB0405108D0 (en) * 2004-03-06 2004-04-07 Accentus Plc Removal of sodium oxalate from a bayer liquor
GB0413511D0 (en) * 2004-06-17 2004-07-21 Accentus Plc Precipitation of gibbsite from a bayer liquor
GB0415237D0 (en) * 2004-07-07 2004-08-11 Accentus Plc Formation of sugar coatings
GB0415227D0 (en) * 2004-07-07 2004-08-11 Accentus Plc Precipitation of silica in a Bayer process
GB0503193D0 (en) * 2005-02-16 2005-03-23 Accentus Plc Ultrasonic treatment plant
US7597148B2 (en) * 2005-05-13 2009-10-06 Baker Hughes Incorporated Formation and control of gas hydrates
EP1782797A1 (en) * 2005-11-02 2007-05-09 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmaceutical compounds.
GB0524823D0 (en) * 2005-12-06 2006-01-11 Accentus Plc Removal of contaminants from a bayer liquor
GB0821419D0 (en) * 2008-11-24 2008-12-31 Bio Sep Ltd Processing of biomass
NZ597065A (en) * 2009-05-14 2014-08-29 Cavitus Pty Ltd Density modification
US7999135B2 (en) 2009-07-21 2011-08-16 Ge Healthcare As Crystallization of iodixanol using ultrasound
EP2399658A1 (en) 2010-06-24 2011-12-28 Biosyn Arzneimittel GmbH Method for producing pharmacologically pure crystals
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
US20140031557A1 (en) * 2011-04-18 2014-01-30 Hefeibeinie Medical Technology Company, Ltd. Method for purification of calcium channel blockers of dihydorpyridine type and preparation of nanoparticles thereof
US20160136598A1 (en) 2013-07-03 2016-05-19 Pusonics S.L. Ultrasonic system for mixing multiphase media and liquids, and associated method
US10604730B2 (en) * 2015-10-16 2020-03-31 Terressentia Corporation Alcoholic beverage maturing device
CN107008028B (zh) * 2017-05-22 2023-09-08 天津晶润锐拓科技发展有限公司 一种通过超声波控制结晶成核过程的结晶器
WO2019103667A1 (en) * 2017-11-22 2019-05-31 Aak Ab (Publ) Process for dry fractionation of a palm oil olein
CN107963929A (zh) * 2017-12-05 2018-04-27 上海永通化工有限公司 一种植物营养元素结晶体及其制备方法
CN110354528B (zh) * 2019-08-21 2021-11-19 贺剑 溶液结晶系统及促进溶液结晶的方法
EP3925932A1 (en) 2020-06-17 2021-12-22 Biosyn Arzneimittel GmbH Contained production of pharmaceutically pure crystals
CN113521791A (zh) * 2021-06-23 2021-10-22 福建江夏学院 一种光电半导体薄膜的超声波振荡制备装置

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1347350A (en) * 1918-02-26 1920-07-20 Gen Electric Crystal production
US2876083A (en) * 1953-06-29 1959-03-03 Prietl Franz Process of producing crystals from particles of crystallizable substance distributedin a liquid
US3892539A (en) * 1969-09-26 1975-07-01 Merck & Co Inc Process for production of crystals in fluidized bed crystallizers
US4990216A (en) * 1987-10-27 1991-02-05 Fujitsu Limited Process and apparatus for preparation of single crystal of biopolymer
US5362455A (en) 1990-05-03 1994-11-08 Praxair Technology, Inc. Draft tube, direct contact cryogenic crystallizer
GB2276567B (en) 1993-04-03 1996-11-27 Atomic Energy Authority Uk Processing vessel
DE4431872C1 (de) 1994-09-07 1996-01-11 Santrade Ltd Anwendung von Ultraschall bei der Verfestigung von Schmelzen oder übersättigten Lösungen auf Förderbändern oder Aufnahmetrommeln
WO2000033366A1 (de) 1998-11-30 2000-06-08 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur herstellung von multikristallinem halbleitermaterial
GB9827360D0 (en) * 1998-12-12 1999-02-03 Aea Technology Plc Process and apparatus for irradiating fluids
FI122018B (fi) * 2000-01-31 2011-07-29 Danisco Menetelmä betaiinin kiteyttämiseksi
US6630185B2 (en) 2000-07-18 2003-10-07 Lipton, Division Of Conopco, Inc. Crystallization process using ultrasound
JP5008215B2 (ja) * 2000-09-29 2012-08-22 三菱瓦斯化学株式会社 晶析方法および装置
TWI285552B (en) * 2000-11-22 2007-08-21 Otsuka Pharma Co Ltd O/W-emulsion composition and method of preparation threof
BR0208886A (pt) * 2001-04-13 2004-06-29 Otsuka Pharma Co Ltd Promotor para absorção de sacarìdeo
PL364626A1 (en) * 2001-05-05 2004-12-13 Accentus Plc Formation of small crystals
DE10123073A1 (de) 2001-05-11 2003-03-27 Fraunhofer Ges Forschung Verfahren zur Herstellung von Kristallen aus in einem Lösungsmittel gelösten Feststoffen
WO2003057275A2 (en) * 2001-12-28 2003-07-17 Ekos Corporation Multi-resonant ultrasonic catheter
CA2472690A1 (en) * 2002-01-07 2003-07-17 Abbott Gmbh & Co. Kg Crystallization of amino acids using ultrasonic agitation
US7063741B2 (en) * 2002-03-27 2006-06-20 General Electric Company High pressure high temperature growth of crystalline group III metal nitrides

Also Published As

Publication number Publication date
IL165135A (en) 2008-11-03
IL165135A0 (en) 2005-12-18
AU2003230006B2 (en) 2008-06-19
AU2003230006A1 (en) 2003-12-19
ATE350121T1 (de) 2007-01-15
JP4329936B2 (ja) 2009-09-09
WO2003101578A1 (en) 2003-12-11
EP1509301A1 (en) 2005-03-02
ES2279109T3 (es) 2007-08-16
CN100342939C (zh) 2007-10-17
NZ536716A (en) 2006-08-31
DE60310923T2 (de) 2007-07-05
CA2485941C (en) 2011-02-01
EP1509301B1 (en) 2007-01-03
CN1655857A (zh) 2005-08-17
OA12826A (en) 2006-07-11
NO20045574L (no) 2004-12-21
US7357835B2 (en) 2008-04-15
CA2485941A1 (en) 2003-12-11
DK1509301T3 (da) 2007-03-19
DE60310923D1 (de) 2007-02-15
BR0311332A (pt) 2005-03-15
JP2005527368A (ja) 2005-09-15
PT1509301E (pt) 2007-01-31
US20050188913A1 (en) 2005-09-01

Similar Documents

Publication Publication Date Title
MXPA04011508A (es) Produccion de materiales cristalinos usando ultrasonido de alta intensidad.
ATE342111T1 (de) Herstellung von kristallmaterialien mit hochleistungsultraschall
DE3881402D1 (en) Shock wave or ultrasonic treatment
TW200502630A (en) Surface radiation conversion element, liquid crystal display device, and method of producing a surface radiation conversion element
IL144638A (en) High power ultrasound reactor for the production of nano-powder materials
DE59807772D1 (de) Vorrichtung zum herstellen von dispersen stoffgemischen mittels ultraschall und verwendung einer derartigen vorrichtung
SE8505310L (sv) Vagenergigenerator
Leighton Transient excitation of insonated bubbles
GB0217768D0 (en) Method and apparatus for forming a head on a beverage
JP2005527367A5 (es)
GB9827360D0 (en) Process and apparatus for irradiating fluids
CN101817571A (zh) 变频式超声波除藻仪
Lebedev et al. Ultrasonic oscillating system for radiators of gas media
Wang et al. The cavitation valley phenomenon of rectangular wave modulation ultrasound
CN1478561A (zh) 一种特超声治疗仪
Barone Aspects of the concentration of ultrasonic energy
NO20011899D0 (no) Fremgangsmåte for å oppnå fast overflate på pölsekjött med ultralydbehandling
JP3795601B2 (ja) 微弱超音波を用いた湖沼の汚染物質分解装置
SU1747186A1 (ru) Устройство дл ультразвуковой обработки
CN203737231U (zh) 一种近声场超声波反应器
Carnell et al. The generation of negative pressure waves for cavitation studies
JPS55165166A (en) Atomizing apparatus of liquid by ultrasonic wave
JPH0614977A (ja) 超音波殺菌方法及び装置
Brazhnikov et al. The field of an acoustic transducer in the region of detection of an ultrasonic wave beyond the near zone is considered as applied to nondestructive check of the surface density of foil-film materials by the method of their irradiation with an ultrasonic wave through air. The results obtained refine the existing concept of the pressure
CN109201441A (zh) 一种基于椭球型壳体的便携式多用超声换能器

Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights