MXPA02004619A - Metodo para tratar enfermedades virales y otros trastornos, alterando la expresion del gen inmediato mediante la administracion del peptido t. - Google Patents

Metodo para tratar enfermedades virales y otros trastornos, alterando la expresion del gen inmediato mediante la administracion del peptido t.

Info

Publication number
MXPA02004619A
MXPA02004619A MXPA02004619A MXPA02004619A MXPA02004619A MX PA02004619 A MXPA02004619 A MX PA02004619A MX PA02004619 A MXPA02004619 A MX PA02004619A MX PA02004619 A MXPA02004619 A MX PA02004619A MX PA02004619 A MXPA02004619 A MX PA02004619A
Authority
MX
Mexico
Prior art keywords
thr
residu
carboxy
est
ser
Prior art date
Application number
MXPA02004619A
Other languages
English (en)
Inventor
Farrand Dean
Original Assignee
Advanced Immuni T Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Immuni T Inc filed Critical Advanced Immuni T Inc
Publication of MXPA02004619A publication Critical patent/MXPA02004619A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describe un metodo para inhibir la replicacion viral y para tratar las condiciones neurotroficas, al regular/inhibir la expresion del gen inmediato temprano en celulas hospederas que comprende administrarle una cantidad inhibitoria/reguladora efectiva de un Peptido de la Formula (I). Ra-Ser-Thr-Thr-Thr-Asn-Tyr-Rb en donde Ra representa un residuo terminal amino Ala- o D- Ala y Rb representan un residuo terminal carboxilo -Thr o - Thr-amida o un derivado de estos con un residuo adicional Cys- en una o ambas de las terminales amino y carboxilo, o un Peptido de la Formula (II): R1-R2-R3-R4-R5 en donde R1 es un residuo terminal amino Thr-, Ser-, Asn-, Glu-, Arg-, Ile- o Leu-, R2 es Thr, Ser, o Asp, R3 es Thr, Ser, Asn, Arg, Gln, Lys, o Trp, R4 es Tyr y R5 es preferiblemente un residuo terminal carboxilo -Thr, -Arg o Gly un derivado de estos con un D-aminoacido correspondiente como el residuo terminal amino, y/o un derivado amida correspondiente en el residuo terminal carboxilo y/o adicionalmente un residuo Cys- en una o ambas de las terminales amino y carboxilo, en un portador fisiologicamente adecuado.
MXPA02004619A 1999-11-09 2000-11-09 Metodo para tratar enfermedades virales y otros trastornos, alterando la expresion del gen inmediato mediante la administracion del peptido t. MXPA02004619A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16436399P 1999-11-09 1999-11-09
PCT/US2000/042030 WO2001034095A2 (en) 1999-11-09 2000-11-09 A method for treating viral diseases and other disorders by altering immediate gene expression through administration of peptide t

Publications (1)

Publication Number Publication Date
MXPA02004619A true MXPA02004619A (es) 2004-09-10

Family

ID=22594146

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02004619A MXPA02004619A (es) 1999-11-09 2000-11-09 Metodo para tratar enfermedades virales y otros trastornos, alterando la expresion del gen inmediato mediante la administracion del peptido t.

Country Status (10)

Country Link
EP (1) EP1242109A4 (es)
JP (1) JP2003528817A (es)
KR (1) KR20020063182A (es)
CN (1) CN1635913A (es)
AU (1) AU3080001A (es)
CA (1) CA2389392A1 (es)
IL (1) IL149443A0 (es)
MX (1) MXPA02004619A (es)
WO (1) WO2001034095A2 (es)
ZA (1) ZA200203120B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242564B1 (en) * 1986-06-03 2001-06-05 Candace B. Pert Treatment of tropical spastic paresis with peptide T
ES2222625T3 (es) * 1992-03-27 2005-02-01 Advanced Immuni T, Inc. Peptido t y peptidos asociados destinados al tratamiento de la inflamacion incluyendo la esclerosis multiple.

Also Published As

Publication number Publication date
EP1242109A2 (en) 2002-09-25
CN1635913A (zh) 2005-07-06
IL149443A0 (en) 2002-11-10
WO2001034095A2 (en) 2001-05-17
CA2389392A1 (en) 2001-05-17
KR20020063182A (ko) 2002-08-01
AU3080001A (en) 2001-06-06
EP1242109A4 (en) 2004-06-02
WO2001034095A8 (en) 2001-11-29
JP2003528817A (ja) 2003-09-30
ZA200203120B (en) 2002-11-27

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