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Application filed by Sanofi Winthrop IncfiledCriticalSanofi Winthrop Inc
Publication of MX9706876ApublicationCriticalpatent/MX9706876A/es
Publication of MXPA97006876ApublicationCriticalpatent/MXPA97006876A/es
C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
C07D487/04—Ortho-condensed systems
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A—HUMAN NECESSITIES
A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
A61P9/00—Drugs for disorders of the cardiovascular system
A61P9/12—Antihypertensives
Abstract
Derivados de pirazolo[3,4-d]pirimidin-4-ona 6-sustituida, composiciones farmacéuticas que los contienen y métodos para a) efectuar la inhibicion c-GMP-fosfodiesterasa, b) tratar la falla del corazon y/o hipertension, c) invertir o reducir la tolerancia inducida por nitrato y d) tratar la angina de pecho, enfermedad del corazon congestionado e infarto al miocardio utilizando los mismos.
MXPA/A/1997/006876A1995-03-101997-09-09Pirazolo[3,4-d]pirimidin-4-onas 6-sustituidas y composiciones y metodo para su uso
MXPA97006876A
(es)
Process for preparation pharmaceutical composition combination of hypertensin converting enzyme inhibitor with a diuretic for treating microcirculation disorders
7-£1h-pyrol-3-yl|-substitute 3,5-dihydpoxyhept-6-enoic acids, 7-£1h-pyrrol-3-yl|-substituted 3,5-dihydroxyheptanoic acids, their corresponding ù-lactones and salts, processes for their preparation, their use as medicaments, pharmaceutical products and intermediates