MXPA03000194A - Formulaciones de arginina de liberacion controlada. - Google Patents
Formulaciones de arginina de liberacion controlada.Info
- Publication number
- MXPA03000194A MXPA03000194A MXPA03000194A MXPA03000194A MXPA03000194A MX PA03000194 A MXPA03000194 A MX PA03000194A MX PA03000194 A MXPA03000194 A MX PA03000194A MX PA03000194 A MXPA03000194 A MX PA03000194A MX PA03000194 A MXPA03000194 A MX PA03000194A
- Authority
- MX
- Mexico
- Prior art keywords
- controlled release
- arginine formulations
- arginine
- release arginine
- formulations
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000004475 Arginine Substances 0.000 title 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 3
- 229930064664 L-arginine Natural products 0.000 abstract 3
- 235000014852 L-arginine Nutrition 0.000 abstract 3
- 230000036983 biotransformation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Se describe en la presente una formulacion de liberacion sostenida de L-arginina sola o en combinacion con un agente que aumenta la biotransformacion de L-arginina en NO. La figura 1A muestra una representacion esquematica de trayectorias independientes y dependientes de L-arginina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60559900A | 2000-06-28 | 2000-06-28 | |
PCT/US2001/020887 WO2002000212A1 (en) | 2000-06-28 | 2001-06-28 | Controlled release arginine formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03000194A true MXPA03000194A (es) | 2004-09-13 |
Family
ID=24424380
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03000194A MXPA03000194A (es) | 2000-06-28 | 2001-06-28 | Formulaciones de arginina de liberacion controlada. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1377284B1 (es) |
JP (1) | JP2004513877A (es) |
AT (1) | ATE417609T1 (es) |
AU (1) | AU2001271700A1 (es) |
CA (1) | CA2413816A1 (es) |
DE (1) | DE60137082D1 (es) |
MX (1) | MXPA03000194A (es) |
WO (1) | WO2002000212A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002539257A (ja) | 1999-03-19 | 2002-11-19 | イーノス・ファーマシューティカルス・インコーポレーテッド | 薬剤の脳内生物学的利用率の増加 |
CN1649569B (zh) * | 2002-03-04 | 2010-05-05 | 特瓦制药工业有限公司 | 控释剂型 |
JP2007521324A (ja) * | 2003-09-29 | 2007-08-02 | エノス ファーマシューティカルズ, インク. | 徐放性l−アルギニン調合物並びにその製造法及び使用法 |
JP2010270111A (ja) * | 2009-04-21 | 2010-12-02 | Taisho Pharmaceutical Co Ltd | アルギニン含有錠剤 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2827287B2 (ja) * | 1988-07-05 | 1998-11-25 | 武田薬品工業株式会社 | 水溶性薬物含有徐放型マイクロカプセル |
WO1990011070A1 (en) * | 1989-03-17 | 1990-10-04 | Pitman-Moore, Inc. | Controlled release delivery device for macromolecular proteins |
US5824331A (en) * | 1992-02-24 | 1998-10-20 | Encelle, Inc. | Bioartificial devices and cellular matrices therefor |
US5968983A (en) * | 1994-10-05 | 1999-10-19 | Nitrosystems, Inc | Method and formulation for treating vascular disease |
US20020068365A1 (en) * | 1998-07-28 | 2002-06-06 | Eric H. Kuhrts | Controlled release nitric oxide producing agents |
JP2002539257A (ja) * | 1999-03-19 | 2002-11-19 | イーノス・ファーマシューティカルス・インコーポレーテッド | 薬剤の脳内生物学的利用率の増加 |
AU1800801A (en) * | 1999-11-17 | 2001-05-30 | Eric H. Kuhrts | Exercise and muscle enhancement formulations |
-
2001
- 2001-06-28 CA CA002413816A patent/CA2413816A1/en not_active Abandoned
- 2001-06-28 JP JP2002504994A patent/JP2004513877A/ja active Pending
- 2001-06-28 WO PCT/US2001/020887 patent/WO2002000212A1/en active Application Filing
- 2001-06-28 DE DE60137082T patent/DE60137082D1/de not_active Expired - Fee Related
- 2001-06-28 AU AU2001271700A patent/AU2001271700A1/en not_active Abandoned
- 2001-06-28 MX MXPA03000194A patent/MXPA03000194A/es not_active Application Discontinuation
- 2001-06-28 AT AT01950733T patent/ATE417609T1/de not_active IP Right Cessation
- 2001-06-28 EP EP01950733A patent/EP1377284B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2002000212A1 (en) | 2002-01-03 |
ATE417609T1 (de) | 2009-01-15 |
EP1377284A1 (en) | 2004-01-07 |
JP2004513877A (ja) | 2004-05-13 |
CA2413816A1 (en) | 2002-01-03 |
EP1377284A4 (en) | 2006-04-12 |
DE60137082D1 (de) | 2009-01-29 |
EP1377284B1 (en) | 2008-12-17 |
AU2001271700A1 (en) | 2002-01-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |