MX9710409A - A human edg-2 receptor homolog. - Google Patents

A human edg-2 receptor homolog.

Info

Publication number
MX9710409A
MX9710409A MX9710409A MX9710409A MX9710409A MX 9710409 A MX9710409 A MX 9710409A MX 9710409 A MX9710409 A MX 9710409A MX 9710409 A MX9710409 A MX 9710409A MX 9710409 A MX9710409 A MX 9710409A
Authority
MX
Mexico
Prior art keywords
hedg
molecules
encode
receptor homolog
nucleic acid
Prior art date
Application number
MX9710409A
Other languages
Spanish (es)
Other versions
MXPA97010409A (en
Inventor
Roger Coleman
Karl J Guegler
Janice Au-Young
Olga Bandman
Jeffrey J Seilhamer
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MX9710409A publication Critical patent/MX9710409A/en
Publication of MXPA97010409A publication Critical patent/MXPA97010409A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention provides nucleic acid and amino acid sequences that identify and encode a novel EDG-2 receptor homolog (hedg) expressed in human rheumatoid synovium. The present invention also provides for probes for the detection of nucleotide sequences encoding of HEDG or HEDG-like molecules, antisense molecules to the nucleotide sequences which encode HEDG, diagnostic tests based on HEDG encoding nucleic acid molecules, genetically engineered expression vectors and host cells for the production of purified HEDG, antibodies capable of binding specifically to HEDG, and antagonists and inhibitors with specific binding activity for the polypeptide HEDG.
MXPA/A/1997/010409A 1995-06-20 1997-12-18 Homologo de receptor de edg-2 hum MXPA97010409A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US000352 1993-01-04
US35295P 1995-06-20 1995-06-20
US56781795A 1995-12-06 1995-12-06
US567817 1995-12-06
PCT/US1996/010618 WO1997000952A2 (en) 1995-06-20 1996-06-20 A human edg-2 receptor homolog

Publications (2)

Publication Number Publication Date
MX9710409A true MX9710409A (en) 1998-07-31
MXPA97010409A MXPA97010409A (en) 1998-11-09

Family

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Also Published As

Publication number Publication date
AU718269B2 (en) 2000-04-13
AU6388696A (en) 1997-01-22
WO1997000952A2 (en) 1997-01-09
JPH11508135A (en) 1999-07-21
EP0840787A2 (en) 1998-05-13
WO1997000952A3 (en) 1997-03-20
CA2224799A1 (en) 1997-01-09

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