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Application filed by Kirin BreweryfiledCriticalKirin Brewery
Priority claimed from PCT/JP1995/000208external-prioritypatent/WO1995021919A2/en
Publication of MX9504057ApublicationCriticalpatent/MX9504057A/en
The present invention relates to thrombopoietin (TPO) polypeptides having the biological activity of specifically stimulating or increasing platelet production comprising the amino acid sequence 1-332 of SEQ ID NO: 6 or a derivative thereof, DNA molecules encoding TPO polypeptides, processes for production of the polypeptides, antibodies specifically immunoreactive with the polypeptides, pharmaceutical compositions comprising the polypeptides, and methods for using the polypeptides in treatment of platelet disorders such as thrombocytopenia.
MX9504057A1994-02-141995-02-14Protein having tpo activity.
MX9504057A
(en)
Chimeric polypeptide having the antigenic determinants of four proteins of l. infantum, polynucleotides encoding same, methods of production and use thereof in therapeutic compositions