BR0110670A - Agente hemostático e veìculo de liberação para o mesmo - Google Patents

Agente hemostático e veìculo de liberação para o mesmo

Info

Publication number
BR0110670A
BR0110670A BR0110670-8A BR0110670A BR0110670A BR 0110670 A BR0110670 A BR 0110670A BR 0110670 A BR0110670 A BR 0110670A BR 0110670 A BR0110670 A BR 0110670A
Authority
BR
Brazil
Prior art keywords
blood
wound
oxyacid
invention includes
another embodiment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BR0110670-8A
Other languages
English (en)
Inventor
James A Patterson
John A Thompson
Talmadge Kelly Keene
James W Reding
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biolife LLC
Original Assignee
Biolife LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/592,344 external-priority patent/US6521265B1/en
Priority claimed from US09/766,513 external-priority patent/US20020141964A1/en
Application filed by Biolife LLC filed Critical Biolife LLC
Publication of BR0110670A publication Critical patent/BR0110670A/pt
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/11—Peroxy compounds, peroxides, e.g. hydrogen peroxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"AGENTE HEMOSTáTICO E VEìCULO DE LIBERAçãO PARA O MESMO". Uma composição e um método para interromper o fluxo de sangue e outros fluidos corporais contendo proteínas fluindo de uma ferida aberta e para promover a cicatrização da ferida. No método, um composto substancialmente anidro de um ferrato salino é provido para um uso único que se hidratará na presença de sangue e de fluidos corporais para produzir Fe^ +++^ promovendo assim a coagulação quando aplicada à ferida por um tempo suficiente para interromper substancial sangue adicional e outros fluxos de fluidos corporais da ferida. O composto é formado de um sal selecionado do grupo consistindo de H, Li, Na, K, Rb, Cs e Fr. Entretanto, para reduzir ou eliminar a sensação de ardor, o composto poderá ser formado tendo um sal selecionado do grupo consistindo de Be, Mg, Ca, Sr, Ba, Ra, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, Ge, Zr, Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, In, Sn, Hf, Ta, W, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Al, As, NH~ 4~, e N(C~ 4~H~ 9~)~ 6~. A composição, preferida também inclui um material de troca catiónica tal como uma resina troca-íons sulfonada em uma mistura que se hidratará na presença de sangue e outros fluidos corporais para produzir Fe^ +++^ promovendo assim a coagulação do sangue e do fluido corporal e para produzir oxigênio. O material de troca catiónica produz um película ou revestimento protetor sobre a ferida para proteção e cicatrização melhorada. Oxigênio produzido durante a reação reduz substancialmente o nível de bactérias, virus e fungos na ferida.
BR0110670-8A 2000-04-28 2001-04-27 Agente hemostático e veìculo de liberação para o mesmo Pending BR0110670A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20020700P 2000-04-28 2000-04-28
US09/592,344 US6521265B1 (en) 2000-02-09 2000-06-13 Method for applying a blood clotting agent
US09/766,513 US20020141964A1 (en) 2001-01-19 2001-01-19 Composition for arresting the flow of blood and method
PCT/US2001/013765 WO2001082896A1 (en) 2000-04-28 2001-04-27 Hemostatic agent, method and carrier for applying a blood clotting agent

Publications (1)

Publication Number Publication Date
BR0110670A true BR0110670A (pt) 2005-05-24

Family

ID=27394133

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110670-8A Pending BR0110670A (pt) 2000-04-28 2001-04-27 Agente hemostático e veìculo de liberação para o mesmo

Country Status (12)

Country Link
EP (1) EP1276463B1 (pt)
JP (2) JP4436994B2 (pt)
CN (1) CN100488490C (pt)
AT (1) ATE491435T1 (pt)
AU (2) AU5739701A (pt)
BR (1) BR0110670A (pt)
CA (1) CA2345484C (pt)
DE (1) DE60143649D1 (pt)
IL (2) IL152453A (pt)
MX (1) MXPA02010549A (pt)
NZ (1) NZ522121A (pt)
WO (1) WO2001082896A1 (pt)

Families Citing this family (33)

