MXPA02010549A - Agente hemostatico, metodo y soporte para aplicacion de un agente de coagulacion sanguinea. - Google Patents

Agente hemostatico, metodo y soporte para aplicacion de un agente de coagulacion sanguinea.

Info

Publication number
MXPA02010549A
MXPA02010549A MXPA02010549A MXPA02010549A MXPA02010549A MX PA02010549 A MXPA02010549 A MX PA02010549A MX PA02010549 A MXPA02010549 A MX PA02010549A MX PA02010549 A MXPA02010549 A MX PA02010549A MX PA02010549 A MXPA02010549 A MX PA02010549A
Authority
MX
Mexico
Prior art keywords
blood
wound
blood clotting
oxyacid
carrier
Prior art date
Application number
MXPA02010549A
Other languages
English (en)
Inventor
James A Patterson
Original Assignee
Biolife Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/592,344 external-priority patent/US6521265B1/en
Priority claimed from US09/766,513 external-priority patent/US20020141964A1/en
Application filed by Biolife Llc filed Critical Biolife Llc
Publication of MXPA02010549A publication Critical patent/MXPA02010549A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/11—Peroxy compounds, peroxides, e.g. hydrogen peroxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

Un agente hemostatico, metodo y portador para interrumpir el flujo sanguineo y otros fluidos del cuerpo que contengan proteinas que fluyan de una herida abierta, y que promueven que sane la herida. Un aspecto amplio esta dirigido a una mezcla substancialmente anhidrida de una sal oxiacida y un donador de proton hidrofilico que hidratara en la presencia de sangre y fluidos corporales y promover la coagulacion sanguinea. Las sales oxiacidas preferidas son las sales alcali y alcalinoterreas de metales de transicion y oxiacidos halogenos con capacidades de oxidacion suficientes como para acelerar la coagulacion sanguinea. Otra modalidad de la invencion incluye el compuesto que contiene una oxisal mas un polimero hidrofilico tal como la carboxi meticelulosa, polivinilo, alcohol, un alginato y todas las gomas solubles. Otra modalidad de la invencion incluye el compuesto formado de una sal oxiacida en combinacion con un donador de proton hidrofilico y un disecador solido que acelera mas los indices de reaccion a la coagulacion sanguinea. El material de intercambio de cation o una mezcla de una sal oxiacida de metal alcali mas sal inorganica acida produce una costra o cubierta protectora sobre la herida para su proteccion y sanado mejorado. El oxigeno producido durante la reaccion substancialmente reduce el nivel de bacterias, virus y hongos en la herida. La resina es de desarrollo mejorado para la mejor toma de fluidos y mas rapida coagulacion.
MXPA02010549A 2000-04-28 2001-04-27 Agente hemostatico, metodo y soporte para aplicacion de un agente de coagulacion sanguinea. MXPA02010549A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20020700P 2000-04-28 2000-04-28
US09/592,344 US6521265B1 (en) 2000-02-09 2000-06-13 Method for applying a blood clotting agent
US09/766,513 US20020141964A1 (en) 2001-01-19 2001-01-19 Composition for arresting the flow of blood and method
PCT/US2001/013765 WO2001082896A1 (en) 2000-04-28 2001-04-27 Hemostatic agent, method and carrier for applying a blood clotting agent

Publications (1)

Publication Number Publication Date
MXPA02010549A true MXPA02010549A (es) 2004-05-17

Family

ID=27394133

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010549A MXPA02010549A (es) 2000-04-28 2001-04-27 Agente hemostatico, metodo y soporte para aplicacion de un agente de coagulacion sanguinea.

Country Status (12)

Country Link
EP (1) EP1276463B1 (es)
JP (2) JP4436994B2 (es)
CN (1) CN100488490C (es)
AT (1) ATE491435T1 (es)
AU (2) AU5739701A (es)
BR (1) BR0110670A (es)
CA (1) CA2345484C (es)
DE (1) DE60143649D1 (es)
IL (2) IL152453A (es)
MX (1) MXPA02010549A (es)
NZ (1) NZ522121A (es)
WO (1) WO2001082896A1 (es)

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BR0110670A (pt) * 2000-04-28 2005-05-24 Biolife Llc Agente hemostático e veìculo de liberação para o mesmo
JP4668510B2 (ja) * 2001-09-29 2011-04-13 持田製薬株式会社 可撓性容器入り局所止血用医薬組成物
WO2003045366A1 (en) * 2001-11-29 2003-06-05 Greystone Medical Group, Inc. Treatment of wounds and compositions employed
DE10204819A1 (de) * 2002-01-31 2003-08-14 Aesculap Ag & Co Kg Blutstillungsmittel und seine Bereitstellung für die Medizin
EP1663090A4 (en) 2003-09-12 2010-07-21 Z Medica Corp HEMOSTATIC AGENT OF CALCIUM ZEOLITE
WO2005027834A2 (en) * 2003-09-12 2005-03-31 Z-Medica Corporation Partially hydrated hemostatic agent
CN101389789B (zh) 2004-01-16 2012-08-08 巴特尔纪念研究所 生产高铁酸盐(vi)的方法和装置
EP1846111B1 (en) 2004-11-12 2011-04-13 Battelle Memorial Institute Decontaminant
GB0500898D0 (en) * 2005-01-18 2005-02-23 Smith & Nephew Gold-protein coagulation
US20060178609A1 (en) 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
WO2006088912A2 (en) 2005-02-15 2006-08-24 Virginia Commonwealth University Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers
US9326995B2 (en) 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
US8304402B2 (en) 2005-05-05 2012-11-06 Binyarco, Llc Composition and method for treating nosebleeds
US20070004995A1 (en) * 2005-06-30 2007-01-04 Horn Jeffrey L Swab device and kit for the delivery of blood clotting materials to a wound site
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US8202532B2 (en) 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
WO2008112657A1 (en) 2007-03-09 2008-09-18 Battelle Memorial Institute Ferrate(vi)-containing compositions and methods of using ferrate(vi)
KR20100017345A (ko) 2007-05-01 2010-02-16 오프론 비.브이. 살생물성 의료장치, 삽입물 및 상처 드레싱
WO2008151041A2 (en) 2007-05-31 2008-12-11 Biolife, Llc Materials and methods for preparation of alkaline earth ferrates from alkaline earth oxides, peroxides, and nitrates
WO2009142823A1 (en) * 2008-03-26 2009-11-26 Battelle Memorial Institute Apparatus and methods of providing diatomic oxygen (o2) using ferrate(vi)-containing compositions
EP2342291A1 (en) 2008-10-17 2011-07-13 Battelle Memorial Institute Corrosion resistant primer coating
EP2381969B1 (en) * 2009-01-27 2016-05-18 REDDRESS Ltd. Methods for the preparation of wound dressings and a bank of wound dressings
EP2393501A1 (en) * 2009-02-05 2011-12-14 Pierre Philippart Method and means for producing tissues and tissues obtained
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
DK2863961T3 (da) 2012-06-22 2019-01-02 Z Medica Llc Hæmostatiske indretninger
US8961479B2 (en) * 2013-03-19 2015-02-24 Biolife, L.L.C. Hemostatic device and method
CN107496449A (zh) * 2016-06-14 2017-12-22 中国科学院生物物理研究所 一种具有止血、杀菌功能的纳米酶止血剂及其应用
IL247786B (en) 2016-09-12 2019-08-29 Plotkin Alexander Covers the wound with a hemostatic action and method and creates it
CN106442986B (zh) * 2016-09-21 2018-05-18 华南农业大学 一种非疾病诊断和治疗目的的检测区域性猪流感病毒亚型分布的方法
US11241386B2 (en) * 2019-02-13 2022-02-08 Biolife, L.L.C. Wound sealing powder
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Also Published As

Publication number Publication date
BR0110670A (pt) 2005-05-24
CA2345484A1 (en) 2001-10-28
EP1276463A1 (en) 2003-01-22
DE60143649D1 (de) 2011-01-27
JP2009235098A (ja) 2009-10-15
EP1276463B1 (en) 2010-12-15
CN1426296A (zh) 2003-06-25
AU5739701A (en) 2001-11-12
AU2001257397B2 (en) 2005-08-04
IL152453A0 (en) 2003-05-29
EP1276463A4 (en) 2006-05-17
JP2003531850A (ja) 2003-10-28
JP4436994B2 (ja) 2010-03-24
NZ522121A (en) 2005-11-25
IL189630A0 (en) 2008-06-05
CN100488490C (zh) 2009-05-20
IL152453A (en) 2008-03-20
CA2345484C (en) 2008-01-29
ATE491435T1 (de) 2011-01-15
WO2001082896A1 (en) 2001-11-08

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