MXPA03007037A - Ligandos del antigeno de membrana especifico de prostata (amep) y usos relacionados del mismo. - Google Patents
Ligandos del antigeno de membrana especifico de prostata (amep) y usos relacionados del mismo.Info
- Publication number
- MXPA03007037A MXPA03007037A MXPA03007037A MXPA03007037A MXPA03007037A MX PA03007037 A MXPA03007037 A MX PA03007037A MX PA03007037 A MXPA03007037 A MX PA03007037A MX PA03007037 A MXPA03007037 A MX PA03007037A MX PA03007037 A MXPA03007037 A MX PA03007037A
- Authority
- MX
- Mexico
- Prior art keywords
- psma ligands
- uses related
- modified psma
- diagnosis
- detection
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 2
- 102100041003 Glutamate carboxypeptidase 2 Human genes 0.000 abstract 2
- 101000892862 Homo sapiens Glutamate carboxypeptidase 2 Proteins 0.000 abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229920001481 poly(stearyl methacrylate) Polymers 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/005—Compounds of elements of Group 5 of the Periodic Table without metal-carbon linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/32—Esters thereof
- C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6596—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having atoms other than oxygen, sulfur, selenium, tellurium, nitrogen or phosphorus as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/72—Aliphatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
- Pregnancy & Childbirth (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26705501P | 2001-02-07 | 2001-02-07 | |
PCT/US2002/021996 WO2002098885A1 (en) | 2001-02-07 | 2002-02-07 | Modified psma ligands and uses related thereto |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03007037A true MXPA03007037A (es) | 2003-11-18 |
Family
ID=23017130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03007037A MXPA03007037A (es) | 2001-02-07 | 2002-02-07 | Ligandos del antigeno de membrana especifico de prostata (amep) y usos relacionados del mismo. |
Country Status (8)
Country | Link |
---|---|
US (4) | US6875886B2 (es) |
EP (1) | EP1363920B1 (es) |
JP (1) | JP2005507857A (es) |
AT (1) | ATE337011T1 (es) |
CA (1) | CA2436408A1 (es) |
DE (1) | DE60214134T2 (es) |
MX (1) | MXPA03007037A (es) |
WO (1) | WO2002098885A1 (es) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002239403A1 (en) | 2000-12-01 | 2002-06-11 | The Johns Hopkins University | Tissue specific prodrugs |
DE60323677D1 (de) * | 2003-01-10 | 2008-10-30 | Millennium Pharm Inc | Verfahren zur bestimmung des wiederauftretens von prostata krebs |
WO2007001448A2 (en) | 2004-11-04 | 2007-01-04 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
US20090098046A1 (en) * | 2005-01-14 | 2009-04-16 | Michael Becker | Combination Cancer Therapy with Anti-PSMA Antibodies |
JP2008535865A (ja) * | 2005-04-08 | 2008-09-04 | サイトジェン コーポレーション | 抗psmaコンジュゲート抗体 |
US20060264414A1 (en) * | 2005-04-08 | 2006-11-23 | The Board of Regents, University and Community College System of Nevada on behalf of the | Fluorous 2,2'-bipyridines and fluorinated biphasic sysems for ligand design |
US20090027280A1 (en) * | 2005-05-05 | 2009-01-29 | Frangioni John V | Micro-scale resonant devices and methods of use |
CA3000520C (en) | 2005-08-24 | 2023-04-04 | Immunogen, Inc. | Process for preparing antibody maytansinoid conjugates |
AU2006310177A1 (en) * | 2005-10-18 | 2007-05-10 | Centre National De La Recherche Scientifique (Cnrs) | Hypophosphorous acid derivatives and their therapeutical applications |
WO2007070682A2 (en) | 2005-12-15 | 2007-06-21 | Massachusetts Institute Of Technology | System for screening particles |
US7696185B2 (en) * | 2006-03-14 | 2010-04-13 | Cancer Targered Technology LLC | Peptidomimetic inhibitors of PSMA, compounds comprising them, and methods of use |
JP2009534309A (ja) | 2006-03-31 | 2009-09-24 | マサチューセッツ インスティテュート オブ テクノロジー | 治療剤の標的化送達のためのシステム |
US9381477B2 (en) * | 2006-06-23 | 2016-07-05 | Massachusetts Institute Of Technology | Microfluidic synthesis of organic nanoparticles |
WO2008006006A1 (en) | 2006-07-03 | 2008-01-10 | Beth Israel Deaconess Medical Center, Inc. | Histology methods |
US20100144845A1 (en) * | 2006-08-04 | 2010-06-10 | Massachusetts Institute Of Technology | Oligonucleotide systems for targeted intracellular delivery |
WO2008027995A2 (en) * | 2006-08-29 | 2008-03-06 | Beth Israel Deaconess Medical Center, Inc. | Radio-labeled materials and methods of making and using the same |
EP2087337A4 (en) * | 2006-11-03 | 2010-09-08 | Purdue Research Foundation | METHOD AND DEVICE FOR EX-VIVO FLOW CYTOMETRY |
EP2134830A2 (en) | 2007-02-09 | 2009-12-23 | Massachusetts Institute of Technology | Oscillating cell culture bioreactor |
EP2144600A4 (en) * | 2007-04-04 | 2011-03-16 | Massachusetts Inst Technology | POLY (AMINIC ACID) TARGET MOLECULES |
AU2008269094B2 (en) | 2007-06-26 | 2015-04-09 | The Johns Hopkins University | Labeled inhibitors of prostate specific membrane antigen (PSMA), biological evaluation, and use as imaging agents |
US20100137258A1 (en) * | 2007-08-01 | 2010-06-03 | Francine Acher | Thiophosphi(o)nic acid derivatives and their therapeutical applications |
EP3388086B1 (en) | 2007-08-17 | 2020-10-07 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
FR2920086A1 (fr) | 2007-08-24 | 2009-02-27 | Univ Grenoble 1 | Systeme et procede d'analyse pour une operation chirurgicale par endoscopie |
PL2644192T3 (pl) | 2007-09-28 | 2017-09-29 | Pfizer Inc. | Ukierunkowanie na komórki nowotworowe z zastosowaniem nanocząstek |
CN101861165A (zh) | 2007-10-12 | 2010-10-13 | 麻省理工学院 | 疫苗纳米技术 |
WO2010005726A2 (en) | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
EA021422B1 (ru) | 2008-06-16 | 2015-06-30 | Бинд Терапьютикс, Инк. | Полимерные наночастицы, содержащие терапевтическое средство, и способ их получения |
ES2721850T3 (es) * | 2008-06-16 | 2019-08-05 | Pfizer | Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas |
US8277812B2 (en) | 2008-10-12 | 2012-10-02 | Massachusetts Institute Of Technology | Immunonanotherapeutics that provide IgG humoral response without T-cell antigen |
US8591905B2 (en) | 2008-10-12 | 2013-11-26 | The Brigham And Women's Hospital, Inc. | Nicotine immunonanotherapeutics |
WO2010045598A2 (en) * | 2008-10-17 | 2010-04-22 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
WO2010068866A2 (en) | 2008-12-12 | 2010-06-17 | Bind Biosciences | Therapeutic particles suitable for parenteral administration and methods of making and using same |
ES2776126T3 (es) | 2008-12-15 | 2020-07-29 | Pfizer | Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos |
US10493169B2 (en) | 2009-02-06 | 2019-12-03 | Beth Israel Deaconess Medical Center | Use of charge-balanced imaging agents for determining renal function |
SG2014009146A (en) | 2009-02-06 | 2014-05-29 | Beth Israel Hospital | Charge-balanced imaging agents |
CA2769444A1 (en) | 2009-05-19 | 2010-11-25 | Aic Blab Company | Composite current collector and methods therefor |
JP5784592B2 (ja) | 2009-06-03 | 2015-09-24 | イミュノジェン・インコーポレーテッド | 抱合方法 |
CN102811743B (zh) | 2009-12-11 | 2015-11-25 | 佰恩德治疗股份有限公司 | 冻干治疗颗粒的稳定制剂 |
US9295649B2 (en) | 2009-12-15 | 2016-03-29 | Bind Therapeutics, Inc. | Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers |
US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
EP2691155B1 (en) | 2011-03-29 | 2018-11-14 | Immunogen, Inc. | Preparation of maytansinoid antibody conjugates by a one-step process |
JP6501524B2 (ja) * | 2012-02-24 | 2019-04-17 | コーネル ユニヴァーシティー | Psma上昇により致死性前立腺癌が同定される |
JP2015508903A (ja) * | 2012-02-28 | 2015-03-23 | コーネル ユニヴァーシティー | 前立腺癌におけるアンドロゲン活性のバイオマーカーとしてのpsma |
NZ705812A (en) | 2012-09-17 | 2018-08-31 | Pfizer | Process for preparing therapeutic nanoparticles |
AU2013326881B2 (en) | 2012-10-04 | 2018-08-02 | Immunogen, Inc. | Use of a PVDF membrane to purify cell-binding agent cytotoxic agent conjugates |
KR102318999B1 (ko) | 2012-11-15 | 2021-10-29 | 엔도사이트, 인코포레이티드 | Psma 발현 세포에 의해 야기되는 질병을 치료하기 위한 컨쥬게이트 |
JP6192799B2 (ja) | 2013-03-15 | 2017-09-06 | パーデュー・リサーチ・ファウンデーションPurdue Research Foundation | 腫瘍の標的画像化に使用される化合物にコンジュゲートしているアミノ酸連結基の合成および組成物 |
EP2842578B1 (en) * | 2013-08-27 | 2018-06-27 | GILUPI GmbH | Diagnostic device for the detection of biomarkers |
KR102282378B1 (ko) | 2013-10-18 | 2021-07-27 | 도이체스 크렙스포르슝스첸트룸 | 전립선 특이적 막 항원(psma)의 표지된 억제제, 조영제로서의 이의 용도 및 전립선암 치료용 약제 |
EP3116547B1 (en) | 2014-03-14 | 2019-06-05 | Pfizer Inc | Therapeutic nanoparticles comprising a therapeutic agent and methods of making and using same |
WO2016040179A1 (en) * | 2014-09-08 | 2016-03-17 | Molecular Insight Pharmaceuticals, Inc. | Organ protection in psma-targeted radionuclide therapy of prostate cancer |
US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
DE102019215585B4 (de) * | 2019-10-10 | 2022-02-17 | KCM Egészségügyi és Tudományos Korlátolt Felelösségü Társaság | Verfahren zur prävention von strahlenschäden in humanen drüsen |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009820A1 (en) | 1992-11-05 | 1994-05-11 | Sloan-Kettering Institute For Cancer Research | Prostate-specific membrane antigen |
US5804602A (en) * | 1996-06-17 | 1998-09-08 | Guilford Pharmaceuticals Inc. | Methods of cancer treatment using naaladase inhibitors |
US6071965A (en) * | 1996-06-17 | 2000-06-06 | Guilford Pharmaceuticals Inc. | Phosphinic alkanoic acid derivatives |
KR20000016750A (ko) | 1996-06-17 | 2000-03-25 | 토마스 씨. 서 | Naaladase 억제를 이용한 암의 치료방법. |
US6054444A (en) | 1997-04-24 | 2000-04-25 | Guilford Pharmaceuticals Inc. | Phosphonic acid derivatives |
US6046180A (en) | 1996-06-17 | 2000-04-04 | Guilford Pharmaceuticals Inc. | NAALADase inhibitors |
US6025345A (en) * | 1996-06-17 | 2000-02-15 | Guilford Pharmaceuticals Inc. | Inhibitors of NAALADase enzyme activity |
US5902817A (en) | 1997-04-09 | 1999-05-11 | Guilford Pharmaceuticals Inc. | Certain sulfoxide and sulfone derivatives |
US6384022B1 (en) * | 1996-06-17 | 2002-05-07 | Guilford Pharmaceuticals Inc. | Prodrugs of NAALAdase inhibitors |
US6025344A (en) | 1996-06-17 | 2000-02-15 | Guilford Pharmaceuticals Inc. | Certain dioic acid derivatives useful as NAALADase inhibitors |
US5962521A (en) | 1997-04-04 | 1999-10-05 | Guilford Pharmaceuticals Inc. | Hydroxamic acid derivatives |
TR199901173T2 (xx) | 1996-09-27 | 1999-07-21 | Guilford Pharmaceuticals, Inc. | Canl�larda glutamat anormalli�inin tedavisi ve n�ronal aktivitenin d�zenlenmesi i�in y�ntemler ve NAALADase bile�imleri. |
US5981209A (en) | 1997-12-04 | 1999-11-09 | Guilford Pharmaceuticals Inc. | Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia |
US6444657B1 (en) * | 1998-12-31 | 2002-09-03 | Guilford Pharmaceuticals Inc. | Methods for treating certain diseases using naaladase inhibitors |
US6348464B1 (en) | 1999-11-12 | 2002-02-19 | Guilford Pharmaceuticals, Inc. | Pyrrolecarbonylimino derivatives as naaladase inhibitors |
US7254409B2 (en) * | 2000-04-14 | 2007-08-07 | Ntt Docomo, Inc. | Multicast service providing system, multicast service providing method, information distributor, radio terminal, and radio base station |
WO2001092273A2 (en) | 2000-05-30 | 2001-12-06 | Guilford Pharmaceuticals Inc. | Benzenedicarboxylic acid derivatives |
US6684076B2 (en) * | 2000-08-14 | 2004-01-27 | Vesuvius Inc. | Communique system with hierarchical communique coverage areas in cellular communication networks |
US6907023B2 (en) * | 2000-08-14 | 2005-06-14 | Vesuvius, Inc. | Communique system with dynamic bandwidth allocation in cellular communication networks |
US6687498B2 (en) * | 2000-08-14 | 2004-02-03 | Vesuvius Inc. | Communique system with noncontiguous communique coverage areas in cellular communication networks |
US6954641B2 (en) * | 2000-08-14 | 2005-10-11 | Vesivius, Inc. | Communique wireless subscriber device for a cellular communication network |
US7024200B2 (en) * | 2000-08-14 | 2006-04-04 | Vesuvius, Inc. | Communique system with active feedback for cellular communication networks |
US6829486B2 (en) * | 2000-08-14 | 2004-12-07 | Vesuvius | Communique system for combined cellular and wireline communication networks |
US6741856B2 (en) * | 2000-08-14 | 2004-05-25 | Vesuvius Inc. | Communique system for virtual private narrowcasts in cellular communication networks |
US6681115B1 (en) * | 2000-08-14 | 2004-01-20 | Vesuvius Inc. | Communique subscriber handoff between a narrowcast cellular communication network and a point-to-point cellular communication network |
US6594498B1 (en) * | 2000-08-14 | 2003-07-15 | Vesuvius, Inc. | Communique system for cellular communication networks |
EP1341557A2 (en) * | 2000-10-27 | 2003-09-10 | Beth Israel Deaconess Medical Center | Non-isotopic detection of osteoblastic activity in vivo using modified bisphosphonates |
MXPA03006467A (es) | 2001-01-17 | 2004-01-29 | Guilford Pharm Inc | Inibidores de naaladasa a base de tiol. |
-
2002
- 2002-02-07 AT AT02761082T patent/ATE337011T1/de not_active IP Right Cessation
- 2002-02-07 JP JP2003502006A patent/JP2005507857A/ja active Pending
- 2002-02-07 MX MXPA03007037A patent/MXPA03007037A/es unknown
- 2002-02-07 DE DE60214134T patent/DE60214134T2/de not_active Expired - Fee Related
- 2002-02-07 CA CA002436408A patent/CA2436408A1/en not_active Abandoned
- 2002-02-07 WO PCT/US2002/021996 patent/WO2002098885A1/en active IP Right Grant
- 2002-02-07 EP EP02761082A patent/EP1363920B1/en not_active Expired - Lifetime
- 2002-02-07 US US10/071,890 patent/US6875886B2/en not_active Expired - Lifetime
-
2004
- 2004-06-16 US US10/869,790 patent/US20040229845A1/en not_active Abandoned
-
2005
- 2005-07-01 US US11/173,055 patent/US20050245486A1/en not_active Abandoned
-
2007
- 2007-07-19 US US11/880,124 patent/US20080175789A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ATE337011T1 (de) | 2006-09-15 |
EP1363920A4 (en) | 2004-04-21 |
EP1363920A1 (en) | 2003-11-26 |
DE60214134D1 (de) | 2006-10-05 |
JP2005507857A (ja) | 2005-03-24 |
DE60214134T2 (de) | 2007-07-19 |
US20050245486A1 (en) | 2005-11-03 |
US20040229845A1 (en) | 2004-11-18 |
CA2436408A1 (en) | 2002-12-12 |
US20080175789A1 (en) | 2008-07-24 |
WO2002098885A1 (en) | 2002-12-12 |
US20040110723A1 (en) | 2004-06-10 |
EP1363920B1 (en) | 2006-08-23 |
US6875886B2 (en) | 2005-04-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA03007037A (es) | Ligandos del antigeno de membrana especifico de prostata (amep) y usos relacionados del mismo. | |
WO2003048301A3 (en) | Anti-hla-dr antibodies and the methods of using thereof | |
WO2000028090A3 (en) | Diagnostic assay for cancer | |
MXPA03003151A (es) | Metodos de diagnostico de cancer de prostata, composiciones y metodos para seleccionar moduladores de cancer de prostata. | |
WO2004067570A3 (en) | Prostate cancer diagnosis and treatment | |
WO2001031580A3 (en) | Methods and devices for identifying patterns in biological systems | |
WO2005031001A3 (en) | Novel therapeutic targets in cancer | |
ATE489108T1 (de) | Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie | |
WO2004060302A3 (en) | Methods and compositions for the diagnosis, prognosis, and treatment of cancer | |
WO2001073030A3 (en) | Compositions and methods of diagnosing, monitoring, staging, imaging and treating colon cancer | |
WO2003046581A3 (en) | Methods for diagnosis and treatment of epithelial-derived cancers,such as colorectal cancers and kidney cancers | |
WO2004060304A3 (en) | Novel compositions and methods in cancer | |
WO2004058146A3 (en) | Novel compositions and methods in cancer | |
WO2007033167A3 (en) | Compositions and methods for detecting and treating cancer | |
AU4927501A (en) | Prostate cancer markers | |
WO2003033731A3 (en) | Methods for detecting ovarian cancer | |
WO2002010436A3 (en) | Prognostic classification of breast cancer | |
WO2001031579A3 (en) | Methods and devices for identifying patterns in biological patterns | |
AU8727201A (en) | Genes involved in intestinal inflammatory diseases and use thereof | |
WO2005053604A3 (en) | Antibodies specific for cancer associated antigen sm5-1 and uses thereof | |
WO1997029199A3 (en) | Prostate specific antigen peptides and uses thereof | |
WO2005070456A3 (en) | Diagnosing and treating female reproductive tract or chilhood cancer with pmsa antibodies | |
WO2008104805A3 (en) | Proteins | |
EP1064005A4 (en) | USE OF THE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR AS A TARGET IN THE DIAGNOSIS OF METASTASES | |
TW200517122A (en) | Antibodies specific for cancer associated antigen SM5-1 and uses thereof |