MXPA04000034A - Genes regulatorios de celulas t metodos para utilizar los mismos. - Google Patents
Genes regulatorios de celulas t metodos para utilizar los mismos.Info
- Publication number
- MXPA04000034A MXPA04000034A MXPA04000034A MXPA04000034A MXPA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A MX PA04000034 A MXPA04000034 A MX PA04000034A
- Authority
- MX
- Mexico
- Prior art keywords
- tim
- thr
- leu
- ser
- val
- Prior art date
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30234401P | 2001-06-29 | 2001-06-29 | |
| PCT/US2002/020890 WO2003002722A2 (en) | 2001-06-29 | 2002-07-01 | T cell regulatory genes and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
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| MXPA04000034A true MXPA04000034A (es) | 2005-11-23 |
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| MXPA04000034A MXPA04000034A (es) | 2001-06-29 | 2002-07-01 | Genes regulatorios de celulas t metodos para utilizar los mismos. |
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| EP (1) | EP1406653A4 (enExample) |
| JP (3) | JP4572276B2 (enExample) |
| KR (1) | KR20040014997A (enExample) |
| CN (1) | CN1538853A (enExample) |
| CA (1) | CA2452196A1 (enExample) |
| IL (1) | IL159627A0 (enExample) |
| MX (1) | MXPA04000034A (enExample) |
| NZ (1) | NZ530451A (enExample) |
| WO (1) | WO2003002722A2 (enExample) |
| ZA (1) | ZA200400013B (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2258793T5 (es) * | 1996-05-24 | 2010-01-25 | Biogen Idec Ma Inc. | Moduladores de la regeneracion tisular. |
| NZ523475A (en) * | 2000-06-16 | 2004-09-24 | Biogen Inc | Renal regulatory elements and methods of use thereof |
| JP4527394B2 (ja) * | 2001-06-01 | 2010-08-18 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｋｉｍ−１の分断を阻害するための分子および方法 |
| US8709412B2 (en) * | 2001-06-29 | 2014-04-29 | The Board Of Trustees Of The Leland Stanford Junior University | Modulation of TIM receptor activity in combination with cytoreductive therapy |
| US7838220B2 (en) | 2001-06-29 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | T cell regulatory genes associated with immune disease |
| MXPA04000034A (es) * | 2001-06-29 | 2005-11-23 | Univ Leland Stanford Junior | Genes regulatorios de celulas t metodos para utilizar los mismos. |
| JP4694128B2 (ja) | 2002-01-30 | 2011-06-08 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | ＴＩＭ−３、Ｔｈ１特異的細胞表面分子に関連した組成物および方法 |
| EP1576169B1 (en) * | 2002-03-19 | 2016-08-10 | Celldex Therapeutics, Inc. | Therapeutic polypeptides and methods of use |
| PT1585546E (pt) * | 2002-12-30 | 2008-11-14 | Biogen Idec Inc | Antagonistas de kim-1 e sua utilização para modular o sistema imunitário |
| AU2004224390A1 (en) * | 2003-03-19 | 2004-10-07 | Abgenix, Inc. | Antibodies against T cell immunoglobulin domain and mucin domain 1 (TIM-1) antigen and uses thereof |
| AU2013242840B2 (en) * | 2003-03-19 | 2017-01-19 | Amgen Fremont Inc. | Antibodies Against T Cell Immunoglobulin Domain and Mucin Domain 1 (TIM-1) Antigen and Uses Thereof |
| KR20060089732A (ko) | 2003-10-03 | 2006-08-09 | 브라이엄 앤드 위민즈 하스피틀 | Ｔｉｍ-3 리간드 및 그의 방법 |
| US20050197292A1 (en) * | 2004-01-30 | 2005-09-08 | Glennda Smithson | Compositions and methods for treating T-cell mediated pathological conditions |
| TW200539890A (en) * | 2004-03-12 | 2005-12-16 | Brigham & Womens Hospital | Methods of modulating immune responses by modulating tim-1, tim-2 and tim-4 function |
| AU2005231685A1 (en) * | 2004-03-24 | 2005-10-20 | Telos Pharmaceuticals Llc | Compositions as adjuvants to improve immune responses to vaccines and methods of use |
| US7888010B2 (en) | 2004-05-28 | 2011-02-15 | Asuragen, Inc. | Methods and compositions involving microRNA |
| EP2808389A1 (en) | 2004-11-12 | 2014-12-03 | Asuragen, Inc. | Methods and compositions involving MIRNA and MIRNA inhibitor molecules |
| CN1778816B (zh) * | 2004-11-22 | 2010-07-07 | 中国人民解放军第二军医大学 | 人细胞表面膜分子及用途 |
| AU2006218489B2 (en) * | 2005-03-02 | 2011-02-24 | Biogen Ma Inc. | KIM-1 antibodies for treatment of Th2-mediated conditions |
| KR100746312B1 (ko) * | 2005-03-14 | 2007-08-03 | 한국화학연구원 | 수용성 산화철 나노 입자 및 이의 제조방법 |
| JP5520605B2 (ja) * | 2006-09-19 | 2014-06-11 | アシュラジェン インコーポレイテッド | 膵臓疾患で差次的に発現されるマイクロｒｎａおよびその使用 |
| EP2198050A1 (en) | 2007-09-14 | 2010-06-23 | Asuragen, INC. | Micrornas differentially expressed in cervical cancer and uses thereof |
| WO2009070805A2 (en) | 2007-12-01 | 2009-06-04 | Asuragen, Inc. | Mir-124 regulated genes and pathways as targets for therapeutic intervention |
| EP2268832A2 (en) * | 2008-03-06 | 2011-01-05 | Asuragen, INC. | Microrna markers for recurrence of colorectal cancer |
| EP2990487A1 (en) | 2008-05-08 | 2016-03-02 | Asuragen, INC. | Compositions and methods related to mirna modulation of neovascularization or angiogenesis |
| JP5800299B2 (ja) * | 2009-02-20 | 2015-10-28 | 国立大学法人 東京大学 | 新規モノクローナル抗体、並びにその使用 |
| US9644241B2 (en) | 2011-09-13 | 2017-05-09 | Interpace Diagnostics, Llc | Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease |
| JP6196034B2 (ja) * | 2012-12-20 | 2017-09-13 | ライオン株式会社 | 高血糖リスク判定用マーカーペプチドおよびその用途 |
| EP3049442A4 (en) | 2013-09-26 | 2017-06-28 | Costim Pharmaceuticals Inc. | Methods for treating hematologic cancers |
| JOP20200094A1 (ar) | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
| JOP20200096A1 (ar) | 2014-01-31 | 2017-06-16 | Children’S Medical Center Corp | جزيئات جسم مضاد لـ tim-3 واستخداماتها |
| CA2936962C (en) | 2014-03-14 | 2024-03-05 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
| CA2960824A1 (en) | 2014-09-13 | 2016-03-17 | Novartis Ag | Combination therapies of alk inhibitors |
| PT3283508T (pt) * | 2015-04-17 | 2021-06-21 | Alpine Immune Sciences Inc | Proteínas imuno modulatórias com afinidades afináveis |
| TWI726920B (zh) * | 2015-10-14 | 2021-05-11 | 耶魯大學 | 基因體規模的ｔ細胞活性陣列、其製造方法、其用於辨識免疫調節因子的方法及其用途 |
| AU2017250358B2 (en) | 2016-04-15 | 2023-06-01 | Alpine Immune Sciences, Inc. | ICOS ligand variant immunomodulatory proteins and uses thereof |
| KR20230091191A (ko) | 2016-05-27 | 2023-06-22 | 아게누스 인코포레이티드 | 항-tim-3 항체 및 이의 사용 방법 |
| SG10201911972QA (en) | 2016-07-14 | 2020-02-27 | Bristol Myers Squibb Co | Antibodies against tim3 and uses thereof |
| EP3970749A1 (en) * | 2016-08-26 | 2022-03-23 | BeiGene, Ltd. | Anti-tim-3 antibodies and use thereof |
| ES2912269T3 (es) | 2016-09-27 | 2022-05-25 | Cero Therapeutics Inc | Moléculas de receptor de engullimiento quimérico |
| WO2018086594A1 (en) | 2016-11-11 | 2018-05-17 | Beijing Biocytogen Co., Ltd | Genetically modified non-human animal with human or chimeric tim-3 |
| EP3725327A3 (en) * | 2017-04-10 | 2021-01-20 | Immatics Biotechnologies GmbH | Peptides and combination thereof for use in the immunotherapy against cancers |
| CA3073421A1 (en) | 2017-09-26 | 2019-04-04 | Daniel Mark COREY | Chimeric engulfment receptor molecules and methods of use |
| CN108037292A (zh) * | 2017-11-29 | 2018-05-15 | 天津市湖滨盘古基因科学发展有限公司 | 一种人的磷脂酰丝氨酸受体突变蛋白及其应用 |
| WO2019191334A1 (en) | 2018-03-28 | 2019-10-03 | Cero Therapeutics, Inc. | Chimeric tim4 receptors and uses thereof |
| JP7444781B2 (ja) | 2018-03-28 | 2024-03-06 | セロ・セラピューティクス・インコーポレイテッド | 細胞免疫療法組成物およびその使用 |
| CN110412263B (zh) * | 2019-07-31 | 2023-01-31 | 中国农业科学院茶叶研究所 | 一种快速高效的茶树质体型谷氨酰胺合成酶基因定位方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6066322A (en) * | 1995-03-03 | 2000-05-23 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of immune disorders |
| ES2258793T5 (es) * | 1996-05-24 | 2010-01-25 | Biogen Idec Ma Inc. | Moduladores de la regeneracion tisular. |
| US5986059A (en) * | 1996-06-14 | 1999-11-16 | Bayer Corporation | T-cell selective interleukin-4 agonists |
| US7060458B1 (en) * | 1997-08-14 | 2006-06-13 | Wyeth | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
| JP2002501738A (ja) * | 1998-01-30 | 2002-01-22 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ６７個のヒト分泌タンパク質 |
| DE69938293T2 (de) * | 1998-03-27 | 2009-03-12 | Bruce J. Beverly Hills Bryan | Luciferase, gfp fluoreszenzproteine, kodierende nukleinsaüre und ihre verwendung in der diagnose |
| WO2002081517A2 (en) | 2001-01-19 | 2002-10-17 | Curagen Corporation | Novel polypeptides and nucleic acids encoded thereby |
| MXPA04000034A (es) * | 2001-06-29 | 2005-11-23 | Univ Leland Stanford Junior | Genes regulatorios de celulas t metodos para utilizar los mismos. |
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- 2002-07-01 JP JP2003509084A patent/JP4572276B2/ja not_active Expired - Fee Related
- 2002-07-01 US US10/188,012 patent/US7553939B2/en not_active Expired - Fee Related
- 2002-07-01 IL IL15962702A patent/IL159627A0/xx unknown
- 2002-07-01 CA CA002452196A patent/CA2452196A1/en not_active Abandoned
- 2002-07-01 EP EP02748027A patent/EP1406653A4/en not_active Withdrawn
- 2002-07-01 CN CNA028130154A patent/CN1538853A/zh active Pending
- 2002-07-01 WO PCT/US2002/020890 patent/WO2003002722A2/en not_active Ceased
- 2002-07-01 NZ NZ530451A patent/NZ530451A/en unknown
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2004
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- 2009-06-16 US US12/485,765 patent/US20090252737A1/en not_active Abandoned
- 2009-10-16 JP JP2009239582A patent/JP2010057492A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003002722A3 (en) | 2003-04-03 |
| NZ530451A (en) | 2008-04-30 |
| JP2007000146A (ja) | 2007-01-11 |
| JP4572276B2 (ja) | 2010-11-04 |
| JP2010057492A (ja) | 2010-03-18 |
| US7553939B2 (en) | 2009-06-30 |
| EP1406653A4 (en) | 2005-05-04 |
| WO2003002722A2 (en) | 2003-01-09 |
| ZA200400013B (en) | 2006-05-31 |
| US20030124114A1 (en) | 2003-07-03 |
| JP4351233B2 (ja) | 2009-10-28 |
| EP1406653A2 (en) | 2004-04-14 |
| US20090252737A1 (en) | 2009-10-08 |
| CA2452196A1 (en) | 2003-01-09 |
| WO2003002722A9 (en) | 2004-04-15 |
| CN1538853A (zh) | 2004-10-20 |
| KR20040014997A (ko) | 2004-02-18 |
| JP2005500039A (ja) | 2005-01-06 |
| IL159627A0 (en) | 2004-06-01 |
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