MXPA04000249A - Metodos para tratamiento de trastornos cognitivos y menopausicos con d-treo-metilfenidato. - Google Patents
Metodos para tratamiento de trastornos cognitivos y menopausicos con d-treo-metilfenidato.Info
- Publication number
- MXPA04000249A MXPA04000249A MXPA04000249A MXPA04000249A MXPA04000249A MX PA04000249 A MXPA04000249 A MX PA04000249A MX PA04000249 A MXPA04000249 A MX PA04000249A MX PA04000249 A MXPA04000249 A MX PA04000249A MX PA04000249 A MXPA04000249 A MX PA04000249A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- cognitive
- threo methylphenidate
- treatment
- methylphenidate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/903,803 US6486177B2 (en) | 1995-12-04 | 2001-07-12 | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| PCT/US2002/022039 WO2003005962A2 (en) | 2001-07-12 | 2002-07-11 | Methods for treatment of cognitive and menopausal disorders with d-threo methylphenidate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04000249A true MXPA04000249A (es) | 2004-05-04 |
Family
ID=25418099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04000249A MXPA04000249A (es) | 2001-07-12 | 2002-07-11 | Metodos para tratamiento de trastornos cognitivos y menopausicos con d-treo-metilfenidato. |
Country Status (10)
| Country | Link |
|---|---|
| US (7) | US6486177B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1411943A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2005520780A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20040029360A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002318302B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2453510C (cg-RX-API-DMAC7.html) |
| IL (1) | IL159313A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04000249A (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ565754A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003005962A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA98000395A (es) | 1995-07-14 | 2005-04-29 | Medeva Europ Ltd | Composicion que comprende d-treo-metilfenidato y otra droga. |
| US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
| US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US5837284A (en) * | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| US6962997B1 (en) * | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
| CA2412362A1 (en) * | 2000-06-20 | 2001-12-27 | Arthur L. Heerbst | Cox-2 inhibitors and the prevention of the side effects of radiation therapy |
| FR2823975B1 (fr) * | 2001-04-27 | 2003-05-30 | Sanofi Synthelabo | Nouvelle utilisation de pyridoindolone |
| JP4959335B2 (ja) * | 2003-10-08 | 2012-06-20 | マリンクロッド エルエルシー | メチルフェニデート溶液および関連する投与および製造方法 |
| US20050239830A1 (en) * | 2004-04-26 | 2005-10-27 | Vikram Khetani | Methods of diminishing co-abuse potential |
| WO2006012476A2 (en) * | 2004-07-22 | 2006-02-02 | Wyeth | Method for treating nervous system disorders and conditions |
| JP2008507552A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害および状態の治療方法 |
| JP2008507550A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害及び状態の処置方法 |
| US20060100243A1 (en) * | 2004-10-22 | 2006-05-11 | Mark Froimowitz | Methylphenidate analogs and methods of use thereof |
| EP1830648A4 (en) * | 2004-12-09 | 2008-03-12 | Celgene Corp | TREATMENT WITH D-THREO-METHYLPHENIDATE |
| CA2595400C (en) | 2005-01-20 | 2017-01-17 | Institute For Molecular Medicine, Inc. | Methylphenidate derivatives and their use in the treatment of angiogenic diseases and conditions |
| JP5274844B2 (ja) * | 2005-01-20 | 2013-08-28 | インスティチュート フォー モレキュラー メディスン インコーポレイテッド | メチルフェニデート誘導体を含む治療剤 |
| EP1904059A2 (en) * | 2005-07-21 | 2008-04-02 | Wyeth a Corporation of the State of Delaware | Method for treating nervous system disorders and conditions |
