MX9604634A - Composiciones para suministro controlado, liquidas - Google Patents

Composiciones para suministro controlado, liquidas

Info

Publication number
MX9604634A
MX9604634A MX9604634A MX9604634A MX9604634A MX 9604634 A MX9604634 A MX 9604634A MX 9604634 A MX9604634 A MX 9604634A MX 9604634 A MX9604634 A MX 9604634A MX 9604634 A MX9604634 A MX 9604634A
Authority
MX
Mexico
Prior art keywords
controlled release
compositions
liquid
liquid delivery
delivery compositions
Prior art date
Application number
MX9604634A
Other languages
English (en)
Other versions
MXPA96004634A (es
Inventor
Gerald L Yewey
Nancy L Krinick
Richard L Dunn
Michael L Radomsky
Gerbrand Brouwer
Arthur J Tipton
Original Assignee
Atrix Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22843701&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9604634(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Atrix Lab Inc filed Critical Atrix Lab Inc
Publication of MX9604634A publication Critical patent/MX9604634A/es
Publication of MXPA96004634A publication Critical patent/MXPA96004634A/es

Links

Classifications

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    • A61K9/20—Pills, tablets, discs, rods
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
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    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
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    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)

Abstract

La presente invencion se refiere a un sistema polimérico adecuado para uso como un implante de liberacion controlada para la liberacion controlada de un agente activo, el sistema está caracterizado porque comprende: a) una matriz microporosa solida de polímero biocompatible, biodegradable, termoplástico, el polímero es insoluble en un medio acuoso; y b) un agente activo incorporado en un componente de liberacion controlada, particulado, biodegradable, el componente de liberacion controlada particulado es sustancialmente insoluble en el medio acuoso, y el componente de liberacion controlada está embebido dentro de la matriz microporosa; en donde la matriz microporosa se prepara por contacto entre el medio acuoso y una composicion de suministro la cual incluye un solvente orgánico biocompatible el cual tiene un intervalo de solubilidad de miscible a dispersable en un medio acuoso, el polímero termoplástico biocompatible, y el agente activo se incorporan en el componente de liberacion controlada particulado, biodegradable.
MXPA/A/1996/004634A 1994-04-08 1996-10-07 Composiciones para suministro controlado, liquidas MXPA96004634A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22514094A 1994-04-08 1994-04-08
US225,140 1994-04-08
US225140 1994-04-08

Publications (2)

Publication Number Publication Date
MX9604634A true MX9604634A (es) 1997-11-29
MXPA96004634A MXPA96004634A (es) 1998-07-03

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Publication number Publication date
DE69534780D1 (de) 2006-04-20
EP1125577A2 (en) 2001-08-22
CA2187353C (en) 2007-05-22
ATE317690T1 (de) 2006-03-15
DK1125577T3 (da) 2006-06-19
JP2009029821A (ja) 2009-02-12
CA2582666A1 (en) 1995-10-19
CA2582666C (en) 2010-05-25
EP0754032B1 (en) 2001-12-05
US5744153A (en) 1998-04-28
DE69534780T2 (de) 2006-10-05
KR100374098B1 (ko) 2003-06-09
DE69524398D1 (de) 2002-01-17
ES2171186T3 (es) 2002-09-01
AU684931B2 (en) 1998-01-08
DK0754032T3 (da) 2002-04-02
BR9507313A (pt) 1997-10-07
WO1995027481A1 (en) 1995-10-19
EP1125577A3 (en) 2003-01-08
DE69524398T2 (de) 2002-07-18
CA2187353A1 (en) 1995-10-19
EP1125577B1 (en) 2006-02-15
BR9507313B8 (pt) 2016-06-07
ATE209907T1 (de) 2001-12-15
PT754032E (pt) 2002-05-31
NZ283282A (en) 1998-01-26
KR970702029A (ko) 1997-05-13
ES2258495T3 (es) 2006-09-01
JP4259610B2 (ja) 2009-04-30
EP0754032A1 (en) 1997-01-22
AU2129495A (en) 1995-10-30
JPH09511741A (ja) 1997-11-25
JP4974987B2 (ja) 2012-07-11
US5780044A (en) 1998-07-14
US5759563A (en) 1998-06-02

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