MXPA04000034A - Genes regulatorios de celulas t metodos para utilizar los mismos. - Google Patents
Genes regulatorios de celulas t metodos para utilizar los mismos.Info
- Publication number
- MXPA04000034A MXPA04000034A MXPA04000034A MXPA04000034A MXPA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A
- Authority
- MX
- Mexico
- Prior art keywords
- tim
- thr
- leu
- ser
- val
- Prior art date
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Zoology (AREA)
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- Pulmonology (AREA)
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- Biotechnology (AREA)
- Cell Biology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
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- General Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30234401P | 2001-06-29 | 2001-06-29 | |
| PCT/US2002/020890 WO2003002722A2 (en) | 2001-06-29 | 2002-07-01 | T cell regulatory genes and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04000034A true MXPA04000034A (es) | 2005-11-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04000034A MXPA04000034A (es) | 2001-06-29 | 2002-07-01 | Genes regulatorios de celulas t metodos para utilizar los mismos. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7553939B2 (https=) |
| EP (1) | EP1406653A4 (https=) |
| JP (3) | JP4572276B2 (https=) |
| KR (1) | KR20040014997A (https=) |
| CN (1) | CN1538853A (https=) |
| CA (1) | CA2452196A1 (https=) |
| IL (1) | IL159627A0 (https=) |
| MX (1) | MXPA04000034A (https=) |
| NZ (1) | NZ530451A (https=) |
| WO (1) | WO2003002722A2 (https=) |
| ZA (1) | ZA200400013B (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1997044460A1 (en) * | 1996-05-24 | 1997-11-27 | Biogen, Inc. | Modulators of tissue regeneration |
| DE60137934D1 (de) * | 2000-06-16 | 2009-04-23 | Biogen Idec Inc | Renale regulatorische elemente und deren verwendung |
| EP1401869B1 (en) * | 2001-06-01 | 2007-12-26 | Biogen Idec MA Inc. | Molecules and methods for inhibiting shedding of kim-1 |
| EP1406653A4 (en) * | 2001-06-29 | 2005-05-04 | Univ Leland Stanford Junior | T CELL REGULATION GENES AND METHOD OF USE THEREOF |
| US7838220B2 (en) | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
| US8709412B2 (en) | 2001-06-29 | 2014-04-29 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of TIM receptor activity in combination with cytoreductive therapy |
| AU2003303082B2 (en) * | 2002-01-30 | 2009-07-02 | Dana-Farber Cancer Institute, Inc. | Compositions and methods related to TIM-3, a Th1-specific cell surface molecule |
| CA2479732A1 (en) * | 2002-03-19 | 2003-10-02 | Curagen Corporation | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| DK1585546T3 (da) * | 2002-12-30 | 2008-12-08 | Biogen Idec Inc | KIM- 1- Antagonister og Brug til at Modulere Immunsystem |
| AU2013242840B2 (en) * | 2003-03-19 | 2017-01-19 | Amgen Fremont Inc. | Antibodies Against T Cell Immunoglobulin Domain and Mucin Domain 1 (TIM-1) Antigen and Uses Thereof |
| DK1613750T3 (en) * | 2003-03-19 | 2016-01-18 | Amgen Fremont Inc | ANTIBODIES TO T CELL AND MUCINDO immunoglobulin-binding domain 1 (TIM-1) antigen and uses thereof |
