MXPA02012320A - Uso de un agente para suprimir la infeccion y proliferacion del virus del sindrome de inmunodeficiencia humana. - Google Patents
Uso de un agente para suprimir la infeccion y proliferacion del virus del sindrome de inmunodeficiencia humana.Info
- Publication number
- MXPA02012320A MXPA02012320A MXPA02012320A MXPA02012320A MXPA02012320A MX PA02012320 A MXPA02012320 A MX PA02012320A MX PA02012320 A MXPA02012320 A MX PA02012320A MX PA02012320 A MXPA02012320 A MX PA02012320A MX PA02012320 A MXPA02012320 A MX PA02012320A
- Authority
- MX
- Mexico
- Prior art keywords
- proliferation
- agent
- human immunodeficiency
- immunodeficiency syndrome
- syndrome virus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
Abstract
La presente invencion se refiere a agentes para suprimir infeccion y proliferacion del virus de sindrome de inmunodeficiencia humano (VIH-1), que infecta celulas inmunocompetentes tales como macrofagos o celulas dendriticas y provoca la destruccion del sistema inmunologico, y al uso de compuestos conocidos, derivados de macrolidos para la supresion de la infeccion y proliferacion de virus de sindrome de inmunodeficiencia humana en macrofagos de tipo M derivados de monocitos humanos. La presente invencion es util para el tratamiento de pacientes con infeccion por VIH-1 por agentes quimioterapeuticos de bajo costo, y ademas, se utiliza clinicamente como agente suplementario en HAART.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002061788 | 2002-03-07 | ||
| JP2002261024A JP2003327536A (ja) | 2002-03-07 | 2002-09-06 | ヒト免疫不全症候群ウイルスの感染、増殖抑制剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02012320A true MXPA02012320A (es) | 2004-12-13 |
Family
ID=28043681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02012320A MXPA02012320A (es) | 2002-03-07 | 2002-12-13 | Uso de un agente para suprimir la infeccion y proliferacion del virus del sindrome de inmunodeficiencia humana. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7034005B2 (es) |
| EP (1) | EP1350510B1 (es) |
| JP (1) | JP2003327536A (es) |
| KR (1) | KR20030074097A (es) |
| CN (1) | CN1183915C (es) |
| AT (1) | ATE295729T1 (es) |
| AU (1) | AU2002302115B2 (es) |
| CA (1) | CA2412065A1 (es) |
| DE (1) | DE60204211T2 (es) |
| DK (1) | DK1350510T3 (es) |
| ES (1) | ES2241967T3 (es) |
| HK (1) | HK1056838A1 (es) |
| MX (1) | MXPA02012320A (es) |
| PT (1) | PT1350510E (es) |
| RU (1) | RU2250770C2 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1911836A1 (en) * | 2006-10-12 | 2008-04-16 | AVIR Green Hills Biotechnology Trading GmbH | Medium supplement for virus production |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| WO2012021964A1 (en) * | 2010-08-18 | 2012-02-23 | UNIVERSITé LAVAL | Compounds and therapeutic applications related to inhibition of dendritic cell immunoreceptor (dcir) activity and signaling events |
| CN107074944A (zh) | 2014-09-16 | 2017-08-18 | 美国联合生物医学公司 | 藉由针对cd4之单克隆抗体介导竞争型hiv进入抑制之hiv感染的治疗和功能性治愈 |
| RU2019106804A (ru) | 2016-08-13 | 2020-09-21 | Юнайтед Байофарма, Инк. | Лечение и устойчивая вирусологическая ремиссия при вич-инфекции у haart-стабилизированных пациентов с помощью антител против cd4 |
| CN110709408B (zh) * | 2017-02-22 | 2022-10-25 | Isr免疫系统调节控股公共有限公司 | 新型免疫刺激大环内酯 |
| CN110741011A (zh) * | 2017-02-22 | 2020-01-31 | 免疫系统调节控股有限公司 | 新型免疫刺激大环内酯 |
| EP3585795B1 (en) | 2017-02-22 | 2021-06-09 | ISR Immune System Regulation Holding AB (publ) | Novel immune stimulating macrolides |
| US11059846B2 (en) | 2017-02-22 | 2021-07-13 | ISR Immune System Regulation Holding AB (publ) | Immune stimulating compound |
| WO2019180265A1 (en) | 2018-03-23 | 2019-09-26 | Immune System Regulation Holding Ab | Combinations of macrolide compounds and immune checkpoint inhibitors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0254534A3 (en) | 1986-07-24 | 1991-04-17 | William S. Robinson | Erythromycin derivatives and compositions and use for inhibiting virus replication and disease |
| US5106961A (en) * | 1987-05-26 | 1992-04-21 | Eli Lilly And Company | Erythromycin ring-contracted derivatives |
| US5312837A (en) * | 1991-01-29 | 1994-05-17 | Genelabs Technologies, Inc. | Method of treating viral infections with aryl macrocyclic compounds |
| US5541193A (en) | 1991-09-05 | 1996-07-30 | Abbott Laboratories | Heterocycle-containing macrocyclic immunomodulators |
| FR2683723B1 (fr) | 1991-11-14 | 1995-05-19 | Mayoly Spindler Laboratoires | Nouveaux medicaments antiviraux actifs sur le virus vih. |
| US5545734A (en) | 1994-10-25 | 1996-08-13 | Merck & Co., Inc. | Aryl and heteroaryl macrolides having immunosuppressive activity |
| US6107327A (en) * | 1996-08-30 | 2000-08-22 | Eli Lilly And Company | Therapeutic treatment for HIV infection |
| AU749623B2 (en) | 1998-03-26 | 2002-06-27 | Astellas Pharma Inc. | Sustained release preparations |
-
2002
- 2002-09-06 JP JP2002261024A patent/JP2003327536A/ja active Pending
- 2002-11-15 US US10/294,587 patent/US7034005B2/en not_active Expired - Fee Related
- 2002-11-18 CA CA002412065A patent/CA2412065A1/en not_active Abandoned
- 2002-11-20 RU RU2002131253/15A patent/RU2250770C2/ru not_active IP Right Cessation
- 2002-11-21 AU AU2002302115A patent/AU2002302115B2/en not_active Ceased
- 2002-11-21 KR KR1020020072632A patent/KR20030074097A/ko not_active Application Discontinuation
- 2002-11-25 DK DK02258095T patent/DK1350510T3/da active
- 2002-11-25 ES ES02258095T patent/ES2241967T3/es not_active Expired - Lifetime
- 2002-11-25 DE DE60204211T patent/DE60204211T2/de not_active Expired - Fee Related
- 2002-11-25 EP EP02258095A patent/EP1350510B1/en not_active Expired - Lifetime
- 2002-11-25 AT AT02258095T patent/ATE295729T1/de not_active IP Right Cessation
- 2002-11-25 PT PT02258095T patent/PT1350510E/pt unknown
- 2002-12-11 CN CNB021559244A patent/CN1183915C/zh not_active Expired - Fee Related
- 2002-12-13 MX MXPA02012320A patent/MXPA02012320A/es active IP Right Grant
-
2003
- 2003-12-10 HK HK03108943A patent/HK1056838A1/xx not_active IP Right Cessation
-
2005
- 2005-09-23 US US11/232,930 patent/US20060025357A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20030186900A1 (en) | 2003-10-02 |
| PT1350510E (pt) | 2005-09-30 |
| AU2002302115A1 (en) | 2003-09-25 |
| CN1443538A (zh) | 2003-09-24 |
| ES2241967T3 (es) | 2005-11-01 |
| EP1350510A1 (en) | 2003-10-08 |
| CA2412065A1 (en) | 2003-09-07 |
| DE60204211D1 (de) | 2005-06-23 |
| ATE295729T1 (de) | 2005-06-15 |
| AU2002302115B2 (en) | 2004-11-04 |
| RU2250770C2 (ru) | 2005-04-27 |
| KR20030074097A (ko) | 2003-09-19 |
| US7034005B2 (en) | 2006-04-25 |
| JP2003327536A (ja) | 2003-11-19 |
| US20060025357A1 (en) | 2006-02-02 |
| DK1350510T3 (da) | 2005-08-29 |
| CN1183915C (zh) | 2005-01-12 |
| EP1350510B1 (en) | 2005-05-18 |
| DE60204211T2 (de) | 2006-02-02 |
| HK1056838A1 (en) | 2004-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |