MX9704560A - Receptor novedoso. - Google Patents
Receptor novedoso.Info
- Publication number
- MX9704560A MX9704560A MX9704560A MX9704560A MX9704560A MX 9704560 A MX9704560 A MX 9704560A MX 9704560 A MX9704560 A MX 9704560A MX 9704560 A MX9704560 A MX 9704560A MX 9704560 A MX9704560 A MX 9704560A
- Authority
- MX
- Mexico
- Prior art keywords
- rat forebrain
- forebrain tissue
- binds
- compound
- novel receptor
- Prior art date
Links
- 210000004129 prosencephalon Anatomy 0.000 abstract 6
- 229940126062 Compound A Drugs 0.000 abstract 2
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Un receptor en forma substancialmente pura que se obtiene a partir de tejido de prosencéfalo de rata caracterizado porque, a) el compuesto A se une a él con una Kd de 48mM para tejido de prosencéfalo de rata; b) el compuesto A se une a él con una Bmax de 220 pmol/g de proteína para tejido de prosencéfalo de rata; c) el compuesto D se une a él con una Kd de 2nM para tejido de prosencéfalo de rata; d) el compuesto B se une a él con una Bmax de 220 pmol/g de proteína para tejido de prosencéfalo de rata; y receptores homologos de otras fuentes que comparten por lo menos 85% de homología con el tejido de prosencéfalo de rata.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9425502.3 | 1994-12-17 | ||
| GBGB9425502.3A GB9425502D0 (en) | 1994-12-17 | 1994-12-17 | Novel receptor |
| PCT/EP1995/004998 WO1996018650A1 (en) | 1994-12-17 | 1995-12-11 | Novel receptor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9704560A true MX9704560A (es) | 1997-10-31 |
| MXPA97004560A MXPA97004560A (es) | 1998-07-03 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| GB9425502D0 (en) | 1995-02-15 |
| EP0807122A1 (en) | 1997-11-19 |
| JPH10511083A (ja) | 1998-10-27 |
| CA2207921A1 (en) | 1996-06-20 |
| FI972558A (fi) | 1997-06-16 |
| NO972771D0 (no) | 1997-06-16 |
| PL320747A1 (en) | 1997-10-27 |
| AU4345896A (en) | 1996-07-03 |
| CN1175262A (zh) | 1998-03-04 |
| AU710150B2 (en) | 1999-09-16 |
| CZ187697A3 (en) | 1997-10-15 |
| BR9510060A (pt) | 1998-06-02 |
| HUT77077A (hu) | 1998-03-02 |
| NO972771L (no) | 1997-08-15 |
| NZ298059A (en) | 2000-03-27 |
| US5985334A (en) | 1999-11-16 |
| FI972558A0 (fi) | 1997-06-16 |
| WO1996018650A1 (en) | 1996-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA200100829B (en) | Peptide antagonists of zonulin and methods for use of the same | |
| AUPO755097A0 (en) | Receptor agonist and antagonist | |
| BG103189A (en) | Substituted 6,5-heterobicyclic derivatives | |
| IL226637A0 (en) | An isolated heterodimeric cytokine receptor | |
| RS20130234A1 (en) | Therapeutic human anti-il-1r1 monoclonal antibody | |
| JO2034B1 (en) | Isotopes of the hormone peptide its uses and the chemical compounds it contains | |
| HK1103763A1 (en) | Human orphan g protein-coupled receptor rup3 | |
| AU1652197A (en) | Novel estrogen receptor | |
| DE69734157D1 (en) | Parathyroidhormon-verwandthe peptidanaloge | |
| CY2610B2 (en) | Prevention and treatment of skeletal disorder with EP2 receptor subtype selective prostaglandin E2 a gonists | |
| IL181578A0 (en) | Antibodies which are specifically immunoreactive with hedgehog interacting proteins and a hybridoma producing such antibodies | |
| MX9804588A (es) | Uso de composiciones que comprenden blanqueador de halogeno para suavidad mejorada a la piel. | |
| MX9604374A (es) | Polietilenos hidrofilicos modificados en polvo de peso molecular elevado y/o ultraelevado. | |
| BG104916A (en) | Calcilytic compounds | |
| CO5460266A1 (es) | Novedosos analogos de la somatostatina | |
| YU2500A (sh) | Alatrofloksacin parenteralni preparati | |
| NZ504471A (en) | An Ox receptor distinct from known alpha 2-adenoreceptors and imidazoline receptors (I1 and I2) with an affinity for compounds of the oxazoline class | |
| AU2001245209A1 (en) | Screening methods for bone morphogenetic mimetics | |
| MX9704560A (es) | Receptor novedoso. | |
| HK1064683A1 (en) | Receptor of the edb fibronectin domains (II) | |
| NZ337601A (en) | Gamma-1 and gamma-3 anti-human CD23 monoclonal antibodies and use thereof as therapeutics by inhibiting IgE expression | |
| MXPA04002058A (es) | Prueba. | |
| MX9603199A (es) | Antagonistas de receptores a endotelina. | |
| JO1999B1 (en) | Isotopes of the hormone 'LH-RH' have their uses and the chemical compounds they contain | |
| AU1967199A (en) | Kv2.1 antagonists |