| MXPA06003686A (es) * | 2003-10-03 | 2007-03-01 | Brigham & Womens Hospital | Ligandos tim-3 y sus metodos. |
| US20050197292A1 (en) * | 2004-01-30 | 2005-09-08 | Glennda Smithson | Compositions and methods for treating T-cell mediated pathological conditions |
| TW200539890A (en) * | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| AU2005231685A1 (en) * | 2004-03-24 | 2005-10-20 | Telos Pharmaceuticals Llc | Compositions as adjuvants to improve immune responses to vaccines and methods of use |
| EP2290071B1 (en) | 2004-05-28 | 2014-12-31 | Asuragen, Inc. | Methods and compositions involving microRNA |
| CA2857881A1 (en) | 2004-11-12 | 2006-12-28 | Asuragen, Inc. | Methods and compositions involving mirna and mirna inhibitor molecules |
| CN1778816B (zh) * | 2004-11-22 | 2010-07-07 | 中国人民解放军第二军医大学 | 人细胞表面膜分子及用途 |
| EP2251037B1 (en) | 2005-03-02 | 2015-01-14 | Biogen Idec MA Inc. | KIM-1 antibodies for treatment of TH1/TH2-mediated conditions |
| KR100746312B1 (ko) * | 2005-03-14 | 2007-08-03 | 한국화학연구원 | 수용성 산화철 나노 입자 및 이의 제조방법 |
| WO2008036765A2 (en) * | 2006-09-19 | 2008-03-27 | Asuragen, Inc. | Micrornas differentially expressed in pancreatic diseases and uses thereof |
| US8361714B2 (en) | 2007-09-14 | 2013-01-29 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
| US8071562B2 (en) | 2007-12-01 | 2011-12-06 | Mirna Therapeutics, Inc. | MiR-124 regulated genes and pathways as targets for therapeutic intervention |
| EP2268832A2 (en) * | 2008-03-06 | 2011-01-05 | Asuragen, INC. | Microrna markers for recurrence of colorectal cancer |
| US8258111B2 (en) | 2008-05-08 | 2012-09-04 | The Johns Hopkins University | Compositions and methods related to miRNA modulation of neovascularization or angiogenesis |
| WO2010095461A1 (ja) * | 2009-02-20 | 2010-08-26 | 国立大学法人東京大学 | 新規モノクローナル抗体、並びにその使用 |
| WO2013040251A2 (en) | 2011-09-13 | 2013-03-21 | Asurgen, Inc. | Methods and compositions involving mir-135b for distinguishing pancreatic cancer from benign pancreatic disease |
| JP6196034B2 (ja) * | 2012-12-20 | 2017-09-13 | ライオン株式会社 | 高血糖リスク判定用マーカーペプチドおよびその用途 |
| US10570204B2 (en) | 2013-09-26 | 2020-02-25 | The Medical College Of Wisconsin, Inc. | Methods for treating hematologic cancers |
| SG10201900002QA (en) | 2014-01-24 | 2019-02-27 | Dana Farber Cancer Institue Inc | Antibody molecules to pd-1 and uses thereof |
| EP3099717B1 (en) | 2014-01-31 | 2019-03-27 | Novartis AG | Antibody molecules to tim-3 and uses thereof |
| US20150259420A1 (en) | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
| ES2771926T3 (es) | 2014-09-13 | 2020-07-07 | Novartis Ag | Terapias de combinación |
| EP3283508B1 (en) | 2015-04-17 | 2021-03-17 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| DK3317301T3 (da) | 2015-07-29 | 2021-06-28 | Immutep Sas | Kombinationsterapier omfattende antistofmolekyler mod lag-3 |
| TWI726920B (zh) * | 2015-10-14 | 2021-05-11 | 耶魯大學 | 基因體規模的ｔ細胞活性陣列、其製造方法、其用於辨識免疫調節因子的方法及其用途 |
| IL262365B2 (en) | 2016-04-15 | 2024-11-01 | Alpine Immune Sciences Inc | Immunomodulatory proteins ICOS ligand variants and uses thereof |
| TWI781934B (zh) | 2016-05-27 | 2022-11-01 | 美商艾吉納斯公司 | 抗-tim-3抗體及其使用方法 |
| MY200602A (en) | 2016-07-14 | 2024-01-04 | Bristol Myers Squibb Co | Antibodies against tim3 and uses thereof |
| US11203637B2 (en) * | 2016-08-26 | 2021-12-21 | Beigene, Ltd. | Anti-Tim-3 antibodies and use thereof |
| EP4089116A1 (en) | 2016-09-27 | 2022-11-16 | Cero Therapeutics, Inc. | Chimeric engulfment receptor molecules |
| WO2018086594A1 (en) | 2016-11-11 | 2018-05-17 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric tim-3 |
| BR112019020959A2 (pt) * | 2017-04-10 | 2020-05-05 | Immatics Biotechnologies Gmbh | peptídeos e combinações dos mesmos para uso na imunoterapia contra câncer |
| EP3688032B1 (en) | 2017-09-26 | 2025-11-05 | Cero Therapeutics Holdings, Inc. | Chimeric engulfment receptor molecules and methods of use |
| CN108037292A (zh) * | 2017-11-29 | 2018-05-15 | 天津市湖滨盘古基因科学发展有限公司 | 一种人的磷脂酰丝氨酸受体突变蛋白及其应用 |
| WO2019191334A1 (en) | 2018-03-28 | 2019-10-03 | Cero Therapeutics, Inc. | Chimeric tim4 receptors and uses thereof |
| JP7444781B2 (ja) | 2018-03-28 | 2024-03-06 | セロ・セラピューティクス・インコーポレイテッド | 細胞免疫療法組成物およびその使用 |
| WO2020113141A2 (en) | 2018-11-30 | 2020-06-04 | Alpine Immune Sciences, Inc. | Cd86 variant immunomodulatory proteins and uses thereof |
| CN110412263B (zh) * | 2019-07-31 | 2023-01-31 | 中国农业科学院茶叶研究所 | 一种快速高效的茶树质体型谷氨酰胺合成酶基因定位方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| WO1997044460A1 (en) * | 1996-05-24 | 1997-11-27 | Biogen, Inc. | Modulators of tissue regeneration |
| US5986059A (en) * | 1996-06-14 | 1999-11-16 | Bayer Corporation | T-cell selective interleukin-4 agonists |
| US7060458B1 (en) * | 1997-08-14 | 2006-06-13 | Wyeth | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| CA2319129A1 (en) * | 1998-01-30 | 1999-08-05 | Human Genome Sciences, Inc. | 67 human secreted proteins |
| CA2324648C (en) * | 1998-03-27 | 2013-02-26 | Prolume, Ltd. | Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items |
| WO2002081517A2 (en) * | 2001-01-19 | 2002-10-17 | Curagen Corporation | Novel polypeptides and nucleic acids encoded thereby |
| EP1406653A4 (en) * | 2001-06-29 | 2005-05-04 | Univ Leland Stanford Junior | T CELL REGULATION GENES AND METHOD OF USE THEREOF |
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- 2002-07-01 KR KR10-2003-7003079A patent/KR20040014997A/ko not_active Ceased
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- 2002-07-01 WO PCT/US2002/020890 patent/WO2003002722A2/en not_active Ceased
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Also Published As
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| JP2007000146A (ja) | 2007-01-11 |
| JP2010057492A (ja) | 2010-03-18 |
| JP4351233B2 (ja) | 2009-10-28 |
| JP2005500039A (ja) | 2005-01-06 |
| EP1406653A2 (en) | 2004-04-14 |
| CN1538853A (zh) | 2004-10-20 |
| CA2452196A1 (en) | 2003-01-09 |
| US20090252737A1 (en) | 2009-10-08 |
| KR20040014997A (ko) | 2004-02-18 |
| IL159627A0 (en) | 2004-06-01 |
| JP4572276B2 (ja) | 2010-11-04 |
| WO2003002722A3 (en) | 2003-04-03 |
| EP1406653A4 (en) | 2005-05-04 |
| WO2003002722A2 (en) | 2003-01-09 |
| NZ530451A (en) | 2008-04-30 |
| WO2003002722A9 (en) | 2004-04-15 |
| US20030124114A1 (en) | 2003-07-03 |
| US7553939B2 (en) | 2009-06-30 |
| ZA200400013B (en) | 2006-05-31 |
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