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JP4436994B2 (ja) * 2000-04-28 2010-03-24 バイオライフ，リミティド ライアビリティー カンパニー 止血剤、血液凝固剤の塗布方法、血液凝固剤の基剤
JP4668510B2 (ja) * 2001-09-29 2011-04-13 持田製薬株式会社 可撓性容器入り局所止血用医薬組成物
US20030133991A1 (en) * 2001-11-29 2003-07-17 Greystone Medical Group, Inc. Treatment of wounds and compositions employed
DE10204819A1 (de) * 2002-01-31 2003-08-14 Aesculap Ag & Co Kg Blutstillungsmittel und seine Bereitstellung für die Medizin
EP1663090A4 (en) 2003-09-12 2010-07-21 Z Medica Corp HEMOSTATIC AGENT OF CALCIUM ZEOLITE
DE602004030264D1 (de) 2003-09-12 2011-01-05 Z Medica Corp Teilweise hydriertes hämostatisches mittel
US8449756B2 (en) 2004-01-16 2013-05-28 Battelle Memorial Institute Method for producing ferrate (V) and/or (VI)
EP1846111B1 (en) 2004-11-12 2011-04-13 Battelle Memorial Institute Decontaminant
GB0500898D0 (en) * 2005-01-18 2005-02-23 Smith & Nephew Gold-protein coagulation
US20060178609A1 (en) 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
CA2597940A1 (en) 2005-02-15 2006-08-24 Virginia Commonwealth University Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers
US9326995B2 (en) 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
US8304402B2 (en) 2005-05-05 2012-11-06 Binyarco, Llc Composition and method for treating nosebleeds
US20070004995A1 (en) * 2005-06-30 2007-01-04 Horn Jeffrey L Swab device and kit for the delivery of blood clotting materials to a wound site
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US8202532B2 (en) 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US8663607B2 (en) 2007-03-09 2014-03-04 Battelle Memorial Institute Ferrate(VI)-containing compositions and methods of using ferrate(VI)
BRPI0809869A2 (pt) 2007-05-01 2014-09-30 Oplon Bv Dispositivos médicos, implantes e curativos para feridas biocidas
WO2008151041A2 (en) 2007-05-31 2008-12-11 Biolife, Llc Materials and methods for preparation of alkaline earth ferrates from alkaline earth oxides, peroxides, and nitrates
WO2009142823A1 (en) * 2008-03-26 2009-11-26 Battelle Memorial Institute Apparatus and methods of providing diatomic oxygen (o2) using ferrate(vi)-containing compositions
EP2342291A1 (en) 2008-10-17 2011-07-13 Battelle Memorial Institute Corrosion resistant primer coating
PL2381969T3 (pl) * 2009-01-27 2016-12-30 Sposoby wytwarzania opatrunków na rany oraz bank opatrunków
NZ594698A (en) * 2009-02-05 2013-08-30 Pierre Philippart Method and means for producing tissues and tissues obtained
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
CA3183404A1 (en) 2012-06-22 2013-12-27 Teleflex Life Sciences Limited Hemostatic devices
US8961479B2 (en) * 2013-03-19 2015-02-24 Biolife, L.L.C. Hemostatic device and method
CN107496449A (zh) * 2016-06-14 2017-12-22 中国科学院生物物理研究所 一种具有止血、杀菌功能的纳米酶止血剂及其应用
IL247786B (en) 2016-09-12 2019-08-29 Plotkin Alexander Covers the wound with a hemostatic action and method and creates it
CN106442986B (zh) * 2016-09-21 2018-05-18 华南农业大学 一种非疾病诊断和治疗目的的检测区域性猪流感病毒亚型分布的方法
US11241386B2 (en) * 2019-02-13 2022-02-08 Biolife, L.L.C. Wound sealing powder
KR102438006B1 (ko) * 2020-02-25 2022-08-30 주식회사 테라시온 바이오메디칼 다용도 지혈제 조성물 및 그 제조방법

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Also Published As

Publication number Publication date
WO2001082896A1 (en) 2001-11-08
DE60143649D1 (de) 2011-01-27
EP1276463B1 (en) 2010-12-15
CA2345484C (en) 2008-01-29
EP1276463A4 (en) 2006-05-17
CA2345484A1 (en) 2001-10-28
IL152453A (en) 2008-03-20
AU5739701A (en) 2001-11-12
MXPA02010549A (es) 2004-05-17
ATE491435T1 (de) 2011-01-15
CN1426296A (zh) 2003-06-25
IL189630A0 (en) 2008-06-05
JP2003531850A (ja) 2003-10-28
JP2009235098A (ja) 2009-10-15
JP4436994B2 (ja) 2010-03-24
AU2001257397B2 (en) 2005-08-04
NZ522121A (en) 2005-11-25
EP1276463A1 (en) 2003-01-22
CN100488490C (zh) 2009-05-20
IL152453A0 (en) 2003-05-29

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]

Free format text: DE ACORDO COM ART. 34 " II " DA LPI ( LEI 9279, DE 14/05/96 ) , O EXAME FICA SUSPENSO PARA QUE O REQUERENTE APRESENTE DOCUMENTOS NECESSARIOS A REGULARIZACAO DO PROCESSO E EXAME DO PEDIDO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM OS ARTIGOS 8O, 11, 13, 24 E 25 DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.