MX9401465A - Matriz para espectroscopia de masas por desorcion laser asistida por matrices. - Google Patents
Matriz para espectroscopia de masas por desorcion laser asistida por matrices.Info
- Publication number
- MX9401465A MX9401465A MX9401465A MX9401465A MX9401465A MX 9401465 A MX9401465 A MX 9401465A MX 9401465 A MX9401465 A MX 9401465A MX 9401465 A MX9401465 A MX 9401465A MX 9401465 A MX9401465 A MX 9401465A
- Authority
- MX
- Mexico
- Prior art keywords
- matrices
- mass spectroscopy
- laser desorption
- matrix
- assisted
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
- H01J49/0463—Desorption by laser or particle beam, followed by ionisation as a separate step
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6872—Methods for sequencing involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/2826—Collecting by adsorption or absorption
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Optics & Photonics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
La presente invención se relaciona a una composición que contiene una fenona que está sustituida en el núcleo fenilo, una sal de amonio y un compuesto de alto peso molecular, y el uso de dicha composición para la composición para la espectroscopía de masas por desorción laser asistida por matrices, de secuencias de oligonucleótidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH59193 | 1993-02-26 | ||
CH223393 | 1993-07-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9401465A true MX9401465A (es) | 1994-08-31 |
Family
ID=25685050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9401465A MX9401465A (es) | 1993-02-26 | 1994-02-25 | Matriz para espectroscopia de masas por desorcion laser asistida por matrices. |
Country Status (4)
Country | Link |
---|---|
US (1) | US5506348A (es) |
EP (1) | EP0612994A3 (es) |
JP (1) | JPH06322274A (es) |
MX (1) | MX9401465A (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436635B1 (en) * | 1992-11-06 | 2002-08-20 | Boston University | Solid phase sequencing of double-stranded nucleic acids |
US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
WO1994021822A1 (en) * | 1993-03-19 | 1994-09-29 | Sequenom, Inc. | Dna sequencing by mass spectrometry via exonuclease degradation |
US6428955B1 (en) | 1995-03-17 | 2002-08-06 | Sequenom, Inc. | DNA diagnostics based on mass spectrometry |
US7803529B1 (en) * | 1995-04-11 | 2010-09-28 | Sequenom, Inc. | Solid phase sequencing of biopolymers |
US20060063193A1 (en) * | 1995-04-11 | 2006-03-23 | Dong-Jing Fu | Solid phase sequencing of double-stranded nucleic acids |
US5830655A (en) | 1995-05-22 | 1998-11-03 | Sri International | Oligonucleotide sizing using cleavable primers |
DE19617011C2 (de) * | 1996-04-27 | 2000-11-02 | Bruker Daltonik Gmbh | Matrixkomponentengemisch für die matrixunterstützte Laserdesorption und Ionisierung sowie Verfahren zur Zubereitung eines Matrixkomponentengemisches |
EP1460083B1 (en) | 1996-11-06 | 2006-01-18 | Sequenom, Inc. | Analysing method and apparatus |
US6133436A (en) * | 1996-11-06 | 2000-10-17 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
AU735416B2 (en) * | 1996-11-06 | 2001-07-05 | Sequenom, Inc. | Dna diagnostics based on mass spectrometry |
US7285422B1 (en) | 1997-01-23 | 2007-10-23 | Sequenom, Inc. | Systems and methods for preparing and analyzing low volume analyte array elements |
US6140053A (en) | 1996-11-06 | 2000-10-31 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
US6268131B1 (en) | 1997-12-15 | 2001-07-31 | Sequenom, Inc. | Mass spectrometric methods for sequencing nucleic acids |
US6723564B2 (en) | 1998-05-07 | 2004-04-20 | Sequenom, Inc. | IR MALDI mass spectrometry of nucleic acids using liquid matrices |
DE19834070B4 (de) | 1998-07-29 | 2007-02-15 | Bruker Daltonik Gmbh | Ionisierung hochmolekularer Substanzen durch Laserdesorption aus flüssigen Matrices |
WO2002004936A1 (en) * | 2000-07-11 | 2002-01-17 | Japan Science And Technology Corporation | Probe for mass spectrometry of liquid sample |
EP1332000B1 (en) * | 2000-10-30 | 2012-06-20 | Sequenom, Inc. | Method for delivery of submicroliter volumes onto a substrate |
US20090180931A1 (en) | 2007-09-17 | 2009-07-16 | Sequenom, Inc. | Integrated robotic sample transfer device |
US7888127B2 (en) | 2008-01-15 | 2011-02-15 | Sequenom, Inc. | Methods for reducing adduct formation for mass spectrometry analysis |
JP5569264B2 (ja) * | 2010-08-31 | 2014-08-13 | 株式会社島津製作所 | マトリクス支援レーザー脱離イオン化飛行時間型質量分析装置を用いたイオン源内解裂によるrna配列決定法 |
JP5727407B2 (ja) * | 2012-03-13 | 2015-06-03 | 株式会社島津製作所 | 質量分析用マトリックスの添加剤 |
EP2950092B1 (en) | 2013-03-08 | 2016-11-23 | Shimadzu Corporation | Mass spectrometry method using matrix |
US9305756B2 (en) | 2013-03-13 | 2016-04-05 | Agena Bioscience, Inc. | Preparation enhancements and methods of use for MALDI mass spectrometry |
US9885725B2 (en) | 2014-03-27 | 2018-02-06 | Shimadzu Corporation | MALDI analysis of hydrophobic compounds using 2(3),5-dihydoxybenzoate with a long alkyl chain as an additive to MALDI matrix |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4227919A (en) * | 1979-08-06 | 1980-10-14 | Stauffer Chemical Company | 1-Hydroxy-2-(alkylketo)-4,4,6,6-tetramethyl cyclohexen-3,5-dione herbicides |
DE4017804C2 (de) * | 1989-08-22 | 1994-11-24 | Finnigan Mat Gmbh | Verfahren und Verwendung einer Vorrichtung zur matrix-unterstützten Laserdesorption von Analytmolekülen, insbesondere Biomolekülen |
US5118937A (en) * | 1989-08-22 | 1992-06-02 | Finnigan Mat Gmbh | Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules |
GB2236184B (en) * | 1989-09-12 | 1993-07-28 | Finnigan Mat Ltd | Method of preparing samples for laser spectrometry analysis |
US5045694A (en) * | 1989-09-27 | 1991-09-03 | The Rockefeller University | Instrument and method for the laser desorption of ions in mass spectrometry |
-
1994
- 1994-02-17 EP EP94810091A patent/EP0612994A3/de not_active Ceased
- 1994-02-23 JP JP6025239A patent/JPH06322274A/ja active Pending
- 1994-02-24 US US08/201,308 patent/US5506348A/en not_active Expired - Fee Related
- 1994-02-25 MX MX9401465A patent/MX9401465A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP0612994A2 (de) | 1994-08-31 |
EP0612994A3 (de) | 1996-03-06 |
JPH06322274A (ja) | 1994-11-22 |
US5506348A (en) | 1996-04-09 |
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