| KR101495146B1 (ko) | 2006-03-16 | 2015-02-24 | 트리스 파마 인코포레이티드 | 약물 - 이온교환 수지 복합체를 함유하는 변형 방출 제제 |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ,インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| US9345558B2 (en) | 2010-09-03 | 2016-05-24 | Ormco Corporation | Self-ligating orthodontic bracket and method of making same |
| EP2616055A1 (en) * | 2010-09-13 | 2013-07-24 | Tenera Therapeutics, LLC | Compositions for treating cancer treatment - related fatigue |
| US8287903B2 (en) | 2011-02-15 | 2012-10-16 | Tris Pharma Inc | Orally effective methylphenidate extended release powder and aqueous suspension product |
| DK2755498T3 (en) * | 2011-09-15 | 2018-05-22 | Friulchem Spa | COMPOSITION FOR ORAL ADMINISTRATION FOR ANIMALS AND PROCEDURE FOR OBTAINING |
| KR101312286B1 (ko) * | 2012-11-26 | 2013-09-27 | (주)비씨월드제약 | 즉시방출 및 조절방출 특성을 갖고 d-트레오-메틸페니데이트를 포함하는 약학 조성물 |
| US11590228B1 (en) | 2015-09-08 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine compositions |
| US11590081B1 (en) | 2017-09-24 | 2023-02-28 | Tris Pharma, Inc | Extended release amphetamine tablets |
| US12458592B1 (en) | 2017-09-24 | 2025-11-04 | Tris Pharma, Inc. | Extended release amphetamine tablets |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US49205A (en) * | 1865-08-01 | Improvement in machines for hulling grain | ||
| US32335A (en) * | 1861-05-14 | Island | ||
| US19535A (en) * | 1858-03-02 | Improvement in sewing-machines | ||
| US105134A (en) * | 1870-07-05 | Thomas sheehan | ||
| US2507631A (en) | 1944-01-19 | 1950-05-16 | Ciba Pharm Prod Inc | Pyridine and piperidine compounds and process of making same |
| GB589625A (en) | 1944-01-19 | 1947-06-25 | Chem Ind Basel | Manufacture of new pyridine and piperidine compounds |
| US2957880A (en) | 1953-12-23 | 1960-10-25 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| US2838519A (en) * | 1953-12-23 | 1958-06-10 | Ciba Pharm Prod Inc | Process for the conversion of stereoisomers |
| GB788226A (en) | 1953-12-23 | 1957-12-23 | Ciba Ltd | Stereoisomers of ª‡-phenyl-ª‡-piperidyl-(2)-acetic acid and process of making same |
| GB878167A (en) | 1958-11-17 | 1961-09-27 | Ciba Ltd | New acetic acid esters |
| SU466229A1 (ru) | 1973-01-23 | 1975-04-05 | Всесоюзный научно-исследовательский химико-фармацевтический институт им. С.Орджоникидзе | Способ получени гидрохлорида метилового эфира трео- -фенил- (пиперидил-2)-уксусной кислоты |
| US4137300A (en) | 1976-08-20 | 1979-01-30 | Ciba-Geigy Corporation | Sustained action dosage forms |
| US4410700A (en) * | 1980-07-03 | 1983-10-18 | The United States Of America As Represented By The Department Of Health And Human Services | Preparation of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines by optical resolution |
| DE3279999D1 (en) * | 1981-09-30 | 1989-11-30 | Nat Res Dev | Compositions comprising encapsulated particles |
| US4794001A (en) * | 1986-03-04 | 1988-12-27 | American Home Products Corporation | Formulations providing three distinct releases |
| US4904476A (en) * | 1986-03-04 | 1990-02-27 | American Home Products Corporation | Formulations providing three distinct releases |
| US4986987A (en) * | 1986-05-09 | 1991-01-22 | Alza Corporation | Pulsed drug delivery |
| US5114946A (en) | 1987-06-12 | 1992-05-19 | American Cyanamid Company | Transdermal delivery of pharmaceuticals |
| US4992445A (en) | 1987-06-12 | 1991-02-12 | American Cyanamid Co. | Transdermal delivery of pharmaceuticals |
| US5391381A (en) * | 1987-06-25 | 1995-02-21 | Alza Corporation | Dispenser capable of delivering plurality of drug units |
| US5236689A (en) * | 1987-06-25 | 1993-08-17 | Alza Corporation | Multi-unit delivery system |
| US5283193A (en) | 1988-06-27 | 1994-02-01 | Asahi Kasei Kogyo K.K. | Process for producing optically active α-substituted organic acid and microorganism and enzyme used therefor |
| SE509029C2 (sv) * | 1988-08-16 | 1998-11-30 | Ss Pharmaceutical Co | Långtidsverkande diklofenak-natriumpreparat |
