MX9804574A - Preparacion de (11beta, 16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h- pregna-1,4-dieno,[17, 16-d]oxazol-3, 20-diona. - Google Patents

Preparacion de (11beta, 16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h- pregna-1,4-dieno,[17, 16-d]oxazol-3, 20-diona.

Info

Publication number
MX9804574A
MX9804574A MX9804574A MX9804574A MX9804574A MX 9804574 A MX9804574 A MX 9804574A MX 9804574 A MX9804574 A MX 9804574A MX 9804574 A MX9804574 A MX 9804574A MX 9804574 A MX9804574 A MX 9804574A
Authority
MX
Mexico
Prior art keywords
beta
dieno
pregna
oxazole
dione
Prior art date
Application number
MX9804574A
Other languages
English (en)
Inventor
Luigi Forte
Calogero Cancellieri
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of MX9804574A publication Critical patent/MX9804574A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un proceso para preparar el compuesto de la (11 beta-16 beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2 '-metil-5'-H-pregna,1,4-dieno[17,16-d]oxazol-3,20- diona, el cual comprende hacer reaccionar el compuesto de la (11 beta, 16 beta)-11,21-dihidroxi-2'-metil-5'H-pregna-1,4-dieno [17,16-d]oxazol-3,20-diona con anhídrido succínico en un alquiléster de C1-C4 de un ácido carboxílico de C1-C4 como solvente, en presencia de un catalizador básico.
MX9804574A 1995-12-13 1998-06-08 Preparacion de (11beta, 16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h- pregna-1,4-dieno,[17, 16-d]oxazol-3, 20-diona. MX9804574A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95119627 1995-12-13

Publications (1)

Publication Number Publication Date
MX9804574A true MX9804574A (es) 1998-09-30

Family

ID=8219883

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9804574A MX9804574A (es) 1995-12-13 1998-06-08 Preparacion de (11beta, 16beta)-21-(3-carboxi-3-oxopropoxi)-11-hidroxi-2'-metil-5'h- pregna-1,4-dieno,[17, 16-d]oxazol-3, 20-diona.

Country Status (21)

Country Link
US (1) US6417350B1 (es)
EP (1) EP0879242B1 (es)
JP (1) JP4076097B2 (es)
KR (1) KR100433566B1 (es)
CN (1) CN100351266C (es)
AT (1) ATE192454T1 (es)
AU (1) AU707406B2 (es)
CA (1) CA2238692C (es)
DE (1) DE69608134T2 (es)
EA (1) EA000731B1 (es)
ES (1) ES2145507T3 (es)
GR (1) GR3033940T3 (es)
HK (1) HK1017690A1 (es)
HU (1) HU226668B1 (es)
MX (1) MX9804574A (es)
NO (1) NO309094B1 (es)
NZ (1) NZ324299A (es)
PT (1) PT879242E (es)
SI (1) SI0879242T1 (es)
WO (1) WO1997021723A1 (es)
ZA (1) ZA9610413B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2157476T3 (es) * 1995-12-13 2001-08-16 Lepetit Spa Preparacion de (11beta,16beta)-21-(acetiloxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dien(17,16-d)oxazol-3,20-diona.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1141930B (it) * 1980-04-28 1986-10-08 Lepetit Spa Esteri idrosolubili di steroido-ossazoli e loro composizioni farmaceutiche
GB8730216D0 (en) * 1987-12-29 1988-02-03 Lepetit Spa Process for preparation of pregnenooxazolines
CN1092066A (zh) * 1993-03-04 1994-09-14 商业部科学研究院 6-甲基-1，2，3-噁噻嗪-4(3h)-酮-2，2-二氧化物及其盐的合成方法
ES2157476T3 (es) * 1995-12-13 2001-08-16 Lepetit Spa Preparacion de (11beta,16beta)-21-(acetiloxi)-11-hidroxi-2'-metil-5'h-pregna-1,4-dien(17,16-d)oxazol-3,20-diona.

Also Published As

Publication number Publication date
SI0879242T1 (en) 2000-08-31
ZA9610413B (en) 1997-09-09
DE69608134D1 (de) 2000-06-08
KR19990072025A (ko) 1999-09-27
CA2238692C (en) 2004-07-20
NO982413D0 (no) 1998-05-27
WO1997021723A1 (en) 1997-06-19
CN100351266C (zh) 2007-11-28
JP4076097B2 (ja) 2008-04-16
US6417350B1 (en) 2002-07-09
ATE192454T1 (de) 2000-05-15
AU707406B2 (en) 1999-07-08
EA199800551A1 (ru) 1998-12-24
EP0879242B1 (en) 2000-05-03
ES2145507T3 (es) 2000-07-01
CN1204340A (zh) 1999-01-06
HU226668B1 (en) 2009-06-29
KR100433566B1 (ko) 2004-07-16
NO982413L (no) 1998-05-27
AU1175797A (en) 1997-07-03
NZ324299A (en) 1999-04-29
PT879242E (pt) 2000-10-31
GR3033940T3 (en) 2000-11-30
NO309094B1 (no) 2000-12-11
DE69608134T2 (de) 2001-01-11
HK1017690A1 (en) 1999-11-26
CA2238692A1 (en) 1997-06-19
EP0879242A1 (en) 1998-11-25
HUP9903535A3 (en) 2000-04-28
HUP9903535A2 (hu) 2000-03-28
JP2000503633A (ja) 2000-03-28
EA000731B1 (ru) 2000-02-28

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