DE69530124D1 - Liposomale antibakterielle zusammensetzung mit geringer festigkeit - Google Patents

Liposomale antibakterielle zusammensetzung mit geringer festigkeit

Info

Publication number
DE69530124D1
DE69530124D1 DE69530124T DE69530124T DE69530124D1 DE 69530124 D1 DE69530124 D1 DE 69530124D1 DE 69530124 T DE69530124 T DE 69530124T DE 69530124 T DE69530124 T DE 69530124T DE 69530124 D1 DE69530124 D1 DE 69530124D1
Authority
DE
Germany
Prior art keywords
low strength
antibacterial composition
liposomal
agent
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69530124T
Other languages
English (en)
Other versions
DE69530124T2 (de
Inventor
Jacqueline Lagace
Christian Beaulac
Sebastien Clement-Major
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Montreal
Original Assignee
Universite de Montreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23430112&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69530124(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universite de Montreal filed Critical Universite de Montreal
Application granted granted Critical
Publication of DE69530124D1 publication Critical patent/DE69530124D1/de
Publication of DE69530124T2 publication Critical patent/DE69530124T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
DE69530124T 1994-12-23 1995-12-22 Liposomale antibakterielle zusammensetzung mit geringer festigkeit Expired - Lifetime DE69530124T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/363,416 US5662929A (en) 1994-12-23 1994-12-23 Therapeutic liposomal formulation
PCT/CA1995/000713 WO1996019972A1 (en) 1994-12-23 1995-12-22 Low rigidity liposomal antibacterial composition
US363416 1999-07-29

Publications (2)

Publication Number Publication Date
DE69530124D1 true DE69530124D1 (de) 2003-04-30
DE69530124T2 DE69530124T2 (de) 2004-02-05

Family

ID=23430112

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530124T Expired - Lifetime DE69530124T2 (de) 1994-12-23 1995-12-22 Liposomale antibakterielle zusammensetzung mit geringer festigkeit

Country Status (14)

Country Link
US (1) US5662929A (de)
EP (1) EP0806941B1 (de)
JP (1) JP4523078B2 (de)
KR (1) KR100438657B1 (de)
AT (1) ATE235229T1 (de)
AU (1) AU702463B2 (de)
BR (2) BRPI9510423B8 (de)
CA (1) CA2206296C (de)
DE (1) DE69530124T2 (de)
DK (1) DK0806941T3 (de)
ES (1) ES2196092T3 (de)
NZ (1) NZ297364A (de)
PT (1) PT806941E (de)
WO (1) WO1996019972A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511477B2 (en) * 1997-03-13 2003-01-28 Biocardia, Inc. Method of drug delivery to interstitial regions of the myocardium
US6443949B2 (en) * 1997-03-13 2002-09-03 Biocardia, Inc. Method of drug delivery to interstitial regions of the myocardium
US6054133A (en) * 1997-07-10 2000-04-25 The Regents Of The University Of California Anti-microbial targeting for intracellular pathogens
US6613352B2 (en) * 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
US6365138B1 (en) * 2000-04-07 2002-04-02 The Regents Of The University Of California Compositions for metabolic protection and repair of lips
EP1289570B1 (de) * 2000-06-16 2008-09-10 Sloan-Kettering Institute For Cancer Research Liposomale einkapselung von alphastrahlern, und deren verwendung
DK1353647T3 (da) * 2000-12-27 2011-06-14 Gilead Sciences Inc Inhalerbar aztreonam til behandling og forebyggelse af bakterielle lungeinfektioner
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
DE10214983A1 (de) * 2002-04-04 2004-04-08 TransMIT Gesellschaft für Technologietransfer mbH Vernebelbare Liposomen und ihre Verwendung zur pulmonalen Applikation von Wirkstoffen
US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
CN1747738B (zh) * 2002-10-29 2010-11-24 川塞夫有限公司 缓释抗感染剂
US7718189B2 (en) * 2002-10-29 2010-05-18 Transave, Inc. Sustained release of antiinfectives
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
RU2341267C2 (ru) * 2003-10-15 2008-12-20 Пари Фарма Гмбх Жидкий препарат, содержащий тобрамицин
US20050214224A1 (en) * 2003-11-04 2005-09-29 Nektar Therapeutics Lipid formulations for spontaneous drug encapsulation
US8226975B2 (en) 2005-12-08 2012-07-24 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
DE102009031274A1 (de) 2009-06-30 2011-01-13 Justus-Liebig-Universität Giessen Liposomen zur pulmonalen Applikation
CN103874481B (zh) * 2011-07-13 2016-09-28 铸造有限责任公司 用于向鼻咽粘膜靶递送治疗剂的方法及装置
EP4005576B1 (de) 2012-05-21 2023-12-13 Insmed Incorporated Systeme zur behandlung von lungenentzündungen
AU2013352259B2 (en) 2012-11-29 2018-06-14 Insmed Incorporated Stabilized vancomycin formulations
US9895385B2 (en) 2014-05-15 2018-02-20 Insmed Incorporated Methods for treating pulmonary non-tuberculous mycobacterial infections
EP3177269A4 (de) 2014-08-04 2018-02-28 Zoneone Pharma, Inc. Fernladung von schwach wasserlöslichen medikamenten in lipidvesikel
ES2574615B1 (es) * 2014-12-19 2017-07-24 Biopraxis Research Aie Nanopartícula lipídica de tobramicina
RU2020112725A (ru) * 2017-10-02 2021-11-08 Аридис Фармасьютикалс, Инк. Композиции и способы для борьбы с инфекциями, вызванными синегнойной палочкой (pseudomonas aeruginosa)
JP7460534B2 (ja) 2018-03-30 2024-04-02 インスメッド インコーポレイテッド リポソーム医薬品の連続製造方法
CN117017999A (zh) * 2023-09-20 2023-11-10 四川大学 一种夫西地酸磷脂复合物及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4981692A (en) * 1983-03-24 1991-01-01 The Liposome Company, Inc. Therapeutic treatment by intramammary infusion
US4753788A (en) * 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US4952405A (en) * 1988-10-20 1990-08-28 Liposome Technology, Inc. Method of treating M. avium infection
US5006343A (en) * 1988-12-29 1991-04-09 Benson Bradley J Pulmonary administration of pharmaceutically active substances
PT100486B (pt) * 1992-05-14 1999-07-30 Ineti Inst Nac Engenh E Tecnol Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
AU3244393A (en) * 1992-12-02 1994-06-22 Vestar, Inc. Antibiotic formulation and process