| US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
| US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
| US5217718A (en) | 1989-08-18 | 1993-06-08 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| US5284769A (en) | 1989-10-16 | 1994-02-08 | Chiros Ltd. | Process for preparing a single enantiomer of a lactam using lactamase |
| US5362755A (en) | 1990-01-05 | 1994-11-08 | Sepracor, Inc. | Method for treating asthma using optically pure (R)-albuterol |
| US5229131A (en) * | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
| US5158777A (en) * | 1990-02-16 | 1992-10-27 | E. R. Squibb & Sons, Inc. | Captopril formulation providing increased duration of activity |
| JP2558396B2 (ja) * | 1990-06-28 | 1996-11-27 | 田辺製薬株式会社 | 放出制御型製剤 |
| US5104899A (en) | 1990-08-13 | 1992-04-14 | Sepracor, Inc. | Methods and compositions for treating depression using optically pure fluoxetine |
| US5156850A (en) * | 1990-08-31 | 1992-10-20 | Alza Corporation | Dosage form for time-varying patterns of drug delivery |
| US5232705A (en) * | 1990-08-31 | 1993-08-03 | Alza Corporation | Dosage form for time-varying patterns of drug delivery |
| US5160744A (en) * | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
| US5326570A (en) * | 1991-07-23 | 1994-07-05 | Pharmavene, Inc. | Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine |
| DE69229881T2 (de) * | 1991-10-04 | 1999-12-09 | Yoshitomi Pharmaceutical Industries, Ltd. | Tablette mit verzögerter freisetzung |
| DE69222006T2 (de) * | 1991-10-30 | 1998-01-22 | Glaxo Group Ltd | Mehrschichtzusammensetzungen enthaltend Histamin- oder Serotonin- Antagonisten |
| US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5223265A (en) * | 1992-01-10 | 1993-06-29 | Alza Corporation | Osmotic device with delayed activation of drug delivery |
| US5308348A (en) * | 1992-02-18 | 1994-05-03 | Alza Corporation | Delivery devices with pulsatile effect |
| US5331000A (en) | 1992-03-09 | 1994-07-19 | Sepracor Inc. | Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen |
| US5299121A (en) * | 1992-06-04 | 1994-03-29 | Medscreen, Inc. | Non-prescription drug medication screening system |
| US5512293A (en) * | 1992-07-23 | 1996-04-30 | Alza Corporation | Oral sustained release drug delivery device |
| CA2141572C (en) | 1992-08-03 | 2001-02-06 | James W. Young | Terfenadine metabolites and their optically pure isomers for treating allergic disorders |
| US5376384A (en) * | 1992-12-23 | 1994-12-27 | Kinaform Technology, Inc. | Delayed, sustained-release pharmaceutical preparation |
| JP3091618B2 (ja) | 1993-01-29 | 2000-09-25 | 四郎 小林 | 開環重合法および開環重合用酵素触媒 |
| JP2916978B2 (ja) * | 1993-08-25 | 1999-07-05 | エスエス製薬株式会社 | 放出開始制御型製剤 |
| US5500227A (en) * | 1993-11-23 | 1996-03-19 | Euro-Celtique, S.A. | Immediate release tablet cores of insoluble drugs having sustained-release coating |
| US5567441A (en) * | 1995-03-24 | 1996-10-22 | Andrx Pharmaceuticals Inc. | Diltiazem controlled release formulation |
| IT1276689B1 (it) | 1995-06-09 | 1997-11-03 | Applied Pharma Res | Forma farmaceutica solida ad uso orale |
| MXPA98000395A (es) | 1995-07-14 | 2005-04-29 | Medeva Europ Ltd | Composicion que comprende d-treo-metilfenidato y otra droga. |
| GB9514451D0 (en) | 1995-07-14 | 1995-09-13 | Chiroscience Ltd | Sustained-release formulation |
| JPH11509227A (ja) | 1995-07-14 | 1999-08-17 | カイロサイエンス・リミテッド | d−トレオ−メチルフェニデートの治療的使用 |
| US5733756A (en) | 1996-01-05 | 1998-03-31 | Celgene Corporation | Lactams and processes for stereoselective enrichment of lactams, amides, and esters |
| US6355656B1 (en) * | 1995-12-04 | 2002-03-12 | Celgene Corporation | Phenidate drug formulations having diminished abuse potential |
| US5837284A (en) * | 1995-12-04 | 1998-11-17 | Mehta; Atul M. | Delivery of multiple doses of medications |
| US5922736A (en) * | 1995-12-04 | 1999-07-13 | Celegene Corporation | Chronic, bolus administration of D-threo methylphenidate |
