ZA933758B - Novel quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism. - Google Patents
Novel quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism.Info
- Publication number
- ZA933758B ZA933758B ZA933758A ZA933758A ZA933758B ZA 933758 B ZA933758 B ZA 933758B ZA 933758 A ZA933758 A ZA 933758A ZA 933758 A ZA933758 A ZA 933758A ZA 933758 B ZA933758 B ZA 933758B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- pharmaceutical compositions
- quaternary nitrogen
- treating abnormal
- phosphonate compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3821—Acyclic saturated acids which can have further substituents on alkyl substituted by B, Si, P or a metal
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89135592A | 1992-05-29 | 1992-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA933758B true ZA933758B (en) | 1994-01-20 |
Family
ID=25398040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA933758A ZA933758B (en) | 1992-05-29 | 1993-05-28 | Novel quaternary nitrogen-containing phosphonate compounds, pharmaceutical compositions, and methods of treating abnormal calcium and phosphate metabolism. |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0642517A1 (en) |
| JP (1) | JPH07507305A (en) |
| KR (1) | KR950701927A (en) |
| CN (1) | CN1085906A (en) |
| AU (1) | AU675224B2 (en) |
| CA (1) | CA2136819A1 (en) |
| CZ (1) | CZ296694A3 (en) |
| FI (1) | FI945598A (en) |
| HU (1) | HUT69732A (en) |
| IL (1) | IL105831A0 (en) |
| MX (1) | MX9303245A (en) |
| NZ (1) | NZ252587A (en) |
| RU (1) | RU94046139A (en) |
| SK (1) | SK144594A3 (en) |
| WO (1) | WO1993024494A1 (en) |
| ZA (1) | ZA933758B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728650A (en) * | 1993-10-07 | 1998-03-17 | Zeneca Limited | Herbicidal aza bisphosphonic acids and compositions containing the same |
| IL115041A0 (en) * | 1995-08-23 | 1995-12-08 | Yissum Res Dev Co | Novel bisphosphonates process for their preparation and pharmaceutical compositions containing them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2534391C2 (en) * | 1975-08-01 | 1983-01-13 | Henkel KGaA, 4000 Düsseldorf | 1-Hydroxy-3-aminoalkane-1,1-diphosphonic acids |
| DE4011777A1 (en) * | 1989-04-14 | 1990-10-18 | Ciba Geigy Ag | New tri:alkyl:ammonio 1-hydroxy-alkane-1,1-di:phosphonic acids - are calcium metabolism regulants e.g. for treating osteoporosis of calcium deposition in blood vessels |
-
1993
- 1993-05-11 KR KR1019940704304A patent/KR950701927A/en not_active Application Discontinuation
- 1993-05-11 JP JP6500570A patent/JPH07507305A/en active Pending
- 1993-05-11 CZ CZ942966A patent/CZ296694A3/en unknown
- 1993-05-11 HU HU9403406A patent/HUT69732A/en unknown
- 1993-05-11 SK SK1445-94A patent/SK144594A3/en unknown
- 1993-05-11 AU AU42453/93A patent/AU675224B2/en not_active Ceased
- 1993-05-11 CA CA002136819A patent/CA2136819A1/en not_active Abandoned
- 1993-05-11 RU RU94046139/04A patent/RU94046139A/en unknown
- 1993-05-11 NZ NZ252587A patent/NZ252587A/en unknown
- 1993-05-11 WO PCT/US1993/004469 patent/WO1993024494A1/en not_active Application Discontinuation
- 1993-05-11 EP EP93911255A patent/EP0642517A1/en not_active Ceased
- 1993-05-28 IL IL105831A patent/IL105831A0/en unknown
- 1993-05-28 ZA ZA933758A patent/ZA933758B/en unknown
- 1993-05-29 CN CN93108225A patent/CN1085906A/en active Pending
- 1993-05-31 MX MX9303245A patent/MX9303245A/en unknown
-
1994
- 1994-11-28 FI FI945598A patent/FI945598A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4245393A (en) | 1993-12-30 |
| CN1085906A (en) | 1994-04-27 |
| HUT69732A (en) | 1995-09-28 |
| CZ296694A3 (en) | 1995-12-13 |
| FI945598A (en) | 1995-01-25 |
| HU9403406D0 (en) | 1995-02-28 |
| FI945598A0 (en) | 1994-11-28 |
| IL105831A0 (en) | 1993-09-22 |
| AU675224B2 (en) | 1997-01-30 |
| CA2136819A1 (en) | 1993-12-09 |
| RU94046139A (en) | 1996-09-27 |
| JPH07507305A (en) | 1995-08-10 |
| WO1993024494A1 (en) | 1993-12-09 |
| NZ252587A (en) | 1997-02-24 |
| SK144594A3 (en) | 1995-07-11 |
| EP0642517A1 (en) | 1995-03-15 |
| KR950701927A (en) | 1995-05-17 |
| MX9303245A (en) | 1994-05-31 |
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