MX9303245A - Compuestos novedosos de fosfonato que contienen nitrogeno cuaternario, composiciones farmaceuticas y metodo para tratar el metabolismo anormal del calcio y del fosfonato. - Google Patents
Compuestos novedosos de fosfonato que contienen nitrogeno cuaternario, composiciones farmaceuticas y metodo para tratar el metabolismo anormal del calcio y del fosfonato.Info
- Publication number
- MX9303245A MX9303245A MX9303245A MX9303245A MX9303245A MX 9303245 A MX9303245 A MX 9303245A MX 9303245 A MX9303245 A MX 9303245A MX 9303245 A MX9303245 A MX 9303245A MX 9303245 A MX9303245 A MX 9303245A
- Authority
- MX
- Mexico
- Prior art keywords
- present
- phosphonate
- pharmaceutical compositions
- quaternary nitrogen
- calcium
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Chemical group 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 title 2
- 208000021959 Abnormal metabolism Diseases 0.000 title 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 title 1
- 230000006371 metabolic abnormality Effects 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 title 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- -1 nitrogen containing phosphonate compounds Chemical class 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3821—Acyclic saturated acids which can have further substituents on alkyl substituted by B, Si, P or a metal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89135592A | 1992-05-29 | 1992-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX9303245A true MX9303245A (es) | 1994-05-31 |
Family
ID=25398040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX9303245A MX9303245A (es) | 1992-05-29 | 1993-05-31 | Compuestos novedosos de fosfonato que contienen nitrogeno cuaternario, composiciones farmaceuticas y metodo para tratar el metabolismo anormal del calcio y del fosfonato. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0642517A1 (zh) |
| JP (1) | JPH07507305A (zh) |
| KR (1) | KR950701927A (zh) |
| CN (1) | CN1085906A (zh) |
| AU (1) | AU675224B2 (zh) |
| CA (1) | CA2136819A1 (zh) |
| CZ (1) | CZ296694A3 (zh) |
| FI (1) | FI945598A (zh) |
| HU (1) | HUT69732A (zh) |
| IL (1) | IL105831A0 (zh) |
| MX (1) | MX9303245A (zh) |
| NZ (1) | NZ252587A (zh) |
| RU (1) | RU94046139A (zh) |
| SK (1) | SK144594A3 (zh) |
| WO (1) | WO1993024494A1 (zh) |
| ZA (1) | ZA933758B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728650A (en) * | 1993-10-07 | 1998-03-17 | Zeneca Limited | Herbicidal aza bisphosphonic acids and compositions containing the same |
| IL115041A0 (en) * | 1995-08-23 | 1995-12-08 | Yissum Res Dev Co | Novel bisphosphonates process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2534391C2 (de) * | 1975-08-01 | 1983-01-13 | Henkel KGaA, 4000 Düsseldorf | 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren |
| DE4011777A1 (de) * | 1989-04-14 | 1990-10-18 | Ciba Geigy Ag | N-trisubstituierte aminoalkandiphosphonsaeuren |
-
1993
- 1993-05-11 WO PCT/US1993/004469 patent/WO1993024494A1/en not_active Application Discontinuation
- 1993-05-11 RU RU94046139/04A patent/RU94046139A/ru unknown
- 1993-05-11 NZ NZ252587A patent/NZ252587A/en unknown
- 1993-05-11 CA CA002136819A patent/CA2136819A1/en not_active Abandoned
- 1993-05-11 CZ CZ942966A patent/CZ296694A3/cs unknown
- 1993-05-11 KR KR1019940704304A patent/KR950701927A/ko not_active Application Discontinuation
- 1993-05-11 EP EP93911255A patent/EP0642517A1/en not_active Ceased
- 1993-05-11 JP JP6500570A patent/JPH07507305A/ja active Pending
- 1993-05-11 HU HU9403406A patent/HUT69732A/hu unknown
- 1993-05-11 SK SK1445-94A patent/SK144594A3/sk unknown
- 1993-05-11 AU AU42453/93A patent/AU675224B2/en not_active Ceased
- 1993-05-28 IL IL105831A patent/IL105831A0/xx unknown
- 1993-05-28 ZA ZA933758A patent/ZA933758B/xx unknown
- 1993-05-29 CN CN93108225A patent/CN1085906A/zh active Pending
- 1993-05-31 MX MX9303245A patent/MX9303245A/es unknown
-
1994
- 1994-11-28 FI FI945598A patent/FI945598A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ296694A3 (en) | 1995-12-13 |
| FI945598A (fi) | 1995-01-25 |
| FI945598A0 (fi) | 1994-11-28 |
| HU9403406D0 (en) | 1995-02-28 |
| IL105831A0 (en) | 1993-09-22 |
| NZ252587A (en) | 1997-02-24 |
| RU94046139A (ru) | 1996-09-27 |
| AU4245393A (en) | 1993-12-30 |
| JPH07507305A (ja) | 1995-08-10 |
| KR950701927A (ko) | 1995-05-17 |
| HUT69732A (en) | 1995-09-28 |
| EP0642517A1 (en) | 1995-03-15 |
| WO1993024494A1 (en) | 1993-12-09 |
| CA2136819A1 (en) | 1993-12-09 |
| AU675224B2 (en) | 1997-01-30 |
| ZA933758B (en) | 1994-01-20 |
| SK144594A3 (en) | 1995-07-11 |
| CN1085906A (zh) | 1994-04-27 |
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