Also Published As

Publication number Publication date
AU4251096A (en) 1996-07-19
EP0806941A1 (de) 1997-11-19
EP0806941B1 (de) 2003-03-26
ES2196092T3 (es) 2003-12-16
KR980700062A (ko) 1998-03-30
DE69530124T2 (de) 2004-02-05
ATE235229T1 (de) 2003-04-15
AU702463B2 (en) 1999-02-25
MX9704679A (es) 1998-07-31
BRPI9510423B8 (pt) 2019-11-05
JPH10511363A (ja) 1998-11-04
BR9510423A (pt) 2003-01-07
WO1996019972A1 (en) 1996-07-04
NZ297364A (en) 2000-01-28
US5662929A (en) 1997-09-02
JP4523078B2 (ja) 2010-08-11
CA2206296A1 (en) 1996-07-04
PT806941E (pt) 2003-08-29
CA2206296C (en) 2007-05-22
DK0806941T3 (da) 2003-07-21
KR100438657B1 (ko) 2004-08-18

Similar Documents

Publication Publication Date Title
DE69530124D1 (de) Liposomale antibakterielle zusammensetzung mit geringer festigkeit
MXPA02002895A (es) Tratamiento topico de infecciones por estreptococcus.
EP0195643A3 (en) Compositions and method of controlling transdermal penetration of topical and systemic agents
WO2001030802A3 (en) Therapeutic treatments comprising administration of certain steroids for blood cell deficiencies
BRPI9915480B8 (pt) azalídeos de 13 membros, composições farmacêuticas compreendendo os mesmos, método para sua preparação bem como seus usos.
HUP9602498A2 (hu) Antimikrobiális hatású gyógyászati készítmények
PT78628A (en) Pharmaceutical composition with reduced toxicity
KR950026524A (ko) 피부질환 치료용 의약조성물
NZ510153A (en) Tan-1057 derivatives with reduced toxicity and their use in medicaments for treating bacterial infections in humans and mammals
DK1135020T3 (da) Bipest-behandlinger
IE881410L (en) Anticoccidial composition
DE68916956D1 (de) Aktives mittel: lipid-komplex mit hohem verhältnis.
ES8607728A1 (es) Procedimiento de preparacion de una nueva composicion anti- biotica sinergetica, de uso veterinario
GR3004655T3 (de)
Beardmore RECALCITRANT SPOROTRICHOSIS: A REPORT OF A PATIENT TREATED WITH VARIOUS THERAPIES INCLUDING ORAL MICONAZOLE AND 5‐FLUOKOCYTOSINE
DE69941459D1 (de) Verfahren zur herstellung von essbaren zusammenstellungen mit antibakteriellen wirkstoffen
Olay et al. Experimental Staphylococcus aureus osteomyelitis treated with fosfomycin and cephazolin: Single and combined therapy.
ES2086518T3 (es) Compuesto farmaceutico con accion cicatrizante.
WO1992018090A3 (en) Antimicrobial oral compositions
Dellamonica et al. Evaluation of rifampicin combined with a synergic antibiotic in severe staphylococcal infection. Report of selection of resistant mutants in seven cases.
AU1575688A (en) Medicinal composition for treating and preventing diseases caused by cytotoxicity by cellular mediation, incorporating at least one pyridine derivate as active principle
Zhang The clinical study of cefamandole nafate.
Dellamonica et al. Selection of mutant rifampicin-resistant Staphylococcus aureus in patients given rifampicin associated with another antibiotic. Three case-reports.
UA30359A (uk) Спосіб лікування гнійних ран
PL332035A1 (en) Transdermal therapeutic system including an estriol-containing composition of active substances

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R119 Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee

Ref document number: 806941

Country of ref document: EP

Effective date: 20110701

R073 Re-establishment requested

Ref document number: 806941

Country of ref document: EP

R074 Re-establishment allowed

Ref document number: 806941

Country of ref document: EP

R082 Change of representative

Ref document number: 806941

Country of ref document: EP

Representative=s name: CHRISTOPHERSEN & PARTNER, PATENTANWAELTE, 40479 DU

R074 Re-establishment allowed

Ref document number: 806941

Country of ref document: EP

Effective date: 20120215