MX9704679A - Composicion antibacteriana liposomal de baja rigidez. - Google Patents
Composicion antibacteriana liposomal de baja rigidez.Info
- Publication number
- MX9704679A MX9704679A MX9704679A MX9704679A MX9704679A MX 9704679 A MX9704679 A MX 9704679A MX 9704679 A MX9704679 A MX 9704679A MX 9704679 A MX9704679 A MX 9704679A MX 9704679 A MX9704679 A MX 9704679A
- Authority
- MX
- Mexico
- Prior art keywords
- low rigidity
- therapeutic agent
- lipid
- antibacterial composition
- liposomal formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Abstract
La invencion se refiere a una formulacion liposomal que contiene por lo menos un agente terapéutico tal como un antibiotico y a un método para el tratamiento de infecciones bacterianas a través de la administracion de dicha formulacion. Se provee una formulacion liposomal, multilaminar, de baja rigidez, libre de colesterol, que comprende un lípido neutro, un lípido anionico y por lo menos un agente terapéutico, en donde la formulacion liposomal mejora la penetracion del agente terapéutico dentro de la célula bacteriana. Una composicion preferida de lípido es dipalmitoilfosfatidilcolina (DPPC): dimiristoilfosfatidilglicerol (DMPG) a una relacion de 10:1 a 15:1, con una concentracion total de lípido que varía de 5 a 85 mM.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/363,416 US5662929A (en) | 1994-12-23 | 1994-12-23 | Therapeutic liposomal formulation |
| US08363416 | 1994-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9704679A true MX9704679A (es) | 1998-07-31 |
| MXPA97004679A MXPA97004679A (es) | 1998-11-09 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996019972A1 (en) | 1996-07-04 |
| NZ297364A (en) | 2000-01-28 |
| ES2196092T3 (es) | 2003-12-16 |
| CA2206296A1 (en) | 1996-07-04 |
| BR9510423A (pt) | 2003-01-07 |
| ATE235229T1 (de) | 2003-04-15 |
| JP4523078B2 (ja) | 2010-08-11 |
| KR100438657B1 (ko) | 2004-08-18 |
| US5662929A (en) | 1997-09-02 |
| BRPI9510423B8 (pt) | 2019-11-05 |
| AU4251096A (en) | 1996-07-19 |
| EP0806941B1 (en) | 2003-03-26 |
| EP0806941A1 (en) | 1997-11-19 |
| AU702463B2 (en) | 1999-02-25 |
| DE69530124T2 (de) | 2004-02-05 |
| DK0806941T3 (da) | 2003-07-21 |
| KR980700062A (ko) | 1998-03-30 |
| CA2206296C (en) | 2007-05-22 |
| PT806941E (pt) | 2003-08-29 |
| DE69530124D1 (de) | 2003-04-30 |
| JPH10511363A (ja) | 1998-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration | ||
| MM | Annulment or lapse due to non-payment of fees |