| US6486177B2 (en) * | 1995-12-04 | 2002-11-26 | Celgene Corporation | Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate |
| US5908850A (en) | 1995-12-04 | 1999-06-01 | Celgene Corporation | Method of treating attention deficit disorders with d-threo methylphenidate |
| MX9805870A (cg-RX-API-DMAC7.html) | 1996-01-22 | 1999-01-31 | ||
| US6242464B1 (en) | 1996-01-22 | 2001-06-05 | Chiroscience Limited | Single isomer methylphenidate and resolution process |
| JP2000504008A (ja) | 1996-02-02 | 2000-04-04 | メデバ・ユアラプ・リミテッド | D―トレオ―(r,r)―メチルフェニデートの調製およびエピメリゼーションによる不要エナンチオマーリサイクルの方法 |
| GB9604943D0 (en) * | 1996-03-08 | 1996-05-08 | Chiroscience Ltd | Resolution |
| DE69710051T2 (de) | 1996-03-08 | 2002-08-14 | Medeva Europe Ltd., Slough | Auflösungsverfahren von threo-methylphenidate |
| GB9606417D0 (en) | 1996-03-27 | 1996-06-05 | Chiroscience Ltd | Asymmetric cyclisation |
| ES2264173T3 (es) | 1996-11-25 | 2006-12-16 | Alza Corporation | Forma de dosificacion para suministrar una dosis creciente. |
| CZ206299A3 (cs) | 1996-12-13 | 1999-09-15 | Medeva Europe Limited | Způsob přípravy enantiomerně obohaceného THREO-metalfenidátu |
| GB9700912D0 (en) | 1997-01-17 | 1997-03-05 | Chiroscience Ltd | Resolution |
| US5965734A (en) * | 1997-01-31 | 1999-10-12 | Celgene Corporation | Processes and intermediates for preparing 2-substituted piperidine stereoisomers |
| US6962997B1 (en) * | 1997-05-22 | 2005-11-08 | Celgene Corporation | Process and intermediates for resolving piperidyl acetamide steroisomers |
| US5936091A (en) * | 1997-05-22 | 1999-08-10 | Celgene Corporation | Processes and intermediates for resolving piperidyl acetamide stereoisomers |
| PL205109B1 (pl) * | 1998-11-02 | 2010-03-31 | Elan Pharma Int Ltd | Wielocząstkowa kompozycja metylofenidatu o modyfikowanym uwalnianiu i jej zastosowanie |
| US6395752B1 (en) | 1999-03-04 | 2002-05-28 | Pharmaquest Limited | Method of treating depression using 1-threo-methylphenidate |
| US6127385A (en) | 1999-03-04 | 2000-10-03 | Pharmaquest Limited | Method of treating depression using l-threo-methylphenidate |
| GB9913458D0 (en) | 1999-06-09 | 1999-08-11 | Medeva Europ Ltd | The therapeutic use of d-threo-methylphenidate |
| WO2001043730A2 (en) | 1999-12-17 | 2001-06-21 | Medeva Europe Limited | The treatment of convulsive states |
| US6221883B1 (en) | 2000-04-12 | 2001-04-24 | Ross Baldessarini | Method of dopamine inhibition using l-threo-methylphenidate |
| US20020132793A1 (en) * | 2000-08-28 | 2002-09-19 | Mel Epstein | Use of methylphenidate compounds to enhance memory |
| US6344215B1 (en) | 2000-10-27 | 2002-02-05 | Eurand America, Inc. | Methylphenidate modified release formulations |
| US6359139B1 (en) * | 2000-11-07 | 2002-03-19 | Celgene Corporation | Methods for production of piperidyl acetamide stereoisomers |
-
2001
- 2001-07-12 US US09/903,803 patent/US6486177B2/en not_active Expired - Fee Related
-
2002
- 2002-07-11 CA CA2453510A patent/CA2453510C/en not_active Expired - Fee Related
- 2002-07-11 EP EP02748129A patent/EP1411943A4/en not_active Withdrawn
- 2002-07-11 IL IL15931302A patent/IL159313A0/xx unknown
- 2002-07-11 JP JP2003511771A patent/JP2005520780A/ja active Pending
- 2002-07-11 WO PCT/US2002/022039 patent/WO2003005962A2/en not_active Ceased
- 2002-07-11 MX MXPA04000249A patent/MXPA04000249A/es active IP Right Grant
- 2002-07-11 NZ NZ565754A patent/NZ565754A/en not_active IP Right Cessation
- 2002-07-11 NZ NZ530211A patent/NZ530211A/en not_active IP Right Cessation
- 2002-07-11 KR KR10-2004-7000312A patent/KR20040029360A/ko not_active Ceased
- 2002-07-11 AU AU2002318302A patent/AU2002318302B2/en not_active Ceased
- 2002-07-16 US US10/195,974 patent/US7115631B2/en not_active Expired - Fee Related
-
2004
- 2004-04-08 US US10/820,397 patent/US20040204456A1/en not_active Abandoned
-
2006
- 2006-04-11 US US11/402,385 patent/US20060183774A1/en not_active Abandoned
-
2009
- 2009-12-17 US US12/640,734 patent/US20100093797A1/en not_active Abandoned
-
2011
- 2011-06-30 US US13/172,977 patent/US20110257227A1/en not_active Abandoned
-
2012
- 2012-10-26 US US13/661,472 patent/US20130053414A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ530211A (en) | 2008-04-30 |
| US20020022640A1 (en) | 2002-02-21 |
| US7115631B2 (en) | 2006-10-03 |
| AU2002318302B2 (en) | 2007-03-15 |
| EP1411943A2 (en) | 2004-04-28 |
| IL159313A0 (en) | 2004-06-01 |
| US20040204456A1 (en) | 2004-10-14 |
| KR20040029360A (ko) | 2004-04-06 |
| NZ565754A (en) | 2009-05-31 |
| CA2453510C (en) | 2012-03-20 |
| US20130053414A1 (en) | 2013-02-28 |
| WO2003005962A2 (en) | 2003-01-23 |
| EP1411943A4 (en) | 2005-09-28 |
| US20060183774A1 (en) | 2006-08-17 |
| CA2453510A1 (en) | 2003-01-23 |
| US20110257227A1 (en) | 2011-10-20 |
| AU2002318302C1 (en) | 2003-01-29 |
| US20100093797A1 (en) | 2010-04-15 |
| JP2005520780A (ja) | 2005-07-14 |
| US6486177B2 (en) | 2002-11-26 |
| WO2003005962A3 (en) | 2003-06-12 |
| US20020198234A1 (en) | 2002-12-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MXPA04000249A (es) | Metodos para tratamiento de trastornos cognitivos y menopausicos con d-treo-metilfenidato. | |
| AR055810A1 (es) | Uso de inhibidores de acetilcolinesterasa e inhibidores de la produccion de beta-app o acumulacion de a-beta | |
| IL280818B (en) | A methods of producing alpha-galactosidase preparations | |
| ATE475418T1 (de) | O-methylierte rapamycinderivate zur milderung oder vermeidung lymphoproliferativer erkrankungen | |
| MX9704793A (es) | Metodos y composiciones para tratar rinitis alergica y otros trastornos usando descarboetoxiloratadina. | |
| MXPA04006280A (es) | Compuestos espiroazaciclicos como moduladores de receptor de monoamina. | |
| ATE328588T1 (de) | Behandlung von nicotinsucht und sucht bedingtem verhalten | |
| PL347469A1 (en) | Use of certain drugs for treating nerve root injury | |
| UA85055C2 (ru) | Применение ингибиторов миостатика (gdf8) в сочетании с кортикостероидами для лечения нервно-мышечных заболеваний | |
| WO2002038142A3 (en) | Serotonergic compositions and methods for treatment of mild cognitive impairment | |
| DE69833971D1 (de) | Verfahren zur behandlung von alzheimerschen krankheit | |
| WO2006042249A3 (en) | Methods and compositions for treating migraine pain | |
| MY180733A (en) | Method of using ?-hydroxy-?-methybutyrate | |
| IL144643A0 (en) | Jak-3 inhibitors for treating allergic disorders | |
| PL330496A1 (en) | Methods of and compositions for treating and preventing tumours, disorders associated with tumours as well as cachexy | |
| AP2002002596A0 (en) | Piperazine and piperidine derivatives. | |
| WO2003015713A3 (en) | Treatment of glial tumors with glutamate antagonists | |
| TN2011000228A1 (en) | Method for treating or preventing thrombosis using dabigatran etexilate or a salt thereof with improved safety profile over conventional warfarin therapy | |
| PL338555A1 (en) | Method of preventing or treating oestrogen-dependent diseases and disorders | |
| MXPA02004701A (es) | Sales de hidroxieicosatetraenoato, composiciones y metodos de uso para tratar trastornos de resequedad en los ojos. | |
| NZ332585A (en) | Carboxamide derivatives of pyrrolidine, piperidine and hexahydroazepine for the treatment of thrombosis disorders | |
| WO2004062623A3 (en) | Method of treating functional bowel disorders | |
| WO2002062777A3 (en) | Amino ceramide-like compounds and therapeutic methods of use | |
| IL144315A0 (en) | Methods of using a neurotrophin and its analogues for the treatment of gastrointestinal hypomotility disorders | |
| ATE541565T1 (de) | Topische verwendung von muskarinischen und opioiden mitteln zur behandlung von tinnitus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |