MX9709338A - A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR. - Google Patents
A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR.Info
- Publication number
- MX9709338A MX9709338A MX9709338A MX9709338A MX9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A
- Authority
- MX
- Mexico
- Prior art keywords
- calr
- encode
- transmembrane receptor
- provides
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Laminated Bodies (AREA)
- Diaphragms And Bellows (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The present invention provides nucleotide and amino acid sequences that identify and encode a novel C5a-like seven transmembrane receptor (CALR) expressed in human mast cells. The present invention also provides for antisense molecules to the nucleotide sequences which encode CALR, expression vectors for the production of purified CALR, antibodies capable of binding specifically to CALR, hybridization probes or oligonucleotides for the detection of CALR-encoding nucleotide sequences, diagnostic tests based on CALR-encoding nucleic acid molecules, genetically engineered host cells for the expression of CALR, and antagonists and inhibitors of the polypeptide CALR.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46235595A | 1995-06-05 | 1995-06-05 | |
US462355 | 1995-06-05 | ||
PCT/US1996/008596 WO1996039511A2 (en) | 1995-06-05 | 1996-06-03 | A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR |
Publications (2)
Publication Number | Publication Date |
---|---|
MXPA97009338A MXPA97009338A (en) | 1998-02-01 |
MX9709338A true MX9709338A (en) | 1998-02-28 |
Family
ID=23836136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9709338A MX9709338A (en) | 1995-06-05 | 1996-06-03 | A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0832231A2 (en) |
JP (1) | JPH11507513A (en) |
AU (1) | AU718311B2 (en) |
CA (1) | CA2223038A1 (en) |
MX (1) | MX9709338A (en) |
WO (1) | WO1996039511A2 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1921695A (en) * | 1995-02-17 | 1996-09-04 | Human Genome Sciences, Inc. | Human g-protein coupled receptor |
EP0948536B1 (en) * | 1996-01-30 | 2007-06-13 | The Scripps Research Institute | A g protein-coupled receptor with an enlarged extracellular domain |
JPH1087700A (en) * | 1996-06-17 | 1998-04-07 | Smithkline Beecham Corp | Treatment and screening using c3a receptor and c3a |
US6063596A (en) * | 1997-12-11 | 2000-05-16 | Incyte Pharmaceuticals, Inc. | G-protein coupled receptors associated with immune response |
WO2000008155A2 (en) * | 1998-08-07 | 2000-02-17 | Incyte Pharmaceuticals, Inc. | Human receptor-associated proteins |
AU2001271656A1 (en) * | 2000-06-29 | 2002-01-14 | Deltagen, Inc. | Transgenic mice containing targeted gene disruptions |
EP2371861B1 (en) | 2002-01-25 | 2017-08-09 | Novo Nordisk A/S | Monoclonal antibodies against extracellular loops of C5aR |
RU2009110154A (en) | 2006-08-22 | 2010-09-27 | Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД (AU) | ANTIBODIES AGAINST C5aR WITH IMPROVED PROPERTIES |
US8268972B2 (en) | 2008-02-20 | 2012-09-18 | G2 Inflammation Pty Ltd | Humanized anti-C5aR antibodies |
DK2718322T3 (en) | 2011-06-06 | 2018-12-03 | Novo Nordisk As | THERAPEUTIC ANTIBODIES |
WO2017211371A2 (en) * | 2016-06-10 | 2017-12-14 | Herlev Hospital | Calr and jak2 vaccine compositions |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508384A (en) * | 1992-09-10 | 1996-04-16 | New York University | Polypeptide derived from a popamine receptor, and compositions and methods thereof |
JPH07503145A (en) * | 1992-11-17 | 1995-04-06 | イコス コーポレイション | Novel 7-transmembrane receptor |
-
1996
- 1996-06-03 JP JP9501136A patent/JPH11507513A/en not_active Ceased
- 1996-06-03 AU AU63273/96A patent/AU718311B2/en not_active Ceased
- 1996-06-03 EP EP96922382A patent/EP0832231A2/en not_active Ceased
- 1996-06-03 MX MX9709338A patent/MX9709338A/en not_active Application Discontinuation
- 1996-06-03 WO PCT/US1996/008596 patent/WO1996039511A2/en not_active Application Discontinuation
- 1996-06-03 CA CA002223038A patent/CA2223038A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JPH11507513A (en) | 1999-07-06 |
AU718311B2 (en) | 2000-04-13 |
AU6327396A (en) | 1996-12-24 |
WO1996039511A2 (en) | 1996-12-12 |
EP0832231A2 (en) | 1998-04-01 |
WO1996039511A3 (en) | 1997-01-09 |
CA2223038A1 (en) | 1996-12-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |