MX9300057A - Ester especial del acido 1,4-dihidropiridin-3,5-dicarboxilico y procedimiento para su obtencion. - Google Patents

Ester especial del acido 1,4-dihidropiridin-3,5-dicarboxilico y procedimiento para su obtencion.

Info

Publication number
MX9300057A
MX9300057A MX9300057A MX9300057A MX9300057A MX 9300057 A MX9300057 A MX 9300057A MX 9300057 A MX9300057 A MX 9300057A MX 9300057 A MX9300057 A MX 9300057A MX 9300057 A MX9300057 A MX 9300057A
Authority
MX
Mexico
Prior art keywords
procedure
obtaining
dihidropiridin
dicarboxilico
acid
Prior art date
Application number
MX9300057A
Other languages
English (en)
Inventor
Otto Behner
Hartmund Wollweber
Siegfried Goldmann
Bruno Rosen
Siegfried Zaiss
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9300057A publication Critical patent/MX9300057A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La invención se refiere al nuevo 2,6-dimetil-1-n-propil-4-(4-trifluorometil-fenil)- 1,4 dihidropiridin-3,5-dicarboxilato de dimetilo de fórmula general (I), procedimiento para su obtención y su empleo como medicamento en enfermedades isquémicas, que están unidas a trastornos de la microcirculación. Esta actividad puede presentarse en el sistema de vasos periféricos como el de vasos cerebrales.
MX9300057A 1992-01-14 1993-01-08 Ester especial del acido 1,4-dihidropiridin-3,5-dicarboxilico y procedimiento para su obtencion. MX9300057A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4200714A DE4200714A1 (de) 1992-01-14 1992-01-14 Spezieller 1,4-dihydropyridin-3,5-dicarbonsaeureester, verfahren zu seiner herstellung und seine pharmazeutische verwendung

Publications (1)

Publication Number Publication Date
MX9300057A true MX9300057A (es) 1993-09-01

Family

ID=6449473

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9300057A MX9300057A (es) 1992-01-14 1993-01-08 Ester especial del acido 1,4-dihidropiridin-3,5-dicarboxilico y procedimiento para su obtencion.

Country Status (14)

Country Link
US (1) US5342847A (es)
EP (1) EP0551663A1 (es)
JP (1) JPH0616633A (es)
KR (1) KR930016399A (es)
CN (1) CN1075141A (es)
AU (1) AU3108393A (es)
CA (1) CA2087245A1 (es)
CZ (1) CZ396492A3 (es)
DE (1) DE4200714A1 (es)
HU (1) HUT70155A (es)
IL (1) IL104357A0 (es)
MX (1) MX9300057A (es)
PL (1) PL297393A1 (es)
ZA (1) ZA93210B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4223867A1 (de) * 1992-07-20 1994-01-27 Bayer Ag Spezieller 1,4-Dihydropyridin-3,5-dicarbonsäureester, Verfahren zu seiner Herstellung und seine pharmazeutische Verwendung
CH692199A8 (fr) * 1997-10-09 2002-06-14 Cermol S.A. Composes pyridiques et compositions pharmaceutique
CN102453242B (zh) * 2010-10-27 2013-05-22 中国科学院大连化学物理研究所 一种直接酯化聚合制备聚呋喃二甲酸酯的方法
EP2782573B1 (en) * 2011-11-24 2019-10-09 Richter Gedeon Nyrt. 1,4-dihydropyridine derivatives with hsp modulating activity
CN103044316A (zh) * 2013-01-23 2013-04-17 石家庄学院 一种以咪唑离子液体为催化剂制备1,4-二氢吡啶的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883543A (en) * 1969-05-10 1975-05-13 Bayer Ag N-alkyl-1,4-dihydropyridines
DE2210667A1 (de) * 1972-03-06 1973-09-20 Bayer Ag Kondensiert aromatisch substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US3956341A (en) * 1974-02-21 1976-05-11 Smithkline Corporation 1,3,5-Tricarbo-1,4-dihydropyridines
US4975440A (en) * 1984-09-28 1990-12-04 Byk Gulden Lomberg Chemische Fabrik Gmbh Optically-active 1,4-dihydropyridine
EP0176956B1 (de) * 1984-09-28 1994-06-15 Byk Gulden Lomberg Chemische Fabrik GmbH Neue Diarylverbindungen
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
US4780538A (en) * 1986-02-12 1988-10-25 Merck & Co., Inc. Process for 1,4-dihydropyridine compounds using a titanamine catalyst
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CN1075141A (zh) 1993-08-11
PL297393A1 (en) 1993-10-04
EP0551663A1 (de) 1993-07-21
IL104357A0 (en) 1993-05-13
US5342847A (en) 1994-08-30
AU3108393A (en) 1993-07-15
JPH0616633A (ja) 1994-01-25
CZ396492A3 (en) 1993-12-15
DE4200714A1 (de) 1993-07-15
HU9300075D0 (en) 1993-04-28
CA2087245A1 (en) 1993-07-15
ZA93210B (en) 1993-09-09
KR930016399A (ko) 1993-08-26
HUT70155A (en) 1995-09-28

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