MXPA03010380A - Uso de inhibidores de la proteasa para el virus de inmunodeficiencia humana (vih) para bloquear la migracion y/o invasion de celulas, infiltracion de tejido y formacion de edema. - Google Patents
Uso de inhibidores de la proteasa para el virus de inmunodeficiencia humana (vih) para bloquear la migracion y/o invasion de celulas, infiltracion de tejido y formacion de edema.Info
- Publication number
- MXPA03010380A MXPA03010380A MXPA03010380A MXPA03010380A MXPA03010380A MX PA03010380 A MXPA03010380 A MX PA03010380A MX PA03010380 A MXPA03010380 A MX PA03010380A MX PA03010380 A MXPA03010380 A MX PA03010380A MX PA03010380 A MXPA03010380 A MX PA03010380A
- Authority
- MX
- Mexico
- Prior art keywords
- hiv
- invasion
- protease
- inhibitors
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
La presente invencion se refiere a un metodo para bloquear la invasion de celulas normales, neoplasticas inflamatorias o inmunes, infiltracion del tejido, y/o formacion de oedema a traves de la inhibicion o modulacion de moleculas y enzimas proteoliticas tales como, pero no exclusivamente, MMPs, para la terapia de todas las enfermedades cuya patogenesis se refiere a los procesos anteriores, incluyendo tumores, enfermedades angioproliferativas no neoplasticas, enfermedades inflamatorias, o enfermedades autoinmunes, el metodo se basa en el uso de loa inhibidores de la proteasa del virus VIH (VIH-PI) .
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001RM000210A ITRM20010210A1 (it) | 2001-04-18 | 2001-04-18 | Uso degli inibitori della proteasi del virus dell'immunodeficienza umana (hiv)nella terapia del sarcoma di kaposi, dei tumori e delle malatt |
PCT/EP2002/004303 WO2002087583A2 (en) | 2001-04-18 | 2002-04-18 | Use of hiv-protease inhibitors to block cell migration and/or invasion, tissue infiltration and oedema formation |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03010380A true MXPA03010380A (es) | 2004-03-16 |
Family
ID=11455472
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03010380A MXPA03010380A (es) | 2001-04-18 | 2002-04-18 | Uso de inhibidores de la proteasa para el virus de inmunodeficiencia humana (vih) para bloquear la migracion y/o invasion de celulas, infiltracion de tejido y formacion de edema. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060088545A1 (es) |
EP (1) | EP1401447A2 (es) |
CN (1) | CN1700916A (es) |
AP (1) | AP2003002901A0 (es) |
BG (1) | BG108368A (es) |
CA (1) | CA2447748A1 (es) |
CZ (1) | CZ20033113A3 (es) |
EA (1) | EA006678B1 (es) |
EE (1) | EE200300507A (es) |
HU (1) | HUP0401199A2 (es) |
IT (1) | ITRM20010210A1 (es) |
MX (1) | MXPA03010380A (es) |
SK (1) | SK14212003A3 (es) |
WO (1) | WO2002087583A2 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002346594A1 (en) * | 2001-12-14 | 2003-06-30 | Cedars-Sinai Medical Center | Use of hiv-1 protease inhibitors and their derivatives in the treatment of inflammation |
US7812034B2 (en) * | 2003-11-04 | 2010-10-12 | City Of Hope | Method of using protease inhibitors for the treatment of liposarcomas |
US20090010990A1 (en) * | 2007-06-20 | 2009-01-08 | Little Marisa A | Process for depositing calcium phosphate therapeutic coatings with controlled release rates and a prosthesis coated via the process |
US8741924B2 (en) | 2010-05-06 | 2014-06-03 | The Feinstein Institute For Medical Research | Compounds and methods for treatment of systemic lupus erythematosus |
CA2822639A1 (en) * | 2010-12-22 | 2012-06-28 | The Feinstein Institute For Medical Research | Methods for treating systemic lupus erythematosus using hiv protease inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2779653B1 (fr) * | 1998-06-11 | 2002-12-20 | Inst Nat Sante Rech Med | Utilisation de composes modulateurs du proteasome en therapie |
AU1930900A (en) * | 1998-12-04 | 2000-06-26 | University Of Maryland Biotechnology Institute | Use of protease inhibitors to modulate cellular pathways, immunity and therapiesassociated therewith |
-
2001
- 2001-04-18 IT IT2001RM000210A patent/ITRM20010210A1/it unknown
-
2002
- 2002-04-18 EE EEP200300507A patent/EE200300507A/xx unknown
- 2002-04-18 US US10/549,958 patent/US20060088545A1/en not_active Abandoned
- 2002-04-18 EA EA200301130A patent/EA006678B1/ru not_active IP Right Cessation
- 2002-04-18 WO PCT/EP2002/004303 patent/WO2002087583A2/en not_active Application Discontinuation
- 2002-04-18 SK SK1421-2003A patent/SK14212003A3/sk unknown
- 2002-04-18 AP APAP/P/2003/002901A patent/AP2003002901A0/en unknown
- 2002-04-18 CA CA002447748A patent/CA2447748A1/en not_active Abandoned
- 2002-04-18 MX MXPA03010380A patent/MXPA03010380A/es not_active Application Discontinuation
- 2002-04-18 EP EP02766632A patent/EP1401447A2/en not_active Ceased
- 2002-04-18 CZ CZ20033113A patent/CZ20033113A3/cs unknown
- 2002-04-18 CN CNA028121260A patent/CN1700916A/zh active Pending
- 2002-04-18 HU HU0401199A patent/HUP0401199A2/hu unknown
-
2003
- 2003-11-18 BG BG108368A patent/BG108368A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
SK14212003A3 (sk) | 2004-06-08 |
BG108368A (bg) | 2005-01-31 |
ITRM20010210A0 (it) | 2001-04-18 |
ITRM20010210A1 (it) | 2002-10-18 |
HUP0401199A2 (hu) | 2004-12-28 |
EP1401447A2 (en) | 2004-03-31 |
CA2447748A1 (en) | 2002-11-07 |
US20060088545A1 (en) | 2006-04-27 |
AP2003002901A0 (en) | 2003-12-31 |
CZ20033113A3 (cs) | 2004-07-14 |
CN1700916A (zh) | 2005-11-23 |
WO2002087583A3 (en) | 2002-12-19 |
EE200300507A (et) | 2004-02-16 |
EA006678B1 (ru) | 2006-02-24 |
EA200301130A1 (ru) | 2004-04-29 |
WO2002087583A2 (en) | 2002-11-07 |
WO2002087583B1 (en) | 2003-11-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |