DK1096951T3 - Anvendelse af bromelainproteaser til inhiberingen af blodkoaguleringen - Google Patents

Anvendelse af bromelainproteaser til inhiberingen af blodkoaguleringen

Info

Publication number
DK1096951T3
DK1096951T3 DK98942559T DK98942559T DK1096951T3 DK 1096951 T3 DK1096951 T3 DK 1096951T3 DK 98942559 T DK98942559 T DK 98942559T DK 98942559 T DK98942559 T DK 98942559T DK 1096951 T3 DK1096951 T3 DK 1096951T3
Authority
DK
Denmark
Prior art keywords
proteases
blood coagulation
inhibition
inhibiting
bromelaine
Prior art date
Application number
DK98942559T
Other languages
English (en)
Inventor
Rainer Maurer
Klaus Eckert
Edyta Grabowska
Klaus Eschmann
Original Assignee
Ursapharm Arzneimittel Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ursapharm Arzneimittel Gmbh filed Critical Ursapharm Arzneimittel Gmbh
Application granted granted Critical
Publication of DK1096951T3 publication Critical patent/DK1096951T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98942559T 1998-07-15 1998-07-15 Anvendelse af bromelainproteaser til inhiberingen af blodkoaguleringen DK1096951T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1998/004406 WO2000003729A1 (de) 1998-07-15 1998-07-15 Verwendung von bromelainproteasen zur hemmung der blutgerinnung

Publications (1)

Publication Number Publication Date
DK1096951T3 true DK1096951T3 (da) 2002-10-21

Family

ID=8167005

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98942559T DK1096951T3 (da) 1998-07-15 1998-07-15 Anvendelse af bromelainproteaser til inhiberingen af blodkoaguleringen

Country Status (10)

Country Link
US (1) US6803038B1 (da)
EP (1) EP1096951B1 (da)
AT (1) ATE222121T1 (da)
AU (1) AU9066198A (da)
CA (1) CA2333252C (da)
DE (1) DE59805215D1 (da)
DK (1) DK1096951T3 (da)
ES (1) ES2182356T3 (da)
PT (1) PT1096951E (da)
WO (1) WO2000003729A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165334A0 (en) * 2004-11-22 2006-01-15 Mediwound Ltd Debriding composition from bromelain and methods of producing same
EP2036978A1 (en) * 2007-09-14 2009-03-18 URSAPHARM Arzneimittel GmbH & Co. KG Recombinant preparation of selected bromelain fractions
DE102008062136B4 (de) * 2008-12-16 2012-05-03 Kamamed Ug Pharmazeutische Zusammensetzung auf Basis von Peptid aus Kamelmilch
ES2909565T3 (es) 2016-01-31 2022-05-09 Mediwound Ltd Composición desbridante para el tratamiento de heridas

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63295515A (ja) * 1987-05-26 1988-12-01 Kao Corp 腸溶性抗血液凝固・血栓溶解製剤
DE4130221C2 (de) 1991-09-11 1997-08-07 Mucos Pharma Gmbh Verwendung von proteolytischen Enzymen zur Herstellung eines Medikaments zur Behandlung von Autoimmun-Krankheiten, an deren Entstehung Proteine mit einer C¶H¶2-Domäne beteiligt sind
SG42846A1 (en) * 1992-06-30 1997-10-17 Cortecs Ltd Use of enzymes especially bromelain in the treatment of diarrhoea
DE4302060A1 (de) 1993-01-26 1994-07-28 Mucos Pharma Gmbh & Co Verwendung von Bromelain zur Krebstherapie und/oder Metastasen-Prophylaxe
GB9313188D0 (en) * 1993-06-25 1993-08-11 Cortecs Ltd Medical use of enzymes
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
JP2001513636A (ja) * 1997-02-25 2001-09-04 コルテクス(ユーケイ)リミティッド ブロメラインの成分
EP1865055B1 (en) * 1997-02-25 2012-12-05 Sarantis Pty Ltd Component of bromelain

Also Published As

Publication number Publication date
WO2000003729A1 (de) 2000-01-27
EP1096951B1 (de) 2002-08-14
DE59805215D1 (de) 2002-09-19
US6803038B1 (en) 2004-10-12
ATE222121T1 (de) 2002-08-15
EP1096951A1 (de) 2001-05-09
ES2182356T3 (es) 2003-03-01
AU9066198A (en) 2000-02-07
CA2333252C (en) 2008-11-25
CA2333252A1 (en) 2000-01-27
PT1096951E (pt) 2003-01-31

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