MX9709338A - A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR. - Google Patents

A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR.

Info

Publication number
MX9709338A
MX9709338A MX9709338A MX9709338A MX9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A MX 9709338 A MX9709338 A MX 9709338A
Authority
MX
Mexico
Prior art keywords
calr
encode
transmembrane receptor
provides
present
Prior art date
Application number
MX9709338A
Other languages
Spanish (es)
Other versions
MXPA97009338A (en
Inventor
Roger Coleman
Janice Au-Young
Olga Bandman
Jeffrey J Seilhamer
Original Assignee
Incyte Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc filed Critical Incyte Pharma Inc
Publication of MXPA97009338A publication Critical patent/MXPA97009338A/en
Publication of MX9709338A publication Critical patent/MX9709338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Laminated Bodies (AREA)
  • Diaphragms And Bellows (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides nucleotide and amino acid sequences that identify and encode a novel C5a-like seven transmembrane receptor (CALR) expressed in human mast cells. The present invention also provides for antisense molecules to the nucleotide sequences which encode CALR, expression vectors for the production of purified CALR, antibodies capable of binding specifically to CALR, hybridization probes or oligonucleotides for the detection of CALR-encoding nucleotide sequences, diagnostic tests based on CALR-encoding nucleic acid molecules, genetically engineered host cells for the expression of CALR, and antagonists and inhibitors of the polypeptide CALR.
MX9709338A 1995-06-05 1996-06-03 A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR. MX9709338A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46235595A 1995-06-05 1995-06-05
US462355 1995-06-05
PCT/US1996/008596 WO1996039511A2 (en) 1995-06-05 1996-06-03 A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR

Publications (2)

Publication Number Publication Date
MXPA97009338A MXPA97009338A (en) 1998-02-01
MX9709338A true MX9709338A (en) 1998-02-28

Family

ID=23836136

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9709338A MX9709338A (en) 1995-06-05 1996-06-03 A C5a-LIKE SEVEN TRANSMEMBRANE RECEPTOR.

Country Status (6)

Country Link
EP (1) EP0832231A2 (en)
JP (1) JPH11507513A (en)
AU (1) AU718311B2 (en)
CA (1) CA2223038A1 (en)
MX (1) MX9709338A (en)
WO (1) WO1996039511A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1921695A (en) * 1995-02-17 1996-09-04 Human Genome Sciences, Inc. Human g-protein coupled receptor
EP0948536B1 (en) * 1996-01-30 2007-06-13 The Scripps Research Institute A g protein-coupled receptor with an enlarged extracellular domain
JPH1087700A (en) * 1996-06-17 1998-04-07 Smithkline Beecham Corp Treatment and screening using c3a receptor and c3a
US6063596A (en) * 1997-12-11 2000-05-16 Incyte Pharmaceuticals, Inc. G-protein coupled receptors associated with immune response
WO2000008155A2 (en) * 1998-08-07 2000-02-17 Incyte Pharmaceuticals, Inc. Human receptor-associated proteins
AU2001271656A1 (en) * 2000-06-29 2002-01-14 Deltagen, Inc. Transgenic mice containing targeted gene disruptions
EP2371861B1 (en) 2002-01-25 2017-08-09 Novo Nordisk A/S Monoclonal antibodies against extracellular loops of C5aR
RU2009110154A (en) 2006-08-22 2010-09-27 Джи2 ИНФЛЕММЕЙШН ПТИ ЛТД (AU) ANTIBODIES AGAINST C5aR WITH IMPROVED PROPERTIES
US8268972B2 (en) 2008-02-20 2012-09-18 G2 Inflammation Pty Ltd Humanized anti-C5aR antibodies
DK2718322T3 (en) 2011-06-06 2018-12-03 Novo Nordisk As THERAPEUTIC ANTIBODIES
WO2017211371A2 (en) * 2016-06-10 2017-12-14 Herlev Hospital Calr and jak2 vaccine compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5508384A (en) * 1992-09-10 1996-04-16 New York University Polypeptide derived from a popamine receptor, and compositions and methods thereof
JPH07503145A (en) * 1992-11-17 1995-04-06 イコス　コーポレイション Novel 7-transmembrane receptor

Also Published As

Publication number Publication date
JPH11507513A (en) 1999-07-06
AU718311B2 (en) 2000-04-13
AU6327396A (en) 1996-12-24
WO1996039511A2 (en) 1996-12-12
EP0832231A2 (en) 1998-04-01
WO1996039511A3 (en) 1997-01-09
CA2223038A1 (en) 1996-12-12

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Legal Events

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FA Abandonment or withdrawal