MXPA04000211A - Granulados que contienen substancias liposolubles y un proceso para la preparacion de los mismos. - Google Patents

Granulados que contienen substancias liposolubles y un proceso para la preparacion de los mismos.

Info

Publication number
MXPA04000211A
MXPA04000211A MXPA04000211A MXPA04000211A MXPA04000211A MX PA04000211 A MXPA04000211 A MX PA04000211A MX PA04000211 A MXPA04000211 A MX PA04000211A MX PA04000211 A MXPA04000211 A MX PA04000211A MX PA04000211 A MXPA04000211 A MX PA04000211A
Authority
MX
Mexico
Prior art keywords
preparation
granulates
water
substances
granulates containing
Prior art date
Application number
MXPA04000211A
Other languages
English (en)
Inventor
Reiner Alberto
Original Assignee
Ipsen Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Spa filed Critical Ipsen Spa
Publication of MXPA04000211A publication Critical patent/MXPA04000211A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Edible Oils And Fats (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe un proceso para la preparacion de granulados que contienen substancias liposolubles e hidrofobicas, preferentemente substancias esteroidales, y que exhiben rapida y excelente dispersion en agua. El proceso comprende: a) la dispersion de la substancia (A) en agua en la presencia de un surfactante (B), b) la incorporacion de un excipiente solido polihidroxilado soluble en agua (C) en la dispersion acuosa hasta que una masa pastosa granulada sea obtenida y c) la granulacion de la masa. Los granulados asi obtenidos son adecuados para la preparacion, al momento de su uso, de suspensiones acuosas homogeneas y estables que se utilizan para propositos nutricionales, cosmeticos o, preferentemente, farmaceuticos.
MXPA04000211A 2001-07-11 2002-07-09 Granulados que contienen substancias liposolubles y un proceso para la preparacion de los mismos. MXPA04000211A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202657A EP1275377B1 (en) 2001-07-11 2001-07-11 Granulates containing liposoluble substances and process of preparation thereof
PCT/EP2002/007636 WO2003005989A2 (en) 2001-07-11 2002-07-09 Granulates containing liposoluble substances and a process for the preparation thereof

Publications (1)

Publication Number Publication Date
MXPA04000211A true MXPA04000211A (es) 2005-03-07

Family

ID=8180628

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04000211A MXPA04000211A (es) 2001-07-11 2002-07-09 Granulados que contienen substancias liposolubles y un proceso para la preparacion de los mismos.

Country Status (21)

Country Link
US (1) US7615547B2 (es)
EP (1) EP1275377B1 (es)
JP (1) JP2004536118A (es)
KR (1) KR100877628B1 (es)
AT (1) ATE243028T1 (es)
AU (1) AU2002328866B2 (es)
BR (1) BR0211081A (es)
CA (1) CA2452386C (es)
DE (1) DE60100389T2 (es)
DK (1) DK1275377T3 (es)
ES (1) ES2199202T3 (es)
HR (1) HRP20040010A2 (es)
IL (1) IL159346A0 (es)
MX (1) MXPA04000211A (es)
NO (1) NO20040043L (es)
NZ (1) NZ530473A (es)
PL (1) PL204963B1 (es)
PT (1) PT1275377E (es)
RU (1) RU2288704C2 (es)
WO (1) WO2003005989A2 (es)
ZA (1) ZA200309680B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050080486A1 (en) 2000-11-29 2005-04-14 Fallin T. Wade Facet joint replacement
US6579319B2 (en) 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US8419770B2 (en) 2003-12-10 2013-04-16 Gmedelaware 2 Llc Spinal facet implants with mating articulating bearing surface and methods of use
US8470344B2 (en) 2005-12-09 2013-06-25 Teva Pharmaceutical Industries Ltd. Aqueous dispersions and solutions of difficult to dissolve materials and methods of their preparation
MX2009006105A (es) 2006-12-22 2009-06-18 Yuhan Corp Dispersion solida que contiene revaprazan y proceso para su preparacion.
JP6216327B2 (ja) * 2011-12-22 2017-10-18 ライフ テクノロジーズ コーポレーション 細胞培地および方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． ステロイドホルモン薬学的組成物
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11534421B2 (en) * 2017-06-23 2022-12-27 Nordiccan A/S Cannabinoid pouch
CN108309933A (zh) * 2018-03-19 2018-07-24 青岛国海生物制药有限公司 一种口服醋酸甲地孕酮纳米混悬液及其制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3610037A1 (de) * 1986-03-21 1987-09-24 Schering Ag Nifedipinkombinationspraeparat
JPH0449232A (ja) 1990-06-15 1992-02-18 Fujisawa Pharmaceut Co Ltd 懸濁用組成物または懸濁液並びにそれらの製造法
US5338732A (en) * 1991-06-18 1994-08-16 Bristol-Myers Squibb Company Megestrol acetate formulation
US5395627A (en) * 1992-09-04 1995-03-07 Akzo N.V. Pharmaceutical granulate
FR2702968B1 (fr) 1993-03-23 1995-06-23 Lafon Labor Procédé de préparation de particules renfermant un ingrédient actif par extrusion et lyophilisation .
JP3844491B2 (ja) 1993-10-01 2006-11-15 シンテックス（ユー・エス・エイ）インコーポレイテッド ミコフェノール酸モフェチル高用量経口用懸濁剤
US5976570A (en) * 1993-12-21 1999-11-02 Applied Analytical Industries, Inc. Method for preparing low dose pharmaceutical products
FR2730163B1 (fr) 1995-02-03 1997-04-04 Jouveinal Lab Nouvelle composition pharmaceutique contenant la trimebutine et son procede de preparation
US20020028248A1 (en) 1996-03-14 2002-03-07 Takayuki Tsukada Rapid-release microdispersible ecadotril preparation
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
DE19637082A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
TW486370B (en) * 1996-12-25 2002-05-11 Yamanouchi Pharma Co Ltd Rapidly disintegrable pharmaceutical composition
US6028065A (en) * 1998-04-20 2000-02-22 Pharmaceutical Resources, Inc. Flocculated suspension of megestrol acetate
WO2000030616A1 (en) 1998-11-20 2000-06-02 Rtp Pharma Inc. Dispersible phospholipid stabilized microparticles
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form

Also Published As

Publication number Publication date
DE60100389D1 (de) 2003-07-24
CA2452386C (en) 2011-01-18
RU2288704C2 (ru) 2006-12-10
ATE243028T1 (de) 2003-07-15
EP1275377A1 (en) 2003-01-15
JP2004536118A (ja) 2004-12-02
NZ530473A (en) 2006-02-24
KR20040018440A (ko) 2004-03-03
PL369294A1 (en) 2005-04-18
RU2004103853A (ru) 2005-03-27
KR100877628B1 (ko) 2009-01-07
BR0211081A (pt) 2004-12-14
ES2199202T3 (es) 2004-02-16
US20040009232A1 (en) 2004-01-15
WO2003005989A2 (en) 2003-01-23
AU2002328866B2 (en) 2007-02-15
CA2452386A1 (en) 2003-01-23
US7615547B2 (en) 2009-11-10
HRP20040010B1 (es) 2007-01-31
PT1275377E (pt) 2003-11-28
DK1275377T3 (da) 2003-10-06
WO2003005989A3 (en) 2003-05-01
DE60100389T2 (de) 2004-05-19
HRP20040010A2 (en) 2004-06-30
EP1275377B1 (en) 2003-06-18
ZA200309680B (en) 2004-12-22
IL159346A0 (en) 2004-06-01
NO20040043L (no) 2004-01-06
PL204963B1 (pl) 2010-02-26

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