MXPA04001201A - Derivados tetraciclicos de indol como ligandos del receptor de 5-ht. - Google Patents
Derivados tetraciclicos de indol como ligandos del receptor de 5-ht.Info
- Publication number
- MXPA04001201A MXPA04001201A MXPA04001201A MXPA04001201A MXPA04001201A MX PA04001201 A MXPA04001201 A MX PA04001201A MX PA04001201 A MXPA04001201 A MX PA04001201A MX PA04001201 A MXPA04001201 A MX PA04001201A MX PA04001201 A MXPA04001201 A MX PA04001201A
- Authority
- MX
- Mexico
- Prior art keywords
- receptor ligands
- indole derivatives
- tetracyclic indole
- compounds
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La presente invencion proporciona compuestos de formula (I), en donde R1, R2, R3, R4, Y, b, y c tienen cualquiera de los valores definidos en la especificacion, asi como composiciones farmaceuticas que comprenden los compuestos. La invencion tambien proporciona metodos terapeuticos para el tratamiento de enfermedades en donde la modulacion de la actividad 5-HT se desea, asi como un procedimiento e intermediarios utiles para la preparacion de compuestos de formula I.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31033201P | 2001-08-06 | 2001-08-06 | |
PCT/US2002/025073 WO2003028733A1 (en) | 2001-08-06 | 2002-08-05 | Tetracyclic indole derivatives as 5-ht receptor ligands |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04001201A true MXPA04001201A (es) | 2004-05-20 |
Family
ID=23202032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04001201A MXPA04001201A (es) | 2001-08-06 | 2002-08-05 | Derivados tetraciclicos de indol como ligandos del receptor de 5-ht. |
Country Status (7)
Country | Link |
---|---|
US (1) | US20030060462A1 (es) |
EP (1) | EP1423123A1 (es) |
JP (1) | JP2005504114A (es) |
BR (1) | BR0211562A (es) |
CA (1) | CA2453343A1 (es) |
MX (1) | MXPA04001201A (es) |
WO (1) | WO2003028733A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6994384B2 (en) * | 2002-11-20 | 2006-02-07 | General Electric Company | Integrated solitary bumper beam |
EP2248524A3 (en) | 2004-08-25 | 2011-03-09 | Takeda Pharmaceutical Company Limited | Preventives/remedies for stress urinary incontinence and method of screening the same |
EP2742936A1 (en) | 2006-05-16 | 2014-06-18 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound and use thereof |
EP2789338A3 (en) | 2007-11-15 | 2015-01-14 | Takeda Pharmaceutical Company Limited | Condensed pyridine derivate and use thereof |
JPWO2011071136A1 (ja) | 2009-12-11 | 2013-04-22 | アステラス製薬株式会社 | 線維筋痛症治療剤 |
EP2516396A1 (en) | 2009-12-23 | 2012-10-31 | Wayne State University | Therapeutic compounds |
EP3733204A4 (en) | 2017-12-27 | 2021-09-15 | Takeda Pharmaceutical Company Limited | THERAPEUTIC FOR EXERCISE INCONTINENCE AND STAIR INCONTINENCE |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5314900A (en) * | 1992-11-19 | 1994-05-24 | Merck Frosst Canada, Inc. | Aryl thiopyrano[2,3,4-C,D]indoles as inhibitors of leukotriene biosynthesis |
AR023574A1 (es) * | 1999-04-23 | 2002-09-04 | Pharmacia & Upjohn Co Llc | Compuestos de azepinindol tetraciclico,composiciones farmaceuticas y el uso de dichos compuestos para preparar un medicamento, e intermediarios |
IL145998A0 (en) * | 1999-06-15 | 2002-07-25 | Du Pont Pharm Co | Substituted heterocycle fused gamma-carbolines |
AU2001269781A1 (en) * | 2000-07-06 | 2002-01-21 | Pharmacia And Upjohn Company | Substituted 2,3,7,8,9,10,11,12-octahydroazepino(4,5-b)pyrano(3,2-e) indoles |
-
2002
- 2002-08-03 US US10/212,664 patent/US20030060462A1/en not_active Abandoned
- 2002-08-05 EP EP02800309A patent/EP1423123A1/en not_active Withdrawn
- 2002-08-05 BR BR0211562-0A patent/BR0211562A/pt not_active IP Right Cessation
- 2002-08-05 MX MXPA04001201A patent/MXPA04001201A/es unknown
- 2002-08-05 WO PCT/US2002/025073 patent/WO2003028733A1/en not_active Application Discontinuation
- 2002-08-05 JP JP2003532065A patent/JP2005504114A/ja not_active Withdrawn
- 2002-08-05 CA CA002453343A patent/CA2453343A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2453343A1 (en) | 2003-04-10 |
JP2005504114A (ja) | 2005-02-10 |
US20030060462A1 (en) | 2003-03-27 |
EP1423123A1 (en) | 2004-06-02 |
WO2003028733A1 (en) | 2003-04-10 |
BR0211562A (pt) | 2004-07-13 |
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