MXPA02005221A - Arreglo de oligomeros con oligomeros de adn y/o adn sobre una superficie. - Google Patents

Arreglo de oligomeros con oligomeros de adn y/o adn sobre una superficie.

Info

Publication number
MXPA02005221A
MXPA02005221A MXPA02005221A MXPA02005221A MXPA02005221A MX PA02005221 A MXPA02005221 A MX PA02005221A MX PA02005221 A MXPA02005221 A MX PA02005221A MX PA02005221 A MXPA02005221 A MX PA02005221A MX PA02005221 A MXPA02005221 A MX PA02005221A
Authority
MX
Mexico
Prior art keywords
oligomers
general formula
pna
dna oligomers
oligomer array
Prior art date
Application number
MXPA02005221A
Other languages
English (en)
Inventor
Berlin Kurt
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Publication of MXPA02005221A publication Critical patent/MXPA02005221A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Dental Preparations (AREA)

Abstract

La invencion se relaciona con un arreglo de oligomeros con oligomeros de APN (acidos nucleicos peptidicos) y/o de ADN sobre una superficie, el cual comprende oligomeros de respectivamente entre 6 y 20 monomeros nucleobases, siendo que estas en cada caso comprenden un minimo de una secuencia de formula general DDCGDD o de formula general DDTGDD o de formula general HHCGHH o de formula general HHCAHH, siendo que H significa una de las bases adenina (A), citosina (C) o timina (T), y (D) constituye una de las bases adenina (A), guanina (G) o timina (T), y siendo que el sitio de los oligomeros sobre la superficie se correlaciona con la secuencia de los oligomeros. Los arreglos oligomericos de conformidad con la invencion se usan para detectar metilaciones de citosina en el ADN genomico.
MXPA02005221A 1999-11-25 2000-11-24 Arreglo de oligomeros con oligomeros de adn y/o adn sobre una superficie. MXPA02005221A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19957827A DE19957827C2 (de) 1999-11-25 1999-11-25 Verwendung eines Oligomer-Arrays mit PNA- und/oder DNA-Oligomeren auf einer Oberfläche
PCT/DE2000/004301 WO2001038565A2 (de) 1999-11-25 2000-11-24 Oligomer-array mit pna- und/oder dna-oligomeren auf einer oberfläche

Publications (1)

Publication Number Publication Date
MXPA02005221A true MXPA02005221A (es) 2004-08-23

Family

ID=7930999

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02005221A MXPA02005221A (es) 1999-11-25 2000-11-24 Arreglo de oligomeros con oligomeros de adn y/o adn sobre una superficie.

Country Status (16)

Country Link
US (1) US6936419B1 (es)
EP (2) EP1816216A3 (es)
JP (2) JP2003514570A (es)
CN (1) CN1413263B (es)
AT (1) ATE362548T1 (es)
AU (1) AU784238B2 (es)
CA (1) CA2390312C (es)
DE (2) DE19957827C2 (es)
DK (1) DK1232287T3 (es)
ES (1) ES2287049T3 (es)
IL (1) IL149801A0 (es)
IS (1) IS2445B (es)
MX (1) MXPA02005221A (es)
NZ (1) NZ518548A (es)
PT (1) PT1232287E (es)
WO (1) WO2001038565A2 (es)

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Also Published As

Publication number Publication date
ES2287049T3 (es) 2007-12-16
JP2007175051A (ja) 2007-07-12
WO2001038565A3 (de) 2001-11-15
NZ518548A (en) 2004-12-24
IS6364A (is) 2002-04-26
IS2445B (is) 2008-11-15
PT1232287E (pt) 2007-08-21
CA2390312C (en) 2011-05-31
DE19957827A1 (de) 2001-06-21
EP1232287B1 (de) 2007-05-16
CN1413263A (zh) 2003-04-23
CN1413263B (zh) 2012-07-04
CA2390312A1 (en) 2001-05-31
WO2001038565A2 (de) 2001-05-31
DK1232287T3 (da) 2007-09-24
AU784238B2 (en) 2006-02-23
US6936419B1 (en) 2005-08-30
EP1232287A2 (de) 2002-08-21
IL149801A0 (en) 2002-11-10
JP2003514570A (ja) 2003-04-22
ATE362548T1 (de) 2007-06-15
DE50014333D1 (de) 2007-06-28
EP1816216A3 (de) 2009-06-03
AU2827001A (en) 2001-06-04
DE19957827C2 (de) 2003-06-12
EP1816216A2 (de) 2007-